Search Results - "Stokes, G S"

A controlled study of the effects of isosorbide mononitrate on arterial blood pressure and pulse wave form in systolic hypertension by STOKES, G. S, RYAN, M, BRNABIC, A, NYBERG, G

“…To determine the effect of an extended-release nitrate preparation on the arterial pulse wave and blood pressure of patients in whom systolic blood pressure…”
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Comparison of the effects on urinary sodium excretion of indomethacin and of carbidopa in normal volunteers given an intravenous saline infusion by Stokes, G S, Monaghan, J C, Pillai, D N

“…1. Dopamine and prostaglandins are putative endogenous natriuretic hormones. The role of each in facilitating natriuresis induced by intravenous saline…”
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Double-blind crossover study of the interaction between perindopril and amlodipine on blood pressure and hormones related to fluid and electrolyte balance in patients with essential hypertension by STOKES, G. S, MONAGHAN, J. C, BERMAN, K, RYAN, M, CAMPBELL, D. J

“…This study was to investigate the interaction between low doses of perindopril (2 mg daily) and amlodipine (2.5 mg daily) on ambulatory blood pressure (BP),…”
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Influence of angiotensin converting enzyme (ACE) genotype on interpretation of diagnostic tests for serum ACE activity by Stokes, G. S., Monaghan, J. C., Schrader, A. P., Glenn, C. L., Ryan, M., Morris, B. J.

“…Background: The discovery that an insertion/deletion (I/D) polymorphism of the angiotensin converting enzyme (ACE) gene influences the circulating…”
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Diet modification in lowering plasma cholesterol levels. A randomised trial of three types of intervention by Johnston, H J, Jones, M, Ridler-Dutton, G, Spechler, F, Stokes, G S, Wyndham, L E

“…To compare the efficacy of three types of diet and lifestyle interventions for lowering plasma lipid levels. Randomised parallel-group trial. Adults with…”
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Effects of Isosorbide Mononitrate and AII Inhibition on Pulse Wave Reflection in Hypertension by Stokes, Gordon S, Barin, Edward S, Gilfillan, Kerry L

“…ABSTRACT—The aortic pulse wave contour in isolated systolic hypertension often shows a prominent reflection peak, which combines with the incident wave arising…”
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Optimum drug treatment in hypertension by Stokes, G S

“…The ultimate objective in treating hypertension is to select an agent directed at the specific mechanism causing blood pressure elevation in the individual…”
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Effects of carbidopa and of intravenous saline infusion into normal and hypertensive subjects on urinary free and conjugated dopamine by Stokes, Gordon S, Monaghan, Judith C, Pillai, Dilo N

“…OBJECTIVETo investigate the possible role played by endogenous dopamine as a modulator of renal sodium (Na) reabsorption after a combined Na and volume load…”
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Humoral determinants of Na+ excretion after intravenous NaCl loading in normal volunteers by Stokes, G S, Johnston, H J, Monaghan, J C

“…1. Twelve healthy volunteers maintained on a 100 mmol/day Na+ diet, were given an intravenous infusion of 2L saline (0.9%) between 10.00 h on 2 study days at…”
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Timing of blood pressure measurements in determining anomalies in duration of effect of an antihypertensive drug: assessment of isradipine by Stokes, G S, Shenfield, G M, Johnston, H J, Marwood, J F, Dunagan, F, Boutagy, J

“…Analysis of an antihypertensive drug trial, which involved measurements of blood pressure (BP) during visits to the clinic at a set time of day, showed that…”
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Studies that question the existence of alpha-2 adrenoceptors in tail arteries of normotensive Sprague-Dawley rats by Marwood, J F, Chapman, K L, Stokes, G S

“…Many pharmacological studies have demonstrated two distinct types of alpha adrenoceptor in the vasculature; these receptors have been named alpha-1 and…”
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Effects of oral contraceptives containing oestrogen combined with norethisterone or levonorgestrel on erythrocyte cation transport in normal women by Stokes, G S, Monaghan, J C, Flemming, C L, Johnston, H, Jones, M, Pinkerton, G, Baber, R

“…1. Studies were undertaken in pre-menopausal women to examine the effects of treatment with standard oestrogen-progestogen and progestogen-ony oral…”
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Age-related effects of antihypertensive therapy with alpha-blockers by Stokes, G S

“…Currently, the most important alpha-blockers used in treating hypertension are prazosin and its long-acting congeners, doxazosin and terazosin. Although there…”
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Comparative and combined efficacy of doxazosin and enalapril in hypertensive patients by Stokes, G S, Johnston, H J, Okoro, E O, Boutagy, J, Monaghan, J C, Marwood, J F

“…Twenty patients with essential hypertension were randomised to a 7-week period of dose titration with doxazosin, 1-8mg/day or enalapril, 5-20mg/day. In a…”
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Ketanserin and prazosin: a comparison of antihypertensive and biochemical effects by Stokes, G S, Mennie, B A, Marwood, J F

“…A randomized crossover trial was conducted in 15 patients with essential hypertension to compare the actions of prazosin, a specific alpha 1-adrenoceptor…”
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Adolescent Life Experiences as Predictors of Occupational Attainment by Snell, Andrea F, Stokes, Garnett S, Sands, Marjorie M, McBride, James R

“…Adolescent life experiences, measured with Owens's Biographical Questionnaire (BQ), were used to predict occupational attainment 16 years to 21 years later in…”
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Alpha blocking action of the antihypertensive agent, prazosin by Graham, R M, Oates, H F, Stoker, L M, Stokes, G S

“…The vasodilatory and alpha adrenergic blocking properties of prazosin were studied in anesthetized rats and compared with the direct-acting vasodilator,…”
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The pharmokinetics of isradipine in hypertensive subjects by SHENFIELD, G. M, BOUTAGY, J, STOKES, G. S, RUMBLE, F, DUNAGAN, F

“…In conjunction with a multicentre clinical trial of the calcium antagonist isradipine in hypertension, pharmacokinetic and pharmacodynamic studies were…”
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Effect of dialysis on circulating Na,K ATPase inhibitor in uremic patients by Stokes, G S, Norris, L A, Marwood, J F, Johnston, H, Caterson, R J

“…Deproteinized plasma from patients with renal failure had an inhibitory effect on Na,K ATPase activity measured in vitro by a linked-enzyme assay. No…”
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Genotypic influence on plasma dipeptidyl carboxypeptidase-1 activity in hypertensives by Morris, B J, Monaghan, J C, Perich, R, Stokes, G S, Jackson, B, Schrader, A P

“…1. Plasma dipeptidyl carboxypeptidase-1 (DCP1; angiotensin I-converting enzyme, kininase II; EC 3.4.15.1) tracks with the deletion allele in genotypes of a 287…”
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