Search Results - "Stoeken, G."

Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications by Kissel, T, Reijm, S, Slot, L M, Cavallari, M, Wortel, C M, Vergroesen, R D, Stoeken-Rijsbergen, G, Kwekkeboom, J C, Kampstra, Asb, Levarht, Ewn, Drijfhout, J W, Bang, H, Bonger, K M, Janssen, Gmc, van Veelen, P A, Huizinga, Twj, Scherer, H U, Reth, M, Toes, Rem

“…Autoantibodies against antigens carrying distinct post-translational modifications (PTMs), such as citrulline, homocitrulline or acetyllysine, are hallmarks of…”
Get more information

Genetic variants in IL15 associate with progression of joint destruction in rheumatoid arthritis: a multicohort study by Knevel, R, Krabben, A, Brouwer, E, Posthumus, M D, Wilson, A G, Lindqvist, E, Saxne, T, de Rooy, D, Daha, N, van der Linden, M P M, Stoeken, G, van Toorn, L, Koeleman, B, Tsonaka, R, Zhernakoza, A, Houwing-Duistermaat, J J, Toes, R, Huizinga, T W J, van der Helm-van Mil, A

“…Interleukin (IL)-15 levels are increased in serum, synovium and bone marrow of patients with rheumatoid arthritis (RA). IL-15 influences both the innate and…”
Get more information

Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis by Trouw, L. A., Daha, N., Kurreeman, F. A. S., Böhringer, S., Goulielmos, G. N., Westra, H. J., Zhernakova, A., Franke, L., Stahl, E. A., Levarht, E. W. N., Stoeken‐Rijsbergen, G., Verduijn, W., Roos, A., Li, Y., Houwing‐Duistermaat, J. J., Huizinga, T. W. J., Toes, R. E. M.

“…Summary Rodent models for arthritis implicate a role for complement in disease development and progression. In humans, complement deposition has been observed…”
Get full text

Diagnostic value of anti-MCV antibodies in differentiating early inflammatory arthritis by Damjanovska, L, Thabet, M M, Levarth, E W N, Stoeken-Rijsbergen, G, van der Voort, E I, Toes, R E M, Huizinga, T W J, van der Helm-van Mil, A H M

“…To evaluates the diagnostic performance of the anti-CCP2, anti-CCP3 and anti-mutated citrullinated vimentin (anti-MCV) tests in differentiating rheumatoid…”
Get more information

Brief Report: Association of Genetic Variants in the IL4 and IL4R Genes With the Severity of Joint Damage in Rheumatoid Arthritis: A Study in Seven Cohorts by Krabben, A., Wilson, A. G., Rooy, D. P. C., Zhernakova, A., Brouwer, E., Lindqvist, E., Saxne, T., Stoeken, G., Nies, J. A. B., Knevel, R., Huizinga, T. W. J., Toes, R., Gregersen, P. K., Helm‐van Mil, A. H. M.

“…Objective The progression of joint destruction in rheumatoid arthritis (RA) is determined by genetic factors. Changes in IL4 and IL4R genes have been…”
Get full text

The major risk alleles of age‐related macular degeneration (AMD) in CFH do not play a major role in rheumatoid arthritis (RA) by Trouw, L. A., Böhringer, S., Daha, N. A., Stahl, E. A., Raychaudhuri, S., Kurreeman, F. A., Stoeken‐Rijsbergen, G., Houwing‐Duistermaat, J. J., Huizinga, T. W., Toes, R. E.

“…Summary Because activation of the alternative pathway (AP) of the complement system is an important aspect of both age‐related macular degeneration (AMD) and…”
Get full text

A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides by Bossini-Castillo, L, de Kovel, C, Kallberg, H, van 't Slot, R, Italiaander, A, Coenen, M, Tak, P P, Posthumus, M D, Wijmenga, C, Huizinga, T, van der Helm-van Mil, A H M, Stoeken-Rijsbergen, G, Rodriguez-Rodriguez, Luis, Balsa, Alejandro, González-Álvaro, Isidoro, González-Gay, Miguel Ángel, Gómez-Vaquero, Carmen, Franke, B, Vermeulen, S, van der Horst-Bruinsma, Ie, Dijkmans, B A C, Wolbink, G J, Ophoff, R A, Maehlen, M T, van Riel, P, Merriman, M, Klareskog, L, Lie, B A, Merriman, T, Crusius, J B A, Brouwer, E, Martin, J, de Vries, N, Toes, R, Padyukov, L, Koeleman, B P C

“…Rheumatoid arthritis (RA) patients can be classified based on presence or absence of anticitrullinated peptide antibodies (ACPA) in their serum. This…”
Get more information

The RAGE G82S polymorphism is not associated with rheumatoid arthritis independently of HLA-DRB10401 by Steenvoorden, M. M. C., van der Helm-van Mil, A. H. M., Stoeken, G., Bank, R. A., DeVries, R. R. P., Huizinga, T. W. J., DeGroot, J., Toes, R. E. M.

Get full text

Genetic variants of C1q are a risk for rheumatoid arthritis by Daha, N.A., Kurreeman, F.A.S., Böhringer, S., Stoeken-Rijsbergen, G., Houwing-Duistermaat, J.J., Huizinga, T.W., Toes, R.E.M., Trouw, L.A.

Get full text

Association of genetic variants in the IL4 and IL4R genes with the severity of joint damage in rheumatoid arthritis: a study in seven cohorts by Krabben, A, Wilson, A G, de Rooy, D P C, Zhernakova, A, Brouwer, E, Lindqvist, E, Saxne, T, Stoeken, G, van Nies, J A B, Knevel, R, Huizinga, T W J, Toes, R, Gregersen, P K, van der Helm-van Mil, A H M

“…The progression of joint destruction in rheumatoid arthritis (RA) is determined by genetic factors. Changes in IL4 and IL4R genes have been associated with RA…”
Get full text

Association of the autoimmunity locus 4q27 with juvenile idiopathic arthritis by Albers, H. M., Kurreeman, F. A. S., Stoeken‐Rijsbergen, G., Brinkman, D. M. C., Kamphuis, S. S. M., van Rossum, M. A. J., Girschick, H. J., Wouters, C., Saurenmann, R. K., Hoppenreijs, E., Slagboom, P., Houwing‐Duistermaat, J. J., Verduijn, W., Huizinga, T. W. J., ten Cate, R., Toes, R. E. M., Schilham, M. W.

“…Objective Juvenile idiopathic arthritis (JIA) is characterized by chronic arthritis and an autoimmune etiology. In several autoimmune diseases, including…”
Get full text

Novel genetic association of the VTCN1 region with rheumatoid arthritis by Daha, Nina A, Lie, Benedicte A, Trouw, L A, Stoeken, Gerrie, Schonkeren, Joris J M, Ding, Bo, Kvien, Tore K, Schilham, Marco W, Padyukov, Leonid, Huizinga, T W J, Toes, Rene

“…Based upon findings in juvenile idiopathic arthritis, the genetic contribution of the VTCN1 region to rheumatoid arthritis (RA) susceptibility and…”
Get more information

Association of the –2849 interleukin‐10 promoter polymorphism with autoantibody production and joint destruction in rheumatoid arthritis by Lard, L. R., van Gaalen, F. A., Schonkeren, J. J. M., Pieterman, E. J., Stoeken, G., Vos, K., Nelissen, R. G. H. H., Westendorp, R. G. J., Hoeben, R. C., Breedveld, F. C., Toes, R. E. M., Huizinga, T. W. J.

“…Objective To analyze the –2849 A/G interleukin‐10 (IL‐10) promoter polymorphism, which is associated with high (AG/GG) and low (AA) IL‐10 production, in a…”
Get full text

Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation by Kissel, Theresa, Ge, Changrong, Hafkenscheid, Lise, Kwekkeboom, Joanneke C, Slot, Linda M, Cavallari, Marco, He, Yibo, van Schie, Karin A, Vergroesen, Rochelle D, Kampstra, Arieke S B, Reijm, Sanne, Stoeken-Rijsbergen, Gerrie, Koeleman, Carolien, Voortman, Lennard M, Heitman, Laura H, Xu, Bingze, Pruijn, Ger J M, Wuhrer, Manfred, Rispens, Theo, Huizinga, Tom W J, Scherer, Hans Ulrich, Reth, Michael, Holmdahl, Rikard, Toes, Rene E M

“…The hallmark autoantibodies in rheumatoid arthritis are characterized by variable domain glycans (VDGs). Their abundant occurrence results from the selective…”
Get full text

A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis by Kurreeman, Fina A S, Padyukov, Leonid, Marques, Rute B, Schrodi, Steven J, Seddighzadeh, Maria, Stoeken-Rijsbergen, Gerrie, van der Helm-van Mil, Annette H M, Allaart, Cornelia F, Verduyn, Willem, Houwing-Duistermaat, Jeanine, Alfredsson, Lars, Begovich, Ann B, Klareskog, Lars, Huizinga, Tom W J, Toes, Rene E M

“…Rheumatoid arthritis (RA) is a chronic autoimmune disorder affecting approximately 1% of the population. The disease results from the interplay between an…”
Get full text

A polymorphism in the IL-10 promoter affects autoantibody production and subsequent joint destruction in rheumatoid arthritis by van Gaalen, FA, Lard, L, Schonkeren, J, Pieterman, E, Stoeken, G, Vos, K, Nelissen, R, Westendorp, R, Hoeben, R, Breedveld, FC, Toes, R, Huizinga, TWJ

Get full text

The role of interleukin 10 promoter polymorphisms in the susceptibility of distal interphalangeal osteoarthritis by Riyazi, Naghmeh, Kurreeman, Fina A S, Huizinga, Tom W J, Dekker, Friedo W, Stoeken-Rijsbergen, Gerrie, Kloppenburg, Margreet

“…OBJECTIVE: The interleukin (IL)-10 single nucleotide promoter polymorphism (SNP) -2849A is associated with decreased IL-10 production as measured by…”
Get full text

A candidate gene approach identifies the TRAF1 / C5 region as a risk factor for rheumatoid arthritis (vol 4, artn no e278, 2007) by Kurreeman, FAS, Padyukov, L, Marques, RB, Schrodi, SJ, Seddighzadeh, M, Stoeken-Rijsbergen, G, van der Helm-van Mil, AHM, Allaart, CF, Verduyn, W, Houwing-Duistermaat, J, Alfredsson, L, Begovich, B, Klareskog, L, Huizinga, TWJ, Toes, REM

Get full text

Contribution of Fcgamma receptor IIIA gene 158V/F polymorphism and copy number variation to the risk of ACPA-positive rheumatoid arthritis by Thabet, M M, Huizinga, T W J, Marques, R B, Stoeken-Rijsbergen, G, Bakker, A M, Kurreeman, F A, White, S J, Toes, R E M, van der Helm-van Mil, A H M

“…Fcgamma receptors (FcgammaRs) are potent immune modulators. FcgammaR genes encompass a complex region, polymorphic by both single nucleotide polymorphisms…”
Get more information