Search Results - "Stojanović, Milan N"
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Aptamer-field-effect transistors overcome Debye length limitations for small-molecule sensing
Published in Science (American Association for the Advancement of Science) (19-10-2018)“…Detection of analytes by means of field-effect transistors bearing ligand-specific receptors is fundamentally limited by the shielding created by the…”
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Wearable aptamer-field-effect transistor sensing system for noninvasive cortisol monitoring
Published in Science advances (07-01-2022)“…Wearable technologies for personalized monitoring require sensors that track biomarkers often present at low levels. Cortisol—a key stress biomarker—is present…”
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Phenylalanine Monitoring via Aptamer-Field-Effect Transistor Sensors
Published in ACS sensors (27-12-2019)“…Determination of the amino acid phenylalanine is important for lifelong disease management in patients with phenylketonuria, a genetic disorder in which…”
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Cross-Reactive Arrays Based on Three-Way Junctions
Published in Journal of the American Chemical Society (21-05-2003)“…We report herein a novel system for the parallel processing of molecular recognition events utilizing arrays of oligonucleotide-based fluorescent sensors to…”
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Electrochemical Aptamer-Based Sensors for Improved Therapeutic Drug Monitoring and High-Precision, Feedback-Controlled Drug Delivery
Published in ACS sensors (25-10-2019)“…The electrochemical aptamer-based (E-AB) sensing platform appears to be a convenient (rapid, single-step, and calibration-free) and modular approach to measure…”
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6
Deoxyribozyme-Based Half-Adder
Published in Journal of the American Chemical Society (04-06-2003)“…We have constructed a solution-phase array of three deoxyribozyme-based logic gates that behaves as a half-adder. Two deoxyribozymes mimic i1ANDNOTi2 and…”
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Aptamer-Based Colorimetric Probe for Cocaine
Published in Journal of the American Chemical Society (21-08-2002)“…Complex of an anti-cocaine aptamer and the dye diethylthiotricarbocyanine behaves as a colorimetric sensor with attenuation in absorbance at 760 nm for cocaine…”
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Behavior of Polycatalytic Assemblies in a Substrate-Displaying Matrix
Published in Journal of the American Chemical Society (04-10-2006)“…We describe polycatalytic assemblies, comprising one or two streptavidin molecules and two to six attached nucleic acid catalysts (deoxyribozymes), with…”
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Integrated Microfluidic Isolation of Aptamers Using Electrophoretic Oligonucleotide Manipulation
Published in Scientific reports (24-05-2016)“…We present a microfluidic approach to integrated isolation of DNA aptamers via systematic evolution of ligands by exponential enrichment (SELEX). The approach…”
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Exercises in Molecular Computing
Published in Accounts of chemical research (17-06-2014)“…The successes of electronic digital logic have transformed every aspect of human life over the last half-century. The word “computer” now signifies a…”
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Amplification of Signal on Cell Surfaces in Molecular Cascades
Published in Cells (Basel, Switzerland) (01-12-2023)“…We can formulate mixtures of oligonucleotide-antibody conjugates to act as molecular cascade-based automata that analyze pairs of cell surface markers (CD…”
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Exploring the Landscape of Aptamers: From Cross-Reactive to Selective to Specific, High-Affinity Receptors for Cocaine
Published in JACS Au (26-02-2024)“…We reported over 20 years ago MNS-4.1, the first DNA aptamer with a micromolar affinity for cocaine. MNS-4.1 is based on a structural motif that is very common…”
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13
Light-up properties of complexes between thiazole orange-small molecule conjugates and aptamers
Published in Nucleic acids research (01-05-2009)“…The full understanding of dynamics of cellular processes hinges on the development of efficient and non-invasive labels for intracellular RNA species. Light-up…”
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14
Study of thiazole orange in aptamer-based dye-displacement assays
Published in Analytical and bioanalytical chemistry (01-02-2008)“…We screened a series of RNA and DNA aptamers for their ability to serve in the dye displacement assays in which analytes compete with TO dye. We conclude that,…”
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15
Hydrogel Microfilaments toward Intradermal Health Monitoring
Published in iScience (22-11-2019)“…Digital health promises a paradigm shift for medicine where biomarkers in individuals are continuously monitored to improve diagnosis and treatment of disease…”
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In vitro selection and amplification protocols for isolation of aptameric sensors for small molecules
Published in Methods (San Diego, Calif.) (15-08-2016)“…•Highly useful method for the selection of aptamers for small-molecule targets.•Provides a very detail step-wise guide to a selection protocol.•Simple enough…”
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17
Training a molecular automaton to play a game
Published in Nature nanotechnology (01-11-2010)“…Research at the interface between chemistry and cybernetics has led to reports of ‘programmable molecules’, but what does it mean to say ‘we programmed a set…”
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Oligonucleotide-Blocked Streptavidin for Biotinylation Analysis
Published in Bioconjugate chemistry (18-01-2023)“…Binding between streptavidin, or its homologues, to biotin is one of the most widely exploited biological interactions in the biomedical sciences. Controlling…”
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Molecular robots guided by prescriptive landscapes
Published in Nature (London) (13-05-2010)“…Traditional robots rely for their function on computing, to store internal representations of their goals and environment and to coordinate sensing and any…”
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A functional group-guided approach to aptamers for small molecules
Published in Science (American Association for the Advancement of Science) (02-06-2023)“…Aptameric receptors are important biosensor components, yet our ability to identify them depends on the target structures. We analyzed the contributions of…”
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