Search Results - "Stockmann, Adam"

Intestinal Npt2b Plays a Major Role in Phosphate Absorption and Homeostasis by SABBAGH, Yves, O'BRIEN, Stephen P, WENPING SONG, BOULANGER, Joseph H, STOCKMANN, Adam, ARBEENY, Cynthia, SCHIAVI, Susan C

“…Intestinal phosphate absorption occurs through both a paracellular mechanism involving tight junctions and an active transcellular mechanism involving the type…”
Get full text

Engineered red blood cells (activating antigen carriers) drive potent T cell responses and tumor regression in mice by Blagovic, Katarina, Smith, Carolyne K., Ramakrishnan, Amritha, Moore, Lindsay, Soto, David R., Thompson, Zachary, Stockmann, Adam P., Kruszelnicki, Sonia, Thakkar, Akshi, Murray, Jason, Torres, Sebastian, Wondimagegnhu, Bersabel, Yi, Roslyn, Dadgar, Maisam, Paracha, Abdul M., Page, Claire, Clear, Louise, Chaudhry, Omer A., Myint, Melissa, Bridgen, Devin T., Gilbert, Jonathan B., Seidl, Katherine J., Sharei, Armon, Loughhead, Scott, Bernstein, Howard, Yarar, Defne

“…Activation of T cell responses is essential for effective tumor clearance; however, inducing targeted, potent antigen presentation to stimulate T cell…”
Get full text

170 Microfluidics cell squeezing enables potent cellular vaccines in murine models through direct cytosolic loading and direct CD8 T cell priming by Ozay, Emrah, Booty, Matthew, Blagovic, Katarina, Soto, David, Pryor, Olivia, Stockmann, Adam, Subramanya, Disha, Volk, Kelly, Sharei, Armon, Bernstein, Howard, Yarar, Defne, Seidl, Katherine, Loughhead, Scott

“…BackgroundThe presentation of sufficient antigen on major histocompatibility complex class I (MHC-I) is essential to prime CD8+ T cells.MethodsTo achieve…”
Get full text

Abstract 3209: CRLX101, an investigational nanoparticle-drug conjugate of camptothecin, demonstrates synergy with immunotherapy agents in preclinical models by Lazarus, Douglas, Peters, Christian, Stockmann, Adam, Eliasof, Scott, Jayaraman, Lata

“…Abstract CRLX101, an investigational nanoparticle-drug conjugate (NDC) containing the payload camptothecin, is currently being clinically evaluated in multiple…”
Get full text

Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8 + T Cell Responses with Antitumor Activity by Booty, Matthew G, Hlavaty, Kelan A, Stockmann, Adam, Ozay, Emrah Ilker, Smith, Carolyne, Tian, Lina, How, Edylle, Subramanya, Disha, Venkitaraman, Anita, Yee, Christian, Pryor, Olivia, Volk, Kelly, Blagovic, Katarina, Vicente-Suarez, Ildefonso, Yarar, Defne, Myint, Melissa, Merino, Amy, Chow, Jonathan, Abdeljawad, Tarek, An, Harry, Liu, Sophia, Mao, Shirley, Heimann, Megan, Talarico, LeeAnn, Jacques, Miye K, Chong, Eritza, Pomerance, Lucas, Gonzalez, John T, von Andrian, Ulrich H, Jensen, Klavs F, Langer, Robert, Knoetgen, Hendrik, Trumpfheller, Christine, Umaña, Pablo, Bernstein, Howard, Sharei, Armon, Loughhead, Scott M

“…CD8 T cell responses are the foundation of the recent clinical success of immunotherapy in oncologic indications. Although checkpoint inhibitors have enhanced…”
Get full text

Abstract 1345: Tumor selective localization of CRLX101, an investigational nanoparticle-drug conjugate of camptothecin by Peters, Christian G., Lazarus, Douglas, Brown, Donna, Zhang, Ningning, Stockmann, Adam P., Case, Roy, Rohde, Ellen, Eliasof, Scott, Jayaraman, Lata

“…Abstract CRLX101, an investigational nanoparticle-drug conjugate (NDC) containing the payload camptothecin, is currently being clinically evaluated in multiple…”
Get full text

Teriflunomide Does Not Significantly Affect Primary and Memory Antibody Responses to a Viral Antigen in Mice (P1.215) by Edling, Andrea, Woodworth, Lisa, Stockmann, Adam, Touzjian, Tracy, Fricker, Simon, Roberts, Bruce, Kaplan, Johanne

“…Abstract only…”
Get full text

Abstract PR10: Significant improvements in therapeutic index for conjugated payloads using a nanoparticle-drug conjugate (NDC) platform to provide sustained drug release and potentially improved anticancer effects by Metcalf, Chester, Poll, Derek van der, Zhao, Liang, Halo, Tiffany, Lazarus, Doug, Stockmann, Adam, Peters, Christian, Brown, Donna, Case, Roy, Rohde, Ellen, Jayaraman, Lata, Wang, Hongwei, Crowell, Tiffany, Senderowicz, Adrian, Eliasof, Scott

“…Abstract Cerulean Pharma Inc.'s Dynamic Tumor Targeting™ Platform creates nanoparticle-drug conjugates (NDCs) designed to significantly mitigate a payload's…”
Get full text

141 PBMC-based cancer vaccines generated with microfluidics squeezing demonstrate synergistic and durable tumor reduction in combination with PD1 checkpoint and FAP targeted IL-2 variants by Booty, Matthew, Stockmann, Adam, Pryor, Olivia, Myint, Melissa, Trumpfheller, Christine, Nicolini, Valeria, Klein, Christian, Codarri, Laura, Umana, Pablo, Armon Sharei, Bernstein, Howard, Seidl, Katherine, Loughhead, Scott

“…BackgroundWe engineered unfractionated peripheral blood mononuclear cells (PBMCs) to function as antigen presenting cells (APCs) that generate potent CD8+ T…”
Get full text