Search Results - "Stoclet, Jean Claude"
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Glycyrrhetinic Acid Reverses the Lipopolysaccharide-Induced Hypocontractility to Noradrenaline in Rat Aorta: Implications to Septic Shock
Published in Journal of Pharmacological Sciences (2014)“…Septic shock and associated vascular hyporeactivity to vasoconstrictor agonists remain a major problem of critical care medicine. Here we report that…”
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A human tissue‐engineered vascular media: a new model for pharmacological studies of contractile responses
Published in The FASEB journal (01-02-2001)“…ABSTRACT Our method for producing tissue‐engineered blood vessels based exclusively on the use of human cells, i.e., without artificial scaffolding, has…”
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3
Y27632, a Rho-activated kinase inhibitor, normalizes dysregulation in alpha1-adrenergic receptor-induced contraction of Lyon hypertensive rat artery smooth muscle
Published in Fundamental & clinical pharmacology (01-04-2009)“…RhoA‐activated kinase (ROK) is involved in the disorders of smooth muscle contraction found in hypertension model animals and patients. We examined whether the…”
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Red Wine Polyphenolic Compounds Inhibit Vascular Endothelial Growth Factor Expression in Vascular Smooth Muscle Cells by Preventing the Activation of the p38 Mitogen-Activated Protein Kinase Pathway
Published in Arteriosclerosis, thrombosis, and vascular biology (01-06-2003)“…OBJECTIVE—Moderate consumption of red wine has a beneficial effect on the cardiovascular system. This study examines whether red wine polyphenolic compounds…”
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Vascular bed heterogeneity in age‐related endothelial dysfunction with respect to NO and eicosanoids
Published in British journal of pharmacology (01-09-2000)“…Endothelial dysfunction has been described with ageing but the mechanisms responsible have not been clearly elucidated and might be different from one vessel…”
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Nitric Oxide Transport and Storage in the Cardiovascular System
Published in Annals of the New York Academy of Sciences (01-05-2002)“…: Despite short halflife in biological fluids, nitric oxide (NO) can produce remote or long lasting effect in the cardiovascular system. Long distance…”
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S-nitrosating nitric oxide donors induce long-lasting inhibition of contraction in isolated arteries
Published in The Journal of pharmacology and experimental therapeutics (01-10-2003)“…The ability of various nitric oxide (NO) donors to induce long-lasting inhibition of contraction in isolated arteries was compared. All the studied compounds…”
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Vascular protection by dietary polyphenols
Published in European journal of pharmacology (01-10-2004)“…Consumption of polyphenol-rich foods, such as fruits and vegetables, and beverages derived from plants, such as cocoa, red wine and tea, may represent a…”
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Role of S-nitrosation of cysteine residues in long-lasting inhibitory effect of nitric oxide on arterial tone
Published in Molecular pharmacology (01-05-2003)“…S-Nitrosation of cysteine residues plays an important role in nitric oxide (NO) signaling and transport. The aim of the present study was to investigate the…”
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Adventitia-derived nitric oxide in rat aortas exposed to endotoxin: cell origin and functional consequences
Published in American journal of physiology. Heart and circulatory physiology (01-12-2000)“…The role of adventitial cells in bacterial lipopolysaccharide (LPS)-induced vascular nitric oxide (NO) overproduction has been largely ignored. In rat aortas…”
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The inducible nitric oxide synthase in vascular and cardiac tissue
Published in European Journal of Pharmacology (30-06-1999)“…Expression of the inducible form of nitric oxide synthase (iNOS) has been reported in a variety of cardiovascular diseases. The resulting high output nitric…”
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Book Review Conference Proceeding Journal Article -
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Role of adventitial nitric oxide in vascular hyporeactivity induced by lipopolysaccharide in rat aorta
Published in British journal of pharmacology (01-06-1998)“…This study was designed to elucidate the role of the adventitia in NO‐mediated vascular effects of lipopolysaccharide (LPS). After incubation of rat aorta with…”
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13
Resistance to endotoxic shock as a consequence of defective NF-κB activation in poly (ADP-ribose) polymerase-1 deficient mice
Published in The EMBO journal (16-08-1999)“…Poly (ADP‐ribose) polymerase‐1 is a nuclear DNA‐binding protein that participates in the DNA base excision repair pathway in response to genotoxic stress in…”
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14
Endothelium‐dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors
Published in British journal of pharmacology (01-10-1991)“…1 The effects of selective inhibitors of adenosine 3′: 5′‐cyclic monophosphate (cyclic AMP) and guanosine 3′: 5′‐cyclic monophosphate (cyclic GMP)…”
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Red wine polyphenols cause endothelium-dependent EDHF-mediated relaxations in porcine coronary arteries via a redox-sensitive mechanism
Published in Biochemical and biophysical research communications (17-10-2003)“…Moderate consumption of wine is associated with cardiovascular protection most likely by increasing the endothelial formation of nitric oxide (NO). The present…”
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Nitric oxide‐related cyclic GMP‐independent relaxing effect of N‐acetylcysteine in lipopolysaccharide‐treated rat aorta
Published in British journal of pharmacology (01-03-1998)“…1 We have recently demonstrated the formation of protein‐bound dinitrosyl‐iron complexes (DNIC) in rat aortic rings exposed to lipopolysaccharide (LPS) and…”
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Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta
Published in The Journal of nutrition (01-12-1998)“…This study investigated the possible active principles which support the endothelial nitric oxide-dependent relaxation produced by red wine and other plant…”
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Dependence of endotoxin‐induced vascular hyporeactivity on extracellular l‐arginine
Published in British journal of pharmacology (01-01-1993)“…1 The dependence on extracellular l‐arginine of vascular hyporeactivity induced by bacterial lipopolysaccharide (LPS) was studied in vivo in rats infused with…”
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Nitric oxide production and endothelium‐dependent vasorelaxation induced by wine polyphenols in rat aorta
Published in British journal of pharmacology (01-03-1997)“…The aim of this work was to investigate the mechanism of vasorelaxation induced by red wine polyphenolic compounds (RWPC) and two defined polyphenols contained…”
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Hyporeactivity of mesenteric vascular bed in endotoxin-treated rats
Published in European journal of pharmacology (08-08-1996)“…Vascular reactivity and activation of the nitric oxide (NO) pathway were investigated in perfused mesenteric vascular bed removed from rats 5 h after i.p…”
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