Search Results - "Stokes, Jayme B"

Preoperative Capecitabine and Concurrent Radiation for Borderline Resectable Pancreatic Cancer by Stokes, Jayme B., Nolan, Norris J., Stelow, Edward B., Walters, Dustin M., Weiss, Geoffrey R., de Lange, Eduard E., Rich, Tyvin A., Adams, Reid B., Bauer, Todd W.

“…Background Patients with borderline resectable pancreatic ductal adenocarcinoma (PDA) represent a high-risk group of patients due to tumor or patient-related…”
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Clinical, molecular and genetic validation of a murine orthotopic xenograft model of pancreatic adenocarcinoma using fresh human specimens by Walters, Dustin M, Stokes, Jayme B, Adair, Sara J, Stelow, Edward B, Borgman, Cheryl A, Lowrey, Bryce T, Xin, Wenjun, Blais, Edik M, Lee, Jae K, Papin, Jason A, Parsons, J Thomas, Bauer, Todd W

“…Relevant preclinical models that recapitulate the key features of human pancreatic ductal adenocarcinoma (PDAC) are needed in order to provide biologically…”
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Inhibition of the Growth of Patient-Derived Pancreatic Cancer Xenografts with the MEK Inhibitor Trametinib Is Augmented by Combined Treatment with the Epidermal Growth Factor Receptor/HER2 Inhibitor Lapatinib by Walters, Dustin M, Lindberg, James M, Adair, Sara J, Newhook, Timothy E, Cowan, Catharine R, Stokes, Jayme B, Borgman, Cheryl A, Stelow, Edward B, Lowrey, Bryce T, Chopivsky, Maria E, Gilmer, Tona M, Parsons, John T, Bauer, Todd W

“…Abstract Mutations of the oncogene KRAS are important drivers of pancreatic cancer progression. Activation of epidermal growth factor receptor (EGFR) and human…”
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Patients With Merkel Cell Carcinoma Tumors ≤ 1.0 cm in Diameter Are Unlikely to Harbor Regional Lymph Node Metastasis by STOKES, Jayme B, GRAW, Katherine S, DENGEL, Lynn T, SWENSON, Brian R, BAUER, Todd W, SLINGLUFF, Craig L, LEDESMA, Elihu J

“…Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine cutaneous malignancy. Current recommendations include offering regional lymph node evaluation…”
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Minimally invasive surgery fellowship does not adversely affect general surgery resident case volume: a decade of experience by Hallowell, Peter T., M.D, Dahman, Mohamed I., M.D, Stokes, Jayme B., M.D, LaPar, Damien J., M.D., M.Sc, Schirmer, Bruce D., M.D

“…Abstract Background With the advent of clinical fellowships in general surgery, there has been a continual debate over the effect on general surgical resident…”
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Surgical Management of Hepatic Neuroendocrine Tumor Metastasis: Results from an International Multi-Institutional Analysis by Mayo, Skye C., de Jong, Mechteld C., Pulitano, Carlo, Clary, Brian M., Reddy, Srinevas K., Gamblin, T. Clark, Celinksi, Scott A., Kooby, David A., Staley, Charles A., Stokes, Jayme B., Chu, Carrie K., Ferrero, Alessandro, Schulick, Richard D., Choti, Michael A., Mentha, Giles, Strub, Jennifer, Bauer, Todd W., Adams, Reid B., Aldrighetti, Luca, Capussotti, Lorenzo, Pawlik, Timothy M.

“…Background Management of neuroendocrine tumor liver metastasis (NELM) remains controversial, with some advocating an aggressive surgical approach while others…”
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Inhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment by Stokes, Jayme B, Adair, Sara J, Slack-Davis, Jill K, Walters, Dustin M, Tilghman, Robert W, Hershey, E Dan, Lowrey, Bryce, Thomas, Keena S, Bouton, Amy H, Hwang, Rosa F, Stelow, Edward B, Parsons, J Thomas, Bauer, Todd W

“…Current therapies for pancreatic ductal adenocarcinoma (PDA) target individual tumor cells. Focal adhesion kinase (FAK) is activated in PDA, and levels are…”
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Proactive versus reactive: the effect of experience on performance in a critical care simulator by Young, Jeffrey S., M.D, Stokes, Jayme B., M.D, Denlinger, Chadrick E., M.D, Dubose, Joseph E., M.D

“…Abstract Background We sought to study the cognitive performance of residents in a critical care patient simulator. Methods Residents in general surgery and…”
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Surgery Versus Intra-arterial Therapy for Neuroendocrine Liver Metastasis: A Multicenter International Analysis by Mayo, Skye C., de Jong, Mechteld C., Bloomston, Mark, Pulitano, Carlo, Clary, Bryan M., Reddy, Srinevas K., Clark Gamblin, T., Celinski, Scott A., Kooby, David A., Staley, Charles A., Stokes, Jayme B., Chu, Carrie K., Arrese, David, Ferrero, Alessandro, Schulick, Richard D., Choti, Michael A., Geschwind, Jean-Francois H., Strub, Jennifer, Bauer, Todd W., Adams, Reid B., Aldrighetti, Luca, Mentha, Gilles, Capussotti, Lorenzo, Pawlik, Timothy M.

“…Background Management of patients with neuroendocrine liver metastasis (NELM) remains controversial. We sought to examine the relative efficacy of surgical…”
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Pancreas-Protocol Imaging at a High-Volume Center Leads to Improved Preoperative Staging of Pancreatic Ductal Adenocarcinoma by Walters, Dustin M., LaPar, Damien J., de Lange, Eduard E., Sarti, Marc, Stokes, Jayme B., Adams, Reid B., Bauer, Todd W.

“…Background High-quality preoperative cross-sectional imaging is vital to accurately stage patients with pancreatic ductal adenocarcinoma (PDAC). We…”
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Use of a falciform ligament pedicle flap to decrease pancreatic fistula after distal pancreatectomy by Walters, Dustin M, Stokes, Jayme B, Adams, Reid B, Bauer, Todd W

“…Postoperative pancreatic fistula (POPF) remains a significant source of morbidity after distal pancreatectomy (DP). We describe a technique for coverage of the…”
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Adrenalectomy for adrenal-mediated hypertension: National Surgical Quality Improvement Program analysis of an institutional experience by Shada, Amber L, Stokes, Jayme B, Turrentine, Florence E, Simpson, Virginia B, Padia, Shetal H, Carey, Robert M, Hanks, John B, Smith, Philip W

“…Adrenal-mediated hypertension (AMH) has been increasingly treated by laparoscopic adrenalectomy (LA). Metabolic derangements in patients with AMH could result…”
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Donor risk index predicts graft failure reliably but not post-transplant infections by Rosenberger, Laura H, Gillen, Jacob R, Hranjec, Tjasa, Stokes, Jayme B, Brayman, Kenneth L, Kumer, Sean C, Schmitt, Timothy M, Sawyer, Robert G

“…The Donor Risk Index (DRI) is used to predict graft survival following liver transplantation, but has not been used to predict post-operative infections in…”
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Laparoscopic Ventral Hernia Repair: Mesh Options and Outcomes by Stokes, Jayme B., MD, Friel, Charles M., MD

“…Laparoscopic ventral hernia repair (LVHR) offers a minimally invasive option for the repair of congenital or incisional abdominal wall hernias. A key component…”
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Surgical Management of Hepatic Neuroendocrine Tumor Metastasis: Results from an International Multi-Institutional Analysis by Mayo, Skye C., de Jong, Mechteld C., Pulitano, Carlo, Clary, Brian M., Reddy, Srinevas K., Gamblin, T. Clark, Celinksi, Scott A., Kooby, David A., Staley, Charles A., Stokes, Jayme B., Chu, Carrie K., Ferrero, Alessandro, Schulick, Richard D., Choti, Michael A., Mentha, Giles, Strub, Jennifer, Bauer, Todd W., Adams, Reid B., Aldrighetti, Luca, Capussotti, Lorenzo, Pawlik, Timothy M.

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Abstract 5600: Acquired resistance of pancreatic cancers to combination therapy with lapatinib plus the MEK 1/2 inhibitor GSK1120212: Using a murine orthotopic xenograft model to identify resistance pathways by Lindberg, James M., Walters, Dustin M., Adair, Sara J., Xin, Wenjun, Edik, Blais, Stokes, Jayme B., Borgman, Cheryl A., Stelow, Edward B., Sanoff, Hanna K., Lee, Jae K., Papin, Jason A., Parsons, J. Thomas, Bauer, Todd W.

“…Abstract Background: The high incidence of KRAS mutations in human pancreatic cancers has driven the testing of MEK1/2 inhibitors (e.g. GSK1120212) in clinical…”
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Abstract LB-241: Cancer-associated fibroblasts modulate growth- and metastasis-promoting pathways in human pancreatic cancer cells and augment orthotopic tumor growth in mice by Walters, Dustin M., Adair, Sara J., Stokes, Jayme B., Lowrey, Bryce, Parsons, J. Thomas, Bauer, Todd W.

“…Abstract Background: The role of cancer-associated fibroblasts (CAFs) in the development, progression, and metastasis of pancreatic ductal adenocarcinoma…”
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Acquired resistance to combination therapy with lapatinib and MEK 1/2 inhibitor GSK1120212 in an in vivo murine model of pancreatic cancer by Lindberg, James M., Walters, Dustin M, Adair, Sara J, Cowan, Catharine R, Stokes, Jayme B, Borgman, Cheryl A, Stelow, Edward B, Lowrey, Bryce T, Chopivsky, Maria E, Parsons, J Thomas, Bauer, Todd W.

“…Abstract only 208 Background: Mutations of the oncogene KRAS and activation of cell-surface receptor tyrosine kinases are important and preserved mechanisms of…”
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Inhibition of the Growth of Patient-Derived Pancreatic Cancer Xenografts with the MEK Inhibitor Trametinib Is Augmented by Combined Treatment with the Epidermal Growth Factor Receptor/HER2 Inhibitor Lapatinib12 by Walters, Dustin M, Lindberg, James M, Adair, Sara J, Newhook, Timothy E, Cowan, Catharine R, Stokes, Jayme B, Borgman, Cheryl A, Stelow, Edward B, Lowrey, Bryce T, Chopivsky, Maria E, Gilmer, Tona M, Parsons, John T, Bauer, Todd W

“…Mutations of the oncogene KRAS are important drivers of pancreatic cancer progression. Activation of epidermal growth factor receptor (EGFR) and human EGFR2…”
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Abstract 1592: Targeting proliferative signals in patient-derived pancreatic cancers propagated orthotopically in immunocompromised mice by Walters, Dustin M., Cowan, Catharine R., Adair, Sara J., Borgman, Cheryl A., Stokes, Jayme B., Stelow, Edward B., Lowrey, Bryce T., Gilmer, Tona M., Parsons, J. Thomas, Bauer, Todd W.

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is associated with the shortest survival duration of any solid cancer. To improve treatment for this disease,…”
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