Search Results - "Stockhausen, M. T."

Replication stress and oxidative damage contribute to aberrant constitutive activation of DNA damage signalling in human gliomas by Bartkova, J, Hamerlik, P, Stockhausen, M-T, Ehrmann, J, Hlobilkova, A, Laursen, H, Kalita, O, Kolar, Z, Poulsen, H S, Broholm, H, Lukas, J, Bartek, J

“…Malignant gliomas, the deadliest of brain neoplasms, show rampant genetic instability and resistance to genotoxic therapies, implicating potentially aberrant…”
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Effects of the histone deacetylase inhibitor valproic acid on Notch signalling in human neuroblastoma cells by STOCKHAUSEN, M.-T, SJÖLUND, J, ATANETOPOULOS, C, AXELSON, H

“…Neuroblastoma (NB), a sympathetically derived childhood tumour, shows characteristics of neuronal precursor cells, suggesting a halted differentiation process…”
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The functional role of Notch signaling in human gliomas by Stockhausen, Marie-Thérése, Kristoffersen, Karina, Poulsen, Hans Skovgaard

“…Gliomas are among the most devastating adult tumors for which there is currently no cure. The tumors are derived from brain glial tissue and comprise several…”
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P17.91 CLINICAL VARIABLES SERVE AS PREDICTIVE FACTORS IN A MODEL FOR CLINICAL RESPONSE TO BEVACIZUMAB IN RECURRENT GLIOBLASTOMA MULTIFORME: AN OBSERVATIONAL STUDY OF A COHORT OF CONSECUTIVE NON-SELECTED PATIENTS FROM A SINGLE INSTITUTION by Urup, T., Grunnet, K., Christensen, I. J., Michaelsen, S. R., Broholm, H., Stockhausen, M. T., Lassen, U., Poulsen, H. S.

“…Bevacizumab (BEV), a humanized monoclonal antibody against vascular endothelial growth factor A, has demonstrated activity in patients with recurrent…”
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The Notch pathway in cancer: Differentiation gone awry by Sjölund, Jonas, Manetopoulos, Christina, Stockhausen, Marie-Thérése, Axelson, Håkan

“…The Notch signalling cascade influences several key aspects of normal development by regulating differentiation, proliferation and apoptosis. Its association…”
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Ubiquilin-1 is a novel HASH-1-complexing protein that regulates levels of neuronal bHLH transcription factors in human neuroblastoma cells by Persson, Paula, Stockhausen, Marie-Thérése, Påhlman, Sven, Axelson, Håkan

“…The basic helix-loop-helix (bHLH) transcription factor mammalian achaete-scute homologue-1 (MASH-1 in mouse and HASH-1 in humans) is expressed in specific…”
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TUMOR MODELS (IN VIVO/IN VITRO) by Brognaro, E., Chang, S., Cha, J., Choi, K., Choi, C., DePetro, J., Binding, C., Blough, M., Kelly, J., Lawn, S., Chan, J., Weiss, S., Cairncross, G., Eisenbeis, A., Goldbrunner, R., Timmer, M., Gabrusiewicz, K., Cortes-Santiago, N., Fan, X., Hossain, M. B., Kaminska, B., Heimberger, A., Rao, G., Yung, W. K. A., Marini, F., Fueyo, J., Gomez-Manzano, C., Halle, B., Marcusson, E., Aaberg-Jessen, C., Jensen, S. S., Meyer, M., Schulz, M. K., Andersen, C., Bjarne, Kristensen, W., Hashizume, R., Ihara, Y., Ozawa, T., Parsa, A., Clarke, J., Butowski, N., Prados, M., Perry, A., McDermott, M., James, D., Jensen, R., Gillespie, D., Martens, T., Zamykal, M., Westphal, M., Lamszus, K., Monsalves, E., Jalali, S., Tateno, T., Ezzat, S., Zadeh, G., Nedergaard, M. K., Kristoffersen, K., Poulsen, H. S., Stockhausen, M.-T., Lassen, U., Kjaer, A., Ohka, F., Natsume, A., Zong, H., Liu, C., Hatanaka, A., Katsushima, K., Shinjo, K., Wakabayashi, T., Kondo, Y., Picotte, K., Li, L., Westerhuis, B., Zhao, H., Plotkin, S., James, M., Kalamarides, M., Zhao, W.-n., Kim, J., Stemmer-Rachamimov, A., Haggarty, S., Gusella, J., Ramesh, V., Nunes, F., Doucette, T., Yang, Y., Fuller, G., Rao, A., Schmidt, N. O., Humke, N., Meissner, H., Mueller, F.-J., Schnell, O., Jaehnert, I., Albrecht, V., Fu, P., Tonn, J.-C., Schichor, C.

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Regulation of the Notch target gene Hes-1 by TGFα induced Ras/MAPK signaling in human neuroblastoma cells by Stockhausen, Marie-Thérése, Sjölund, Jonas, Axelson, Håkan

“…Ras and Notch signaling have recently been shown to cooperate in the maintenance of neoplastic transformation. Here, we show that TGFα, a known activator of…”
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Stem Cells by He, H., Emmett, M. R., Marshall, A. G., Ji, Y., Conrad, C. A., Priebe, W., Colman, H., Lang, F. F., Madden, T. L., Kristoffersen, K., Stockhausen, M.-T., Poulsen, H. S., Binder, Z. A., Orr, B., Lim, M., Weingart, J. D., Brem, H., Olivi, A., Riggins, G. J., Gallia, G. L., Litofsky, N. S., Miller, D. C., Rath, P., Anthony, D. C., Feng, Q., Franklin, C., Pei, L., Free, A., Kirk, M. D., Shi, H., Timmer, M., Theiss, H., Juerchott, K., Ries, C., Paron, I., Franz, W., Selbig, J., Guo, K., Tonn, J. C., Schichor, C., Zhou, Y.-H., Hu, Y., Pioli, P. D., Rajneesh, K., Limoli, C. L., Yu, L., Hess, K. R., Linskey, M. E., Faber, F., Jaeger, D., Thorsteinsdottir, J., Albrecht, V., Tonn, J.-C., Price, R., Song, J., Zimmerman, P., Duale, H., Rivera, A., Kaur, B., Parada, L., Cook, C., Chiocca, E. A., Kwon, C.-H., Munoz, D. M., Guha, A., Estrada-Bernal, A., Van Brocklyn, J. R., Gu, C., Mahasenan, K. V., Joshi, K., Gupta, S., Mattson, A., Li, C., Nakano, I., Chi, A. S., Rheinbay, E., Wakimoto, H., Gillespie, S., Kasif, S., Rabkin, S. D., Martuza, R. L., Bernstein, B. E., Skirboll, S. L., Wurdak, H., Zhu, S., Romero, A., Lorger, M., Watson, J., Chiang, C.-y., Zhang, J., Natu, V. S., Lairson, L. L., Walker, J. R., Trussell, C. M., Harsh, G. R., Vogel, H., Felding-Habermann, B., Orth, A. P., Miraglia, L. J., Rines, D. R.

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Notch signaling in neuroblastoma by Påhlman, Sven, Stockhausen, Marie-Thérése, Fredlund, Erik, Axelson, Håkan

“…Neuroblastoma is a pediatric tumor that originates from precursor cells of the sympathetic nervous system that have discontinued their normal differentiation…”
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