Search Results - "Stoffel, Marc"

An Investigation Into Local Infusion Site Pain After Infusion of Ultra Rapid Lispro Excipients Across Sites and Depths by Ignaut, Debra, Fukuda, Tsuyoshi, Bandi, Ramanjineyulu, Ermer, Marcel, Stoffel, Marc S., Zijlstra, Eric, Paavola, Chad

“…Background: This phase 1, randomized, one-day, five-period crossover study in adults with type 1 diabetes on continuous subcutaneous insulin infusion…”
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A HILIC-MS/MS assay for the quantification of metformin and sitagliptin in human plasma and urine: A tool for studying drug transporter perturbation by Scherf-Clavel, Oliver, Kinzig, Martina, Stoffel, Marc S., Fuhr, Uwe, Sörgel, Fritz

“…•Fast and accurate assay for plasma and urine.•Method for conducting drug-drug interactions studies.•Validation according to FDA guidelines.•Mini-Review of…”
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109-LB: An Investigation into Local Infusion Site Pain after Infusion of URLi Excipients across Sites and Depths by IGNAUT, DEBRA A., FUKUDA, TSUYOSHI, RAMANJINEYULU, BANDI, ERMER, MARCEL, STOFFEL, MARC S., ZIJLSTRA, ERIC, PAAVOLA, D

“…A Phase 1, randomized, 1-day 5-period crossover study in adults with type 1 diabetes on CSII investigated whether pain is dependent on the site and/or depth of…”
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Quantification of adefovir and pitavastatin in human plasma and urine by LC-MS/MS: A useful tool for drug-drug interaction studies by Scherf-Clavel, Oliver, Kinzig, Martina, Stoffel, Marc S., Fuhr, Uwe, Sörgel, Fritz

“…As a tool to be used in transporter-mediated drug-drug interaction studies, a sensitive LC-MS/MS method for the simultaneous quantification of adefovir and…”
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A Clinical Drug‐Drug Interaction Study Assessing a Novel Drug Transporter Phenotyping Cocktail With Adefovir, Sitagliptin, Metformin, Pitavastatin, and Digoxin by Trueck, Christina, Hsin, Chih‐hsuan, Scherf‐Clavel, Oliver, Schaeffeler, Elke, Lenssen, Rebekka, Gazzaz, Malaz, Gersie, Marleen, Taubert, Max, Quasdorff, Maria, Schwab, Matthias, Kinzig, Martina, Sörgel, Fritz, Stoffel, Marc S., Fuhr, Uwe

“…A new probe drug cocktail containing substrates of important drug transporters was tested for mutual interactions in a clinical trial. The cocktail consisted…”
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Combinations of common SNPs of the transporter gene ABCB1 influence apparent bioavailability, but not renal elimination of oral digoxin by Hsin, Chih-hsuan, Stoffel, Marc S., Gazzaz, Malaz, Schaeffeler, Elke, Schwab, Matthias, Fuhr, Uwe, Taubert, Max

“…Effects of different genotypes on the pharmacokinetics of probe substrates may support their use as phenotyping agents for the activity of the respective…”
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CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition by von Bergwelt-Baildon, Michael S., Popov, Alexey, Saric, Tomo, Chemnitz, Jens, Classen, Sabine, Stoffel, Marc S., Fiore, Francesca, Roth, Udo, Beyer, Marc, Debey, Svenja, Wickenhauser, Claudia, Hanisch, Franz-Georg, Schultze, Joachim L.

“…Immune tolerance is a central mechanism counteracting tumor-specific immunity and preventing effective anticancer immunotherapy. Induction of tolerance…”
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Drinking Ethanol Has Few Acute Effects on CYP2C9, CYP2C19, NAT2, and P‐Glycoprotein Activities but Somewhat Inhibits CYP1A2, CYP2D6, and Intestinal CYP3A: So What? by Gazzaz, Malaz, Kinzig, Martina, Schaeffeler, Elke, Jübner, Martin, Hsin, Chih‐hsuan, Li, Xia, Taubert, Max, Trueck, Christina, Iltgen‐Breburda, Juliane, Kraus, Daria, Queckenberg, Christian, Stoffel, Marc, Schwab, Matthias, Sörgel, Fritz, Fuhr, Uwe

“…We quantified the effect of acute ethanol exposure (initial blood concentrations 0.7 g/L) on major drug metabolizing enzymes and p‐glycoprotein. Sixteen…”
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Mixed chimerism of the resident macrophage population after allogeneic bone marrow transplantation for chronic myeloid leukemia by WICKENHAUSER, Claudia, THIELE, Juergen, PEREZ, Fernando, VARUS, Eva, STOFFEL, Marc Sebastian, KVASNICKA, Hans Michael, BEELEN, Dietrich Wilhelm, SCHAEFER, Ullrich Wilhelm

“…Bone marrow macrophages have been recognized to play a crucial role in the functional network that constitutes the microenvironment. In chronic myelogenous…”
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MIXED CHIMERISM OF THE RESIDENT MACROPHAGE POPULATION AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION FOR CHRONIC MYELOID LEUKEMIA1 by Wickenhauser, Claudia, Thiele, Juergen, Pérez, Fernando, Varus, Eva, Stoffel, Marc Sebastian, Kvasnicka, Hans Michael, Beelen, Dietrich Wilhelm, Schaefer, Ullrich Wilhelm

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