Search Results - "Stokes, Elaine Se"

An industry perspective approach and control strategy for implementation of ready-to-use cells in bioassays: survey outcome and recommendations by White, John R, Ahmed, Sammina, Amstrup, Jan, Bennington, Petra, Cheng, Zhijie Jey, Day, Peter, Haenssen, Keneshia K, Kozminsky-Atias, Adi, Martinez, Eva, Ong, Esther Hq, Qahwash, Isam, Stokes, Elaine Se, Wang, Jenny

“…The BioPhorum Development Group is an industry collaboration enabling the sharing of common practices for the development of biopharmaceuticals. Bioassays are…”
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Best practices in bioassay development to support registration of biopharmaceuticals by White, John R, Abodeely, Marla, Ahmed, Sammina, Debauve, Gaël, Johnson, Evan, Meyer, Debra M, Mozier, Ned M, Naumer, Matthias, Pepe, Alessandra, Qahwash, Isam, Rocnik, Edward, Smith, Jeffrey G, Stokes, Elaine Se, Talbot, Jeffrey J, Wong, Pin Yee

“…Biological activity is a critical quality attribute for biopharmaceuticals, which is accurately measured using an appropriate relative potency bioassay…”
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Design and campaign synthesis of pyridine-based histone deacetylase inhibitors by Andrews, David M., Gibson, Keith M., Graham, Mark A., Matusiak, Zbigniew S., Roberts, Craig A., Stokes, Elaine S.E., Brady, Madeleine C., Chresta, Christine M.

“…The synthesis of the HDAC inhibitor 13b is reported. (HDAC1 enzyme pIC 50 8.01.) A lead benzamide, bearing a cyanopyridyl moiety ( 3), was identified as a…”
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Design and campaign synthesis of piperidine- and thiazole-based histone deacetylase inhibitors by Andrews, David M., Stokes, Elaine S.E., Carr, Greg R., Matusiak, Zbigniew S., Roberts, Craig A., Waring, Michael J., Brady, Madeleine C., Chresta, Christine M., East, Simon J.

“…The synthesis of the HDAC inhibitor 16d is reported. (HDAC1 enzyme pIC 50 7.46. A549a xenograft efficacy at 12.5 mg/kg.) A lead benzamide, 3, was identified as…”
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