Search Results - "Stommel, Elijah"
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miRNA extracted from extracellular vesicles is a robust biomarker of amyotrophic lateral sclerosis
Published in Journal of the neurological sciences (15-11-2022)“…We examined miRNA biomarkers for ALS extracted from extracellular vesicles in blood samples using a large and diverse patient and control population. Different…”
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Cyanotoxins and the Nervous System
Published in Toxins (16-09-2021)“…Cyanobacteria are capable of producing a wide range of bioactive compounds with many considered to be toxins. Although there are a number of toxicological…”
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Particulate Air Pollution and Risk of Neuropsychiatric Outcomes. What We Breathe, Swallow, and Put on Our Skin Matters
Published in International journal of environmental research and public health (03-11-2021)“…We appraise newly accumulated evidence of the impact of particle pollution on the brain, the portals of entry, the neural damage mechanisms, and ultimately the…”
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Risk factors for amyotrophic lateral sclerosis: A regional United States case‐control study
Published in Muscle & nerve (01-01-2021)“…Most amyotrophic lateral sclerosis (ALS) cases are considered sporadic, without a known genetic basis, and environmental exposures are thought to play a causal…”
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A perspective on persistent toxicants in veterans and amyotrophic lateral sclerosis: identifying exposures determining higher ALS risk
Published in Journal of neurology (01-05-2022)“…Multiple studies indicate that United States veterans have an increased risk of developing amyotrophic lateral sclerosis (ALS) compared to civilians. However,…”
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Identifying aerosolized cyanobacteria in the human respiratory tract: A proposed mechanism for cyanotoxin-associated diseases
Published in The Science of the total environment (15-12-2018)“…Cyanobacteria produce harmful toxins that have been associated with several acute conditions and chronic human diseases, like gastroenteritis, non-alcoholic…”
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A new method for estimating under-recruitment of a patient registry: a case study with the Ohio Registry of Amyotrophic Lateral Sclerosis
Published in Scientific reports (30-08-2022)“…We developed a disease registry to collect all incident amyotrophic lateral sclerosis (ALS) cases diagnosed during 2016–2018 in Ohio. Due to incomplete case…”
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Keratinous biomarker of mercury exposure associated with amyotrophic lateral sclerosis risk in a nationwide U.S. study
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (02-07-2020)“…Objective: The majority of cases of the fatal neurodegenerative disease amyotrophic lateral sclerosis (ALS) are of unknown etiology. A proportion of these…”
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Alzheimer and Parkinson diseases, frontotemporal lobar degeneration and amyotrophic lateral sclerosis overlapping neuropathology start in the first two decades of life in pollution exposed urbanites and brain ultrafine particulate matter and industrial nanoparticles, including Fe, Ti, Al, V, Ni, Hg, Co, Cu, Zn, Ag, Pt, Ce, La, Pr and W are key players. Metropolitan Mexico City health crisis is in progress
Published in Frontiers in human neuroscience (12-01-2024)“…The neuropathological hallmarks of Alzheimer's disease (AD), Parkinson's disease (PD), frontotemporal lobar degeneration (FTLD), and amyotrophic lateral…”
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Single-domain magnetic particles with motion behavior under electromagnetic AC and DC fields are a fatal cargo in Metropolitan Mexico City pediatric and young adult early Alzheimer, Parkinson, frontotemporal lobar degeneration and amyotrophic lateral sclerosis and in ALS patients
Published in Frontiers in human neuroscience (2024)“…Metropolitan Mexico City (MMC) children and young adults exhibit overlapping Alzheimer and Parkinsons' diseases (AD, PD) and TAR DNA-binding protein 43…”
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Aerosolization of cyanobacteria as a risk factor for amyotrophic lateral sclerosis
Published in Medical hypotheses (01-02-2013)“…Abstract Sporadic amyotrophic lateral sclerosis (sALS) is a fatal neurodegenerative disease with no known cause. There are many clues to suggest an…”
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Fall Risk, Sleep Behavior, and Sleep-Related Movement Disorders in Young Urbanites Exposed to Air Pollution
Published in Journal of Alzheimer's disease (01-01-2023)“…Quadruple aberrant hyperphosphorylated tau, amyloid-β, α-synuclein, and TDP-43 pathology had been documented in 202/203 forensic autopsies in Metropolitan…”
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Toenail mercury Levels are associated with amyotrophic lateral sclerosis risk
Published in Muscle & nerve (01-07-2018)“…ABSTRACT Introduction: Mercury is a neurotoxic metal that is potentially a risk factor for amyotrophic lateral sclerosis (ALS). Consumption of methylmercury…”
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Linking β-methylamino-l-alanine exposure to sporadic amyotrophic lateral sclerosis in Annapolis, MD
Published in Toxicon (Oxford) (01-08-2013)“…Most amyotrophic lateral sclerosis (ALS) cases occur sporadically. Some environmental triggers have been implicated, including beta-methylamino-l-alanine…”
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Sleep matters: Neurodegeneration spectrum heterogeneity, combustion and friction ultrafine particles, industrial nanoparticle pollution, and sleep disorders-Denial is not an option
Published in Frontiers in neurology (27-02-2023)“…Sustained exposures to ubiquitous outdoor/indoor fine particulate matter (PM ), including combustion and friction ultrafine PM (UFPM) and industrial…”
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Gene-Environment-Time Interactions in Neurodegenerative Diseases: Hypotheses and Research Approaches
Published in Annals of Neurosciences (01-12-2018)“…Background: Amyotrophic lateral sclerosis (ALS), Alzheimer’s, and Parkinson’s diseases are age-related neurodegenerative diseases. ALS is not a single entity…”
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Environmental and Occupational Exposures and Amyotrophic Lateral Sclerosis in New England
Published in Neuro-degenerative diseases (01-01-2017)“…Recent data provide support for the concept that potentially modifiable exposures are responsible for sporadic amyotrophic lateral sclerosis (ALS). To evaluate…”
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Amyotrophic Lateral Sclerosis Risk, Family Income, and Fish Consumption Estimates of Mercury and Omega-3 PUFAs in the United States
Published in International journal of environmental research and public health (24-04-2021)“…Most amyotrophic lateral sclerosis (ALS) cases are considered sporadic, without a known genetic basis, and lifestyle factors are suspected to play an etiologic…”
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Is exposure to cyanobacteria an environmental risk factor for amyotrophic lateral sclerosis and other neurodegenerative diseases?
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (01-09-2013)“…Abstract There is a broad scientific consensus that amyotrophic lateral sclerosis (ALS) is caused by gene-environment interactions. Mutations in genes…”
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Detection of cyanotoxins, β-N-methylamino-L-alanine and microcystins, from a lake surrounded by cases of amyotrophic lateral sclerosis
Published in Toxins (29-01-2015)“…A cluster of amyotrophic lateral sclerosis (ALS) has been previously described to border Lake Mascoma in Enfield, NH, with an incidence of ALS approximating 25…”
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