Search Results - "Stokes, John B."

Prevalence and Correlates of Cognitive Impairment in Hemodialysis Patients: The Frequent Hemodialysis Network Trials by Kurella Tamura, Manjula, Larive, Brett, Unruh, Mark L, Stokes, John B, Nissenson, Allen, Mehta, Ravindra L, Chertow, Glenn M

“…Cognitive impairment is common among persons with ESRD, but the underlying mechanisms are unknown. This study evaluated the prevalence of cognitive impairment…”
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Effect of More Frequent Hemodialysis on Cognitive Function in the Frequent Hemodialysis Network Trials by Kurella Tamura, Manjula, MD, MPH, Unruh, Mark L., MD, MSc, Nissenson, Allen R., MD, Larive, Brett, MS, Eggers, Paul W., PhD, Gassman, Jennifer, PhD, Mehta, Ravindra L., MD, Kliger, Alan S., MD, Stokes, John B., MD

“…Background Cognitive impairment is common in patients with end-stage renal disease receiving hemodialysis 3 times per week. Study Design Randomized clinical…”
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Effects of Frequent Hemodialysis on Ventricular Volumes and Left Ventricular Remodeling by Chan, Christopher T, Greene, Tom, Chertow, Glenn M, Kliger, Alan S, Stokes, John B, Beck, Gerald J, Daugirdas, John T, Kotanko, Peter, Larive, Brett, Levin, Nathan W, Mehta, Ravindra L, Rocco, Michael, Sanz, Javier, Yang, Phillip C, Rajagopalan, Sanjay

“…Higher left ventricular volume is associated with death in patients with ESRD. This work investigated the effects of frequent hemodialysis on ventricular…”
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Effects of frequent hemodialysis on blood pressure: Results from the randomized frequent hemodialysis network trials by Kotanko, Peter, Garg, Amit X., Depner, Tom, Pierratos, Andreas, Chan, Christopher T., Levin, Nathan W., Greene, Tom, Larive, Brett, Beck, Gerald J., Gassman, Jennifer, Kliger, Alan S., Stokes, John B.

“…Hypertension is a common complication of chronic kidney disease and persists among most patients with end‐stage renal disease despite the provision of…”
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Recruitment and Training for Home Hemodialysis: Experience and Lessons from the Nocturnal Dialysis Trial by Pipkin, Mary, Eggers, Paul W, Larive, Brett, Rocco, Michael V, Stokes, John B, Suri, Rita S, Lockridge, Jr, Robert S

“…We assessed perceived barriers and incentives to home hemodialysis and evaluated potential correlates with the duration of home hemodialysis training. Surveys…”
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Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2 by Shi, Peijun P, Cao, Xiao R, Sweezer, Eileen M, Kinney, Thomas S, Williams, Nathan R, Husted, Russell F, Nair, Ramesh, Weiss, Robert M, Williamson, Roger A, Sigmund, Curt D, Snyder, Peter M, Staub, Olivier, Stokes, John B, Yang, Baoli

“…Nedd4-2 has been proposed to play a critical role in regulating epithelial Na+ channel (ENaC) activity. Biochemical and overexpression experiments suggest that…”
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The assessment, serial evaluation, and subsequent sequelae of acute kidney injury (ASSESS-AKI) study: design and methods by Go, Alan S, Parikh, Chirag R, Ikizler, T Alp, Coca, Steven, Siew, Edward D, Chinchilli, Vernon M, Hsu, Chi-Yuan, Garg, Amit X, Zappitelli, Michael, Liu, Kathleen D, Reeves, W Brian, Ghahramani, Nasrollah, Devarajan, Prasad, Faulkner, Georgia Brown, Tan, Thida C, Kimmel, Paul L, Eggers, Paul, Stokes, John B

“…The incidence of acute kidney injury (AKI) has been increasing over time and is associated with a high risk of short-term death. Previous studies on…”
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Nedd4-2 Modulates Renal Na+-Cl― Cotransporter via the Aldosterone-SGK1-Nedd4-2 Pathway by PABLO ARROYO, Juan, LAGNAZ, Dagmara, STOKES, John B, HOOVER, Robert S, GAMBA, Gerardo, STAUB, Olivier, RONZAUD, Caroline, VAZQUEZ, Norma, KO, Benjamin S, MODDES, Lauren, RUFFIEUX-DAIDIE, Dorothée, HAUSEL, Pierrette, KOESTERS, Robert, YANG, Baoli

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Heme transport exhibits polarity in Caco-2 cells: evidence for an active and membrane protein-mediated process by Uc, Aliye, Stokes, John B, Britigan, Bradley E

“…Heme prosthetic groups are vital for all living organisms, but they can also promote cellular injury by generating reactive oxygen species. Therefore,…”
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Discordant effects of corticosteroids and expression of subunits on ENaC activity by Husted, Russell F, Volk, Kenneth A, Sigmund, Rita D, Stokes, John B

“…In renal distal nephron and airway epithelial cells, adrenocortical steroids increase epithelial Na+ channel (ENaC) activity and also markedly increase the…”
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Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension by Ronzaud, Caroline, Loffing-Cueni, Dominique, Hausel, Pierrette, Debonneville, Anne, Malsure, Sumedha Ram, Fowler-Jaeger, Nicole, Boase, Natasha A, Perrier, Romain, Maillard, Marc, Yang, Baoli, Stokes, John B, Koesters, Robert, Kumar, Sharad, Hummler, Edith, Loffing, Johannes, Staub, Olivier

“…The E3 ubiquitin ligase NEDD4-2 (encoded by the Nedd4L gene) regulates the amiloride-sensitive epithelial Na+ channel (ENaC/SCNN1) to mediate Na+ homeostasis…”
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Regulation of rENaC mRNA by dietary NaCl and steroids: organ, tissue, and steroid heterogeneity by Stokes, J.B, Sigmund, R.D

“…Rats on a low-NaCl diet have a high Na+ channel activity in colon and kidney. To address the mechanism of this increased activity, we measured mRNA levels of…”
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Metabolism of haem in Caco-2 cells by Uc, Aliye, McDonagh, Antony F., Stokes, John B.

“…The haem oxygenase-1–biliverdin reductase system degrades haem and generates biliverdin and bilirubin, both of which possess antioxidant and…”
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Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway by Arroyo, Juan Pablo, Lagnaz, Dagmara, Ronzaud, Caroline, Vázquez, Norma, Ko, Benjamin S, Moddes, Lauren, Ruffieux-Daidié, Dorothée, Hausel, Pierrette, Koesters, Robert, Yang, Baoli, Stokes, John B, Hoover, Robert S, Gamba, Gerardo, Staub, Olivier

“…Regulation of renal Na(+) transport is essential for controlling blood pressure, as well as Na(+) and K(+) homeostasis. Aldosterone stimulates Na(+)…”
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Nephrogenic diabetes insipidus in mice caused by deleting COOH-terminal tail of aquaporin-2 by Shi, Peijun P, Cao, Xiao R, Qu, Jing, Volk, Ken A, Kirby, Patricia, Williamson, Roger A, Stokes, John B, Yang, Baoli

“…In mammals, the hormonal regulation of water homeostasis is mediated by the aquaporin-2 water channel (Aqp2) of the collecting duct (CD). Vasopressin induces…”
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Effects of daily hemodialysis on heart rate variability: results from the Frequent Hemodialysis Network (FHN) Daily Trial by Chan, Christopher T, Chertow, Glenn M, Daugirdas, John T, Greene, Tom H, Kotanko, Peter, Larive, Brett, Pierratos, Andreas, Stokes, John B

“…End-stage renal disease is associated with reduced heart rate variability (HRV), components of which generally are associated with advanced age, diabetes…”
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Nocturnal Hemodialysis: Analysis Following the Frequent Hemodialysis Network Trial by Stokes, John B.

“…The recently concluded Frequent Hemodialysis Network (FHN) trials have demonstrated some striking and unexpected results. Both the daily arm and the nocturnal…”
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Design of Clinical Trials in Acute Kidney Injury: Report from an NIDDK Workshop on Trial Methodology by Palevsky, Paul M, Molitoris, Bruce A, Okusa, Mark D, Levin, Adeera, Waikar, Sushrut S, Wald, Ron, Chertow, Glenn M, Murray, Patrick T, Parikh, Chirag R, Shaw, Andrew D, Go, Alan S, Faubel, Sarah G, Kellum, John A, Chinchilli, Vernon M, Liu, Kathleen D, Cheung, Alfred K, Weisbord, Steven D, Chawla, Lakhmir S, Kaufman, James S, Devarajan, Prasad, Toto, Robert M, Hsu, Chi-yuan, Greene, Tom, Mehta, Ravindra L, Stokes, John B, Thompson, Aliza M, Thompson, B Taylor, Westenfelder, Christof S, Tumlin, James A, Warnock, David G, Shah, Sudhir V, Xie, Yining, Duggan, Emily G, Kimmel, Paul L, Star, Robert A

“…Acute kidney injury (AKI) remains a complex clinical problem associated with significant short-term morbidity and mortality and lacking effective pharmacologic…”
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Determinants of Left Ventricular Mass in Patients on Hemodialysis: Frequent Hemodialysis Network (FHN) Trials by CHAN, Christopher T, GREENE, Tom, MEHTA, Ravindra L, ROCCO, Michael, SANZ, Javier, SCHILLER, Brigitte M, YANG, Phillip C, RAJAGOPALAN, Sanjay, CHERTOW, Glenn M, KLIGER, Alan S, STOKES, John B, BECK, Gerald J, DAUGIRDAS, John T, KOTANKO, Peter, LARIVE, Brett, LEVIN, Nathan W

“…An increase in left ventricular mass (LVM) is associated with mortality and cardiovascular morbidity in patients with end-stage renal disease. The Frequent…”
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Hormonal regulation of energy-protein homeostasis in hemodialysis patients: an anorexigenic profile that may predispose to adverse cardiovascular outcomes by Suneja, Manish, Murry, Daryl J, Stokes, John B, Lim, Victoria S

“…To assess whether endocrine dysfunction may cause derangement in energy homeostasis in patients undergoing hemodialysis (HD), we profiled hormones, during a…”
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