Search Results - "Stolarz, Amanda J."

Opinion: Endothelial Cells - Macrophage-Like Gatekeepers? by Stolarz, Amanda J, Mu, Shengyu, Zhang, Huiliang, Fouda, Abdelrahman Y, Rusch, Nancy J, Ding, Zufeng

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Doxorubicin Activates Ryanodine Receptors in Rat Lymphatic Muscle Cells to Attenuate Rhythmic Contractions and Lymph Flow by Stolarz, Amanda J, Sarimollaoglu, Mustafa, Marecki, John C, Fletcher, Terry W, Galanzha, Ekaterina I, Rhee, Sung W, Zharov, Vladimir P, Klimberg, V Suzanne, Rusch, Nancy J

“…Doxorubicin is a risk factor for secondary lymphedema in cancer patients exposed to surgery or radiation. The risk is presumed to relate to its cytotoxicity…”
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Liposome Formulation for Tumor-Targeted Drug Delivery Using Radiation Therapy by Stolarz, Amanda J, Chhetri, Bijay P, Borrelli, Michael J, Jenkins, Samir V, Jamshidi-Parsian, Azemat, Phillips, Joshua H, Fologea, Daniel, Gandy, Jay, Griffin, Robert J

“…Targeted delivery of drugs or other therapeutic agents through internal or external triggers has been used to control and accelerate the release from liposomal…”
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Drug-Related Lymphedema: Mysteries, Mechanisms, and Potential Therapies by Pal, Soumiya, Rahman, Jenat, Mu, Shengyu, Rusch, Nancy J, Stolarz, Amanda J

“…The lymphatic circulation is an important component of the circulatory system in humans, playing a critical role in the transport of lymph fluid containing…”
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Dantrolene Prevents the Lymphostasis Caused by Doxorubicin in the Rat Mesenteric Circulation by Van, Serena, Pal, Soumiya, Garner, Brittney R, Steed, Kate, Sridharan, Vijayalakshmi, Mu, Shengyu, Rusch, Nancy J, Stolarz, Amanda J

“…Doxorubicin (DOX) is a risk factor for arm lymphedema in breast cancer patients. We reported that DOX opens ryanodine receptors (RYRs) to enact "calcium leak,"…”
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Hypertension Induces Contractile Dysfunction in Rat Mesenteric Lymph Vessels by Pal, Soumiya, Henry, David, Rhee, Sung W., Stolarz, Amanda J.

“…Hypertension predisposes patients to a cluster of deadly cardiovascular and metabolic diseases involving inflammation, dyslipidemia, and fluid imbalance…”
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Real-Time Evaluation of Absolute, Cytosolic, Free Ca2+ and Corresponding Contractility in Isolated, Pressurized Lymph Vessels by Pal, Soumiya, Bagchi, Ashim K, Stolarz, Amanda J

“…The lymphatic vasculature, now often referred to as "the third circulation," is located in many vital organ systems. A principal mechanical function of the…”
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Rhythmic Contractions of Lymph Vessels and Lymph Flow Are Disrupted in Hypertensive Rats by Pal, Soumiya, Bagchi, Ashim K., Henry, David S., Landes, Reid D., Mu, Shengyu, Rhee, Sung W., Rusch, Nancy J., Stolarz, Amanda J.

“…BACKGROUND: Hypertension increases the risk of lymphedema in patients with comorbidities, but whether hypertension directly compromises lymph vessel (LV)…”
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KATP Channel Openers Inhibit Lymphatic Contractions and Lymph Flow as a Possible Mechanism of Peripheral Edema by Garner, Brittney R., Stolarz, Amanda J., Stuckey, Daniel, Sarimollaoglu, Mustafa, Liu, Yunmeng, Palade, Philip T., Rusch, Nancy J., Mu, Shengyu

“…Pharmacological openers of ATP-sensitive potassium (K ATP ) channels are effective antihypertensive agents, but off-target effects, including severe peripheral…”
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K ATP Channel Openers Inhibit Lymphatic Contractions and Lymph Flow as a Possible Mechanism of Peripheral Edema by Garner, Brittney R, Stolarz, Amanda J, Stuckey, Daniel, Sarimollaoglu, Mustafa, Liu, Yunmeng, Palade, Philip T, Rusch, Nancy J, Mu, Shengyu

“…Pharmacological openers of ATP-sensitive potassium (K ) channels are effective antihypertensive agents, but off-target effects, including severe peripheral…”
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Calcium Channel Blockers and Risk of Lymphedema among Breast Cancer Patients: Nested Case-Control Study by Stolarz, Amanda J, Lakkad, Mrinmayee, Klimberg, V Suzanne, Painter, Jacob T

“…To assess the risk of lymphedema associated with the use of calcium channel blockers (CCB) among breast cancer patients. A nested case-control study of adult…”
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Gender Differences in Cardiovascular Drugs by Stolarz, Amanda J., Rusch, Nancy J.

“…The different responses of women and men to cardiovascular drugs reflect gender –specific variances in pharmacokinetic profiles and drug sensitivities coupled…”
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High‐speed microscopy for in vivo monitoring of lymph dynamics by Sarimollaoglu, Mustafa, Stolarz, Amanda J., Nedosekin, Dmitry A., Garner, Brittney R., Fletcher, Terry W., Galanzha, Ekaterina I., Rusch, Nancy J., Zharov, Vladimir P.

“…The lymphatic system contributes to body homeostasis by clearing fluid, lipids, plasma proteins and immune cells from the interstitial space. Many studies have…”
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Fenofibrate Attenuates Neutrophilic Inflammation in Airway Epithelia: Potential Drug Repurposing for Cystic Fibrosis by Stolarz, Amanda J., Farris, Ryan A., Wiley, Charla A., O'Brien, Catherine E., Price, Elvin T.

“…A hallmark of cystic fibrosis (CF) lung disease is neutrophilic airway inflammation. Elevated neutrophil counts have been associated with decreased forced…”
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Contribution of the Renal Lymphatic Circulation to the Development of Salt‐Sensitive Hypertension by Garner, Brittney R, Stolarz, Amanda J, Rusch, Nancy J, Mu, Shengyu

“…More than one billion people worldwide suffer from hypertension, which is a leading cause of stroke and cardiovascular disease. According to the National…”
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ATP‐Sensitive K + Channels in Smooth Muscle Cells from Rat Mesenteric Lymph Vessels VESSELS by Garner, Brittney R., Stolarz, Amanda J., Fletcher, Terry W., Rusch, Nancy J.

“…The ATP‐sensitive potassium (K ATP ) channel is expressed in plasma membranes of many types of smooth muscle cells (SMCs). It is disinhibited when…”
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Characterization of a surgical model of lymphatic insufficiency in the rat mesentery by Stolarz, Amanda J, Garner, Brittney R, Fletcher, Terry W, Sarimollaoglu, Mustafa, Galanzha, Ekaterina, Zharov, Vladimir, Rusch, Nancy J

“…Abstract only The mesenteric lymphatic system clears fluid, lipids, plasma proteins, and immune cells from the intestinal interstitial space, thereby…”
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Doxorubicin Acutely Inhibits Lymph Flow in Rat Mesenteric Lymph Vessels by Stolarz, Amanda J, Fletcher, Terry W, Marecki, John C, Sarimollaoglu, Mustafa, Galanzha, Ekaterina, Zharov, Vladimir, Klimberg, Suzanne, Rusch, Nancy J

“…Abstract only Arm lymphedema is a major complication after surgery and/or radiation for breast cancer. This life‐long and disfiguring complication can cause…”
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Doxorubicin Inhibition of Lymphatic Function and Prevention by Dantrolene by Stolarz, Amanda J

“…Cancer-related lymphedema is an accumulation of protein-rich fluid in the interstitial tissue, which results from compromised lymphatic drainage associated…”
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