Search Results - "Stocking, Kim L"

An Essential Role for Ectodomain Shedding in Mammalian Development by Peschon, Jacques J., Slack, Jennifer L., Reddy, Pranitha, Stocking, Kim L., Sunnarborg, Susan W., Lee, David C., Russell, William E., Castner, Beverly J., Johnson, Richard S., Fitzner, Jeffrey N., Boyce, Rogely W., Nelson, Nicole, Kozlosky, Carl J., Wolfson, Martin F., Rauch, Charles T., Cerretti, Douglas Pat, Paxton, Raymond J., March, Carl J., Black, Roy A.

“…The ectodomains of numerous proteins are released from cells by proteolysis to yield soluble intercellular regulators. The responsible protease, tumor necrosis…”
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TNF Receptor-Deficient Mice Reveal Divergent Roles for p55 and p75 in Several Models of Inflammation by Peschon, Jacques J, Torrance, Dauphine S, Stocking, Kim L, Glaccum, Moira B, Otten, Carol, Willis, Cynthia R, Charrier, Keith, Morrissey, Philip J, Ware, Carol B, Mohler, Kendall M

“…The pleiotropic activities of the potent proinflammatory cytokine TNF are mediated by two structurally related, but functionally distinct, receptors, p55 and…”
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Elucidation of the thromboregulatory role of CD39/ectoapyrase in the ischemic brain by Pinsky, David J, Broekman, M Johan, Peschon, Jacques J, Stocking, Kim L, Fujita, Tomoyuki, Ramasamy, Ravichandran, Connolly, Jr, E Sander, Huang, Judy, Kiss, Szilard, Zhang, Yuan, Choudhri, Tanvir F, McTaggart, Ryan A, Liao, Hui, Drosopoulos, Joan H F, Price, Virginia L, Marcus, Aaron J, Maliszewski, Charles R

“…Endothelial CD39 metabolizes ADP released from activated platelets. Recombinant soluble human CD39 (solCD39) potently inhibited ex vivo platelet aggregation in…”
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Comparison of Submental Blood Collection with the Retroorbital and Submandibular Methods in Mice (Mus musculus) by Regan, Rainy D, Fenyk-Melody, Judy E, Tran, Sam M, Chen, Guang, Stocking, Kim L

“…Nonterminal blood sample collection of sufficient volume and quality for research is complicated in mice due to their small size and anatomy. Large (>100 μL)…”
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Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense by Ye, P, Rodriguez, F H, Kanaly, S, Stocking, K L, Schurr, J, Schwarzenberger, P, Oliver, P, Huang, W, Zhang, P, Zhang, J, Shellito, J E, Bagby, G J, Nelson, S, Charrier, K, Peschon, J J, Kolls, J K

“…Bacterial pneumonia is an increasing complication of HIV infection and inversely correlates with the CD4(+) lymphocyte count. Interleukin (IL)-17 is a cytokine…”
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Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells by McKenna, Hilary J., Stocking, Kim L., Miller, Robert E., Brasel, Kenneth, De Smedt, Thibaut, Maraskovsky, Eugene, Maliszewski, Charles R., Lynch, David H., Smith, Jeffrey, Pulendran, Bali, Roux, Eileen R., Teepe, Mark, Lyman, Stewart D., Peschon, Jacques J.

“…The ligand for the receptor tyrosine kinase fms-like tyrosine kinase 3 (flt3), also referred to as fetal liver kinase-2 (flk-2), has an important role in…”
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A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells by Black, Roy A, Rauch, Charles T, Kozlosky, Carl J, Peschon, Jacques J, Slack, Jennifer L, Wolfson, Martin F, Castner, Beverly J, Stocking, Kim L, Reddy, Pranitha, Srinivasan, Subhashini, Nelson, Nicole, Boiani, Norman, Schooley, Kenneth A, Gerhart, Mary, Davis, Raymond, Fitzner, Jeffrey N, Johnson, Richard S, Paxton, Raymond J, March, Carl J, Cerretti, Douglas Pat

“…Mammalian cells proteolytically release (shed) the extracellular domains of many cell-surface proteins. Modification of the cell surface in this way can alter…”
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Analysis of 4-1BB Ligand (4-1BBL)-Deficient Mice and of Mice Lacking Both 4-1BBL and CD28 Reveals a Role for 4-1BBL in Skin Allograft Rejection and in the Cytotoxic T Cell Response to Influenza Virus by DeBenedette, Mark A, Wen, Tao, Bachmann, Martin F, Ohashi, Pamela S, Barber, Brian H, Stocking, Kim L, Peschon, Jacques J, Watts, Tania H

“…4-1BB ligand (4-1BBL) is a member of the TNF family expressed on activated APC. 4-1BBL binds to 4-1BB (CD137) on activated CD4 and CD8 T cells and in…”
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Use of Low-Molecular-Weight Heparin to Decrease Mortality in Mice after Intracardiac Injection of Tumor Cells by Stocking, Kim L, Jones, Jon C, Everds, Nancy E, Buetow, Bernard S, Roudier, Martine P, Miller, Robert E

“…Intracardiac injection of human tumor cells into anesthetized nude mice is an established model of bone metastasis. However, intracardiac injection of some…”
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Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells by McKenna, Hilary J., Stocking, Kim L., Miller, Robert E., Brasel, Kenneth, De Smedt, Thibaut, Maraskovsky, Eugene, Maliszewski, Charles R., Lynch, David H., Smith, Jeffrey, Pulendran, Bali, Roux, Eileen R., Teepe, Mark, Lyman, Stewart D., Peschon, Jacques J.

“…The ligand for the receptor tyrosine kinase fms-like tyrosine kinase 3 (flt3), also referred to as fetal liver kinase-2 (flk-2), has an important role in…”
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Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor by Buxbaum, Joseph D., Liu, Kang-Nian, Luo, Yuxia, Slack, Jennifer L., Stocking, Kim L., Peschon, Jacques J., Johnson, Richard S., Castner, Beverly J., Cerretti, Douglas Pat, Black, Roy A.

“…The amyloid protein, Aβ, which accumulates in the brains of Alzheimer patients, is derived by proteolysis of the amyloid protein precursor (APP). APP can…”
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Phenotypic and functional characterization of mice that lack the type I receptor for IL-1 by Glaccum, MB, Stocking, KL, Charrier, K, Smith, JL, Willis, CR, Maliszewski, C, Livingston, DJ, Peschon, JJ, Morrissey, PJ

“…IL-1 alpha and IL-1 beta bind to receptors termed the type I and type II IL-1 receptors. The type I IL-1 receptor is responsible for specific signaling, while…”
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Elucidation of the thromboregulatory role of CD39/ectoapyrase in the ischemic brain by Pinsky, David J., Broekman, M. Johan, Peschon, Jacques J., Stocking, Kim L., Fujita, Tomoyuki, Ramasamy, Ravichandran, Connolly, E. Sander, Huang, Judy, Kiss, Szilard, Zhang, Yuan, Choudhri, Tanvir F., McTaggart, Ryan A., Liao, Hui, Drosopoulos, Joan H.F., Price, Virginia L., Marcus, Aaron J., Maliszewski, Charles R.

“…Endothelial CD39 metabolizes ADP released from activated platelets. Recombinant soluble human CD39 (solCD39) potently inhibited ex vivo platelet aggregation in…”
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Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor by Joseph D. Buxbaum, Kang-Nian Liu, Yuxia Luo, Jennifer L. Slack, Kim L. Stocking, Jacques J. Peschon, Richard S. Johnson, Beverly J. Castner, Douglas Pat Cerretti, Roy A. Black

“…The amyloid protein, Aβ, which accumulates in the brains of Alzheimer patients, is derived by proteolysis of the amyloid protein precursor (APP). APP can…”
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