Search Results - "Stojilkovic, S. S."

Activation and regulation of purinergic P2X receptor channels by Coddou, Claudio, Yan, Zonghe, Obsil, Tomas, Huidobro-Toro, J Pablo, Stojilkovic, Stanko S

“…Mammalian ATP-gated nonselective cation channels (P2XRs) can be composed of seven possible subunits, denoted P2X1 to P2X7. Each subunit contains a large…”
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Characterization of the antagonist actions of 5-BDBD at the rat P2X4 receptor by Coddou, Claudio, Sandoval, Rodrigo, Hevia, María José, Stojilkovic, Stanko S.

“…•We confirmed that 5-BDBD is a potent P2X4 receptor antagonist.•The selectivity of 5-BDBD allows to discriminate between P2X4 and other P2X subtypes.•5-BDBD…”
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PI(4,5)P2-dependent and -independent roles of PI4P in the control of hormone secretion by pituitary cells by Stojilkovic, Stanko S, Balla, Tamas

“…Plasma membrane and organelle membranes are home to seven phosphoinositides, an important class of low-abundance anionic signaling lipids that contribute to…”
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Dual Gating Mechanism and Function of P2X7 Receptor Channels by Khadra, Anmar, Tomić, Melanija, Yan, Zonghe, Zemkova, Hana, Sherman, Arthur, Stojilkovic, Stanko S.

“…The ATP-gated P2X7 receptor channel (P2X7R) operates as a cytolytic and apoptotic receptor but also controls sustained cellular responses, including cell…”
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Cell Type- and Sex-Dependent Transcriptome Profiles of Rat Anterior Pituitary Cells by Fletcher, Patrick A, Smiljanic, Kosara, Maso Prévide, Rafael, Iben, James R, Li, Tianwei, Rokic, Milos B, Sherman, Arthur, Coon, Steven L, Stojilkovic, Stanko S

“…Understanding the physiology and pathology of an organ composed of a variety of cell populations depends critically on genome-wide information on each cell…”
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Molecular mechanisms of pituitary endocrine cell calcium handling by Stojilkovic, Stanko S

“…Abstract Endocrine pituitary cells express numerous voltage-gated Na+ , Ca2+ , K+ , and Cl− channels and several ligand-gated channels, and they fire action…”
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Experimental characterization and mathematical modeling of P2X7 receptor channel gating by Yan, Zonghe, Khadra, Anmar, Li, Shuo, Tomic, Melanija, Sherman, Arthur, Stojilkovic, Stanko S

“…The P2X7 receptor is a trimeric channel with three binding sites for ATP, but how the occupancy of these sites affects gating is still not understood. Here we…”
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Common and female-specific roles of protein tyrosine phosphatase receptors N and N2 in mice reproduction by Sokanovic, Srdjan J., Constantin, Stephanie, Lamarca Dams, Aloa, Mochimaru, Yuta, Smiljanic, Kosara, Bjelobaba, Ivana, Prévide, Rafael M., Stojilkovic, Stanko S.

“…Simultaneous knockout of the neuroendocrine marker genes Ptprn and Ptprn2 , which encode the protein tyrosine phosphatase receptors N and N2, causes…”
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Ion Channels of Pituitary Gonadotrophs and Their Roles in Signaling and Secretion by Stojilkovic, Stanko S, Bjelobaba, Ivana, Zemkova, Hana

“…Gonadotrophs are basophilic cells of the anterior pituitary gland specialized to secrete gonadotropins in response to elevation in intracellular calcium…”
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Dependence of STIM1/Orai1-mediated Calcium Entry on Plasma Membrane Phosphoinositides by Korzeniowski, Marek K., Popovic, Marko A., Szentpetery, Zsofia, Varnai, Peter, Stojilkovic, Stanko S., Balla, Tamas

“…Recent studies identified two main components of store-operated calcium entry (SOCE): the endoplasmic reticulum-localized Ca2+ sensor protein, STIM1, and the…”
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Schwann-Cell-Specific Deletion of Phosphatidylinositol 4-Kinase Alpha Causes Aberrant Myelination by Alvarez-Prats, Alejandro, Bjelobaba, Ivana, Aldworth, Zane, Baba, Takashi, Abebe, Daniel, Kim, Yeun Ju, Stojilkovic, Stanko S., Stopfer, Mark, Balla, Tamas

“…Active membrane remodeling during myelination relies on phospholipid synthesis and membrane polarization, both of which are known to depend on inositol…”
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Deciphering the regulation of P2X4 receptor channel gating by ivermectin using Markov models by Mackay, Laurent, Zemkova, Hana, Stojilkovic, Stanko S, Sherman, Arthur, Khadra, Anmar

“…The P2X4 receptor (P2X4R) is a member of a family of purinergic channels activated by extracellular ATP through three orthosteric binding sites and…”
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Testicular steroidogenesis is suppressed during experimental autoimmune encephalomyelitis in rats by Milosevic, Ana, Bjelobaba, Ivana, Bozic, Iva D., Lavrnja, Irena, Savic, Danijela, Tesovic, Katarina, Jakovljevic, Marija, Stojilkovic, Stanko S., Janjic, Marija M.

“…Multiple sclerosis (MS) is an autoimmune disease that usually occurs during the reproductive years in both sexes. Many male patients with MS show lower blood…”
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Calcium-dependent block of P2X7 receptor channel function is allosteric by Yan, Zonghe, Khadra, Anmar, Sherman, Arthur, Stojilkovic, Stanko S

“…Among purinergic P2X receptor (P2XR) channels, the P2X7R exhibits the most complex gating kinetics; the binding of orthosteric agonists at the ectodomain…”
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Identification of functionally important residues of the rat P2X4 receptor by alanine scanning mutagenesis of the dorsal fin and left flipper domains by Tvrdonova, Vendula, Rokic, Milos B, Stojilkovic, Stanko S, Zemkova, Hana

“…Crystallization of the zebrafish P2X4 receptor in both open and closed states revealed conformational differences in the ectodomain structures, including the…”
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Role of domain calcium in purinergic P2X2 receptor channel desensitization by Coddou, Claudio, Yan, Zonghe, Stojilkovic, Stanko S

“…Activation of P2X2 receptor channels (P2X2Rs) is characterized by a rapid current growth accompanied by a decay of current during sustained ATP application, a…”
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Editorial: Gonadotropin-Releasing Hormone Receptor Signaling and Functions by Bjelobaba, Ivana, Stojilkovic, Stanko S, Naor, Zvi

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Intrinsic and Regulated Gonadotropin-Releasing Hormone Receptor Gene Transcription in Mammalian Pituitary Gonadotrophs by Janjic, Marija M, Stojilkovic, Stanko S, Bjelobaba, Ivana

“…The hypothalamic decapeptide gonadotropin-releasing hormone (GnRH), acting its receptors (GnRHRs) expressed in pituitary gonadotrophs, represents a critical…”
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Two open states of P2X receptor channels by Rokic, Milos B, Stojilkovic, Stanko S

“…The occupancy of the orthosteric ligand binding sites of P2X receptor (P2XR) channels causes the rapid opening of a small cation-permeable pore, followed by a…”
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Ca2+-regulated exocytosis and SNARE function by STOJILKOVIC, Stanko S

“…Secretory vesicles formed at the trans-Golgi network of neuroendocrine and endocrine cells must undergo several steps, such as translocation, docking and…”
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