Search Results - "Stolovitzky, G A"

Statistical Analysis of MPSS Measurements: Application to the Study of LPS-Activated Macrophage Gene Expression by Stolovitzky, G. A., Kundaje, A., Held, G. A., Duggar, K. H., Haudenschild, C. D., Zhou, D., Vasicek, T. J., Smith, K. D., Aderem, A., Roach, J. C., Cantor, Charles R.

“…Massively Parallel Signature Sequencing (MPSS), a recently developed high-throughput transcription profiling technology, has the ability to profile almost…”
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Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells by Klein, U, Tu, Y, Stolovitzky, G A, Mattioli, M, Cattoretti, G, Husson, H, Freedman, A, Inghirami, G, Cro, L, Baldini, L, Neri, A, Califano, A, Dalla-Favera, R

“…B cell-derived chronic lymphocytic leukemia (B-CLL) represents a common malignancy whose cell derivation and pathogenesis are unknown. Recent studies have…”
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Transcriptional Analysis of the B Cell Germinal Center Reaction by Klein, Ulf, Tu, Yuhai, Stolovitzky, Gustavo A., Keller, Jeffrey L., Haddad, Joseph, Miljkovic, Vladan, Cattoretti, Giorgio, Califano, Andrea, Dalla-Favera, Riccardo

“…The germinal center (GC) reaction is crucial for T cell-dependent immune responses and is targeted by B cell lymphomagenesis. Here we analyzed the…”
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p53-Mdm2 loop controlled by a balance of its feedback strength and effective dampening using ATM and delayed feedback by Wagner, J, Ma, L, Rice, J J, Hu, W, Levine, A J, Stolovitzky, G A

“…When the genomic integrity of a cell is challenged, its fate is determined in part by signals conveyed by the p53 tumour suppressor protein. It was observed…”
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Motif-based construction of a functional map for mammalian olfactory receptors by Liu, Agatha H., Zhang, Xinmin, Stolovitzky, Gustavo A., Califano, Andrea, Firestein, Stuart J.

“…We applied an automatic and unsupervised system to a nearly complete database of mammalian odor receptor genes. The generated motifs and gene classification…”
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200 mm wafer-scale integration of sub-20 nm sacrificial nanofluidic channels for manipulating and imaging single DNA molecules by Wang, C., Nam, S. W., Cotte, J. M., Peng, H., Jahnes, C. V., Wang, D., Bruce, R., Guillorn, M., Gignac, L. M., Advocate, W. H., Breslin, C. M., Brink, M., Bucchignano, J., Duch, E. A., Galan, A., Kratschmer, E., Litwinowicz, P. J., Lofaro, M. F., Price, W., Rossnagel, S. M., Goldblatt, R. D., Joseph, E. A., Pfeiffer, D., Rao, S. Papa, Royyuru, A., Stolovitzky, G. A., Colgan, E. G., Lin, Q., Polonsky, S.

“…We report sub-20 nm sacrificial nanochannels that enable stretching and translocating single DNA molecules. Sacrificial silicon nano-structures were etched…”
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A Plausible Model for the Digital Response of p53 to DNA Damage by Ma, Lan, Wagner, John, Rice, John Jeremy, Hu, Wenwei, Levine, Arnold J., Stolovitzky, Gustavo A., Austin, Robert H.

“…Recent observations show that the single-cell response of p53 to ionizing radiation (IR) is "digital" in that it is the number of oscillations rather than the…”
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Formation of Regulatory Patterns During Signal Propagation in a Mammalian Cellular Network by Ma'ayan, Avi, Jenkins, Sherry L, Neves, Susana, Hasseldine, Anthony, Grace, Elizabeth, Dubin-Thaler, Benjamin, Eungdamrong, Narat J, Weng, Gehzi, Ram, Prahlad T, Rice, J. Jeremy, Kershenbaum, Aaron, Stolovitzky, Gustavo A, Blitzer, Robert D, Iyengar, Ravi

“…We developed a model of 545 components (nodes) and 1259 interactions representing signaling pathways and cellular machines in the hippocampal CA1 neuron. Using…”
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Tracking CD40 signaling during germinal center development by Basso, Katia, Klein, Ulf, Niu, Huifeng, Stolovitzky, Gustavo A., Tu, Yuhai, Califano, Andrea, Cattoretti, Giorgio, Dalla-Favera, Riccardo

“…Substantial evidence indicates that signaling through the CD40 receptor (CD40) is required for germinal center (GC) and memory B-cell formation. However, it is…”
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Identification of a global gene expression signature of B-chronic lymphocytic leukemia by JELINEK, Diane F, TSCHUMPER, Renee C, STOLOVITZKY, Gustavo A, ITURRIA, Stephen J, TU, Yuhai, LEPRE, Jorge, SHAH, Nigam, KAY, Neil E

“…B-chronic lymphocytic leukemia (B-CLL) is an adult-onset leukemia characterized by significant accumulation of apoptosis-resistant monoclonal B lymphocytes. In…”
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Gene Expression Dynamics during Germinal Center Transit in B Cells by KLEIN, ULF, TU, YUHAI, STOLOVITZKY, GUSTAVO A., KELLER, JEFFREY L., HADDAD JR, JOSEPH, MILJKOVIC, VLADAN, CATTORETTI, GIORGIO, CALIFANO, ANDREA, DALLA-FAVERA, RICCARDO

“…: The germinal center (GC) reaction in T cell dependent antibody responses is crucial for the generation of B cell memory and plays a critical role in B cell…”
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Report: workshop on mediastinal grey zone lymphoma by Poppema, Sibrand, Kluiver, Joost L, Atayar, Cigdem, van, den Berg, Anke, Rosenwald, Andreas, Hummel, Michael, Lenze, Dido, Lammert, Hetty, Stein, Harald, Joos, Stephan, Barth, Thomas, Dyer, Martin, Lichter, Peter, Klein, Uwe, Cattoretti, Giorgio, Gloghini, Annunziata, Tu, Yuhai, Stolovitzky, Gustavo A, Califano, Andrea, Carbone, Antonino, Dalla-Favera, Ricardo, Melzner, Ingo, Bucur, Alexandra J, Brüderlein, Silke, Dorsch, Karola, Hasel, Cornelia, Barth, Thomas FE, Leithäuser, Frank, Möller, Peter

“…:  There are several indications that classical Hodgkin lymphoma (cHL) and at least a proportion of cases of Primary Mediastinal B cell Lymphoma (PMBL) are…”
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Tracking CD40 Signaling during Normal Germinal Center Development by Gene Expression Profiling by BASSO, KATIA, KLEIN, ULF, NIU, HUIFENG, STOLOVITZKY, GUSTAVO A., TU, YUHAI, CALIFANO, ANDREA, CATTORETTI, GIORGIO, DALLA-FAVERA, RICCARDO

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