Search Results - "Stokes, Tanner"
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Resistance Exercise Training as a Primary Countermeasure to Age-Related Chronic Disease
Published in Frontiers in physiology (06-06-2019)“…Age is a primary risk factor for a number of chronic diseases including mobility disability, cardiovascular disease (CVD), type 2 diabetes (T2D), and cancer…”
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2
Recent Perspectives Regarding the Role of Dietary Protein for the Promotion of Muscle Hypertrophy with Resistance Exercise Training
Published in Nutrients (07-02-2018)“…Skeletal muscle supports locomotion and serves as the largest site of postprandial glucose disposal; thus it is a critical organ for physical and metabolic…”
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3
The impact of exercise and nutrition on the regulation of skeletal muscle mass
Published in The Journal of physiology (01-03-2019)“…The maintenance of skeletal muscle mass and strength throughout life is a key determinant of human health and well‐being. There is a gradual loss of both…”
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Recent advances in understanding resistance exercise training-induced skeletal muscle hypertrophy in humans [version 1; peer review: 2 approved]
Published in F1000 research (2020)“…Skeletal muscle plays a pivotal role in the maintenance of physical and metabolic health and, critically, mobility. Accordingly, strategies focused on…”
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5
Transcriptomic links to muscle mass loss and declines in cumulative muscle protein synthesis during short‐term disuse in healthy younger humans
Published in The FASEB journal (01-09-2021)“…Muscle disuse leads to a rapid decline in muscle mass, with reduced muscle protein synthesis (MPS) considered the primary physiological mechanism. Here, we…”
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6
Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States
Published in Cell reports (Cambridge) (04-08-2020)“…Loading of skeletal muscle changes the tissue phenotype reflecting altered metabolic and functional demands. In humans, heterogeneous adaptation to loading…”
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7
Declines in muscle protein synthesis account for short‐term muscle disuse atrophy in humans in the absence of increased muscle protein breakdown
Published in Journal of cachexia, sarcopenia and muscle (01-08-2022)“…Background We determined the short‐term (i.e. 4 days) impacts of disuse atrophy in relation to muscle protein turnover [acute fasted‐fed muscle protein…”
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Metabolic Perturbations from Step Reduction in Older Persons at Risk for Sarcopenia: Plasma Biomarkers of Abrupt Changes in Physical Activity
Published in Metabolites (08-07-2019)“…Sarcopenia is the age-related loss of skeletal muscle mass, strength and function, which may be accelerated during periods of physical inactivity. Declines in…”
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Understanding the effects of nutrition and post-exercise nutrition on skeletal muscle protein turnover: Insights from stable isotope studies
Published in Clinical nutrition open science (01-04-2021)“…Skeletal muscle is the largest organ of the human body and plays a pivotal role in whole-body homeostasis through the maintenance of physical and metabolic…”
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10
Transcriptomics for Clinical and Experimental Biology Research: Hang on a Seq
Published in Genetics & genomics next (01-06-2023)“…Sequencing the human genome empowers translational medicine, facilitating transcriptome‐wide molecular diagnosis, pathway biology, and drug repositioning…”
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11
The effect of oral essential amino acids on incretin hormone production in youth and ageing
Published in Endocrinology, diabetes & metabolism (01-10-2019)“…Background The effect of substantive doses of essential amino acids (EAA) on incretin and insulin production, and the impact of age upon this effect, is…”
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12
Dairy and Dairy Alternative Supplementation Increase Integrated Myofibrillar Protein Synthesis Rates, and Are Further Increased when Combined with Walking in Healthy Older Women
Published in The Journal of nutrition (01-01-2022)“…The stimulation of muscle protein synthesis (MPS) by dietary protein is reduced with age. We hypothesized that twice-daily milk consumption would increase…”
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13
Failed Recovery of Glycemic Control and Myofibrillar Protein Synthesis With 2 wk of Physical Inactivity in Overweight, Prediabetic Older Adults
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (09-07-2018)“…Physical inactivity impairs insulin sensitivity, which is exacerbated with aging. We examined the impact of 2 wk of acute inactivity and recovery on glycemic…”
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14
The effect of sleep restriction, with or without high‐intensity interval exercise, on myofibrillar protein synthesis in healthy young men
Published in The Journal of physiology (01-04-2020)“…Key points Sleep restriction has previously been associated with the loss of muscle mass in both human and animal models. The rate of myofibrillar protein…”
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15
Resistance‐only and concurrent exercise induce similar myofibrillar protein synthesis rates and associated molecular responses in moderately active men before and after training
Published in The FASEB journal (01-01-2024)“…Aerobic and resistance exercise (RE) induce distinct molecular responses. One hypothesis is that these responses are antagonistic and unfavorable for the…”
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16
Only Two Weeks of Physical Inactivity Induces Insulin Resistance and Impairs Glycemic Control in Older Adults
Published in The FASEB journal (01-04-2016)“…Abstract only Periods of physical inactivity are known to result in deleterious consequences for skeletal muscle mass, strength, and insulin sensitivity. We…”
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Two Weeks of Reduced Steps Disrupts Integrated Rates of Muscle Protein Synthesis and Glycemic Control in Healthy Older Adults
Published in The FASEB journal (01-04-2017)“…Transient periods of physical inactivity can result in losses of skeletal muscle mass and reductions in insulin sensitivity. These metabolic impairments may…”
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Exercise mitigates sleep-loss-induced changes in glucose tolerance, mitochondrial function, sarcoplasmic protein synthesis, and diurnal rhythms
Published in Molecular metabolism (Germany) (01-01-2021)“…Sleep loss has emerged as a risk factor for the development of impaired glucose tolerance. The mechanisms underpinning this observation are unknown; however,…”
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19
Methodological considerations for and validation of the ultrasonographic determination of human skeletal muscle hypertrophy and atrophy
Published in Physiological reports (01-01-2021)“…Magnetic resonance imaging (MRI) is the current gold standard for measuring changes in muscle size (cross‐sectional area [CSA] and volume) but can be…”
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Nutritional intervention to enhance recovery after arthroscopic knee surgery in adults: a randomized controlled pilot trial
Published in Pilot and feasibility studies (12-11-2024)“…Essential amino acid (EAA) and omega-3 fatty acid ingestion independently attenuate leg skeletal muscle disuse atrophy in uninjured persons. However, no data…”
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