Search Results - "Stone, Andrew P"
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The pathobiology of platelet and megakaryocyte extracellular vesicles: A (c)lot has changed
Published in Journal of thrombosis and haemostasis (01-07-2022)“…Platelet‐derived extracellular vesicles (PEVs) were originally studied for their potential as regulators of coagulation, a function redundant with that of…”
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CD317-Positive Immune Stromal Cells in Human "Mesenchymal Stem Cell" Populations
Published in Frontiers in immunology (06-06-2022)“…Heterogeneity of bone marrow mesenchymal stromal cells (MSCs, frequently referred to as "mesenchymal stem cells") clouds biological understanding and hampers…”
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Extracellular matrices of stromal cell subtypes regulate phenotype and contribute to the stromal microenvironment in vivo
Published in Stem cell research & therapy (18-06-2024)“…Bone marrow stromal cells (BMSCs) are highly heterogeneous, which may reflect their diverse biological functions, including tissue maintenance, haematopoietic…”
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Structural basis of malodour precursor transport in the human axilla
Published in eLife (03-07-2018)“…Mammals produce volatile odours that convey different types of societal information. In , this is now recognised as body odour, a key chemical component of…”
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Corrigendum: CD317-Positive Immune Stromal Cells in Human "Mesenchymal Stem Cell" Populations
Published in Frontiers in immunology (13-12-2022)“…[This corrects the article DOI: 10.3389/fimmu.2022.903796.]…”
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The bone marrow niche from the inside out: how megakaryocytes are shaped by and shape hematopoiesis
Published in Blood (27-01-2022)“…Megakaryocytes (MKs), the largest of the hematopoietic cells, are responsible for producing platelets by extending and depositing long proplatelet extensions…”
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Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies
Published in Cancer discovery (06-02-2023)“…A lack of models that recapitulate the complexity of human bone marrow has hampered mechanistic studies of normal and malignant hematopoiesis and the…”
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Spatial transcriptomics of murine bone marrow megakaryocytes at single-cell resolution
Published in Research and practice in thrombosis and haemostasis (01-05-2023)“…While megakaryocytes are known for making platelets, recent single-cell RNA sequencing data have revealed subpopulations of megakaryocytes with predicted…”
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Bone marrow remodeling supports hematopoiesis in response to immune thrombocytopenia progression in mice
Published in Blood advances (14-12-2021)“…Immune thrombocytopenia (ITP) is an acquired autoimmune condition characterized by both reduced platelet production and the destruction of functionally normal…”
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Thrombocytopenia in a Mouse Model of Pancreatic Cancer
Published in Blood (15-11-2022)Get full text
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Human Bone Marrow Organoids Enable the Study of Hematopoietic Cell-Stromal Interactions and Support the Survival of Malignant Cells from Patients
Published in Blood (15-11-2022)Get full text
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