Search Results - "Stockbauer, Kathryn"

Secreted bacterial phospholipase A2 enzymes: better living through phospholipolysis by Sitkiewicz, Izabela, Stockbauer, Kathryn E, Musser, James M

“…Phospholipases are ubiquitous and diverse enzymes that induce changes in membrane composition, activate the inflammatory cascade and alter cell signaling…”
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Rapidly progressive, fatal, inhalation anthrax-like infection in a human: case report, pathogen genome sequencing, pathology, and coordinated response by Wright, Angela M, Beres, Stephen B, Consamus, Erin N, Long, S Wesley, Flores, Anthony R, Barrios, Roberto, Richter, G Stefan, Oh, So-Young, Garufi, Gabriella, Maier, Hannah, Drews, Ashley L, Stockbauer, Kathryn E, Cernoch, Patricia, Schneewind, Olaf, Olsen, Randall J, Musser, James M

“…Ten years ago a bioterrorism event involving Bacillus anthracis spores captured the nation's interest, stimulated extensive new research on this pathogen, and…”
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Restricted Structural Gene Polymorphism in the Mycobacterium tuberculosis Complex Indicates Evolutionarily Recent Global Dissemination by Sreevatsan, Srinand, Pan, Xi, Stockbauer, Kathryn E., Connell, Nancy D., Kreiswirth, Barry N., Whittam, Thomas S., Musser, James M.

“…One-third of humans are infected with Mycobacterium tuberculosis, the causative agent of tuberculosis. Sequence analysis of two megabases in 26 structural…”
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The emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutol by Telenti, Amalio, Philipp, Wolfgang J, Sreevatsan, Srinand, Bernasconi, Claudia, Stockbauer, Kathryn E, Wieles, Brigitte, Musser, James M, Jacobs, William R

“…Ethambutol (EMB), a frontline antituberculous drug, targets the mycobacterial cell wall, a unique structure among prokaryotes which consists of an outer layer…”
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Identification and characterization of BipA, a Bordetella Bvg‐intermediate phase protein by Stockbauer, Kathryn E., Fuchslocher, Bryna, Miller, Jeff F., Cotter, Peggy A.

“…The Bordetella BvgAS sensory transduction system has traditionally been viewed as controlling a transition between two distinct phenotypic phases: the Bvg+ or…”
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Bordetella type III secretion induces caspase 1‐independent necrosis by Stockbauer, Kathryn E., Foreman‐Wykert, Amy K., Miller, Jeff F.

“…Summary The Bordetella bronchiseptica type III (TIII) secretion system induces cytotoxicity in infected macrophages and epithelial cells. In this report we…”
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Hypervariability Generated by Natural Selection in an Extracellular Complement-Inhibiting Protein of Serotype M1 Strains of Group A Streptococcus by Stockbauer, Kathryn E., Grigsby, Diana, Pan, Xi, Fu, Yun-Xin, Luis M. Perea Mejia, Cravioto, Alejandro, Musser, James M.

“…In many countries, M1 strains of the human pathogenic bacterium group A Streptococcus are the most common serotype recovered from patients with invasive…”
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Secreted bacterial phospholipase A 2 enzymes: better living through phospholipolysis by Sitkiewicz, Izabela, Stockbauer, Kathryn E., Musser, James M.

“…Phospholipases are ubiquitous and diverse enzymes that induce changes in membrane composition, activate the inflammatory cascade and alter cell signaling…”
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A Natural Variant of the Cysteine Protease Virulence Factor of Group A Streptococcus with an Arginine-Glycine-Aspartic Acid (RGD) Motif Preferentially Binds Human Integrins αvβ3and αIIbβ3 by Stockbauer, Kathryn E., Magoun, Loranne, Liu, Mengyao, Burns, Eugene H., Gubba, Siddeswar, Renish, Sarah, Pan, Xi, Bodary, Sarah C., Baker, Elizabeth, Coburn, Jenifer, Leong, John M., Musser, James M.

“…The human pathogenic bacterium group A Streptococcus produces an extracellular cysteine protease [streptococcal pyrogenic exotoxin B (SpeB)] that is a critical…”
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Whole Genome Sequence Analysis of a B. cereus Strain Causing a Fatal Anthrax‐Like Pulmonary Infection by Long, S. Wesley, Wright, Angela M, Beres, Stephen B, Consamus, Erin N, Flores, Anthony R, Barrios, Roberto, Richter, G. Stefan, Oh, So-Young, Garufi, Gabriella, Maier, Hannah, Drews, Ashley L, Stockbauer, Kathryn E, Cernoch, Patricia, Schneewind, Olaf, Olsen, Randall J, Musser, James M

“…Abstract only A 39‐year‐old male presented with a rapidly progressive hemorrhagic anthrax‐like pneumonia. Within 3 days, the overwhelming systemic infection…”
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Ethambutol resistance in Mycobacterium tuberculosis: critical role of embB mutations by SREEVATSAN, S, STOCKBAUER, K. E, PAN, X, KREISWIRTH, B. N, MOGHAZEH, S. L, JACOBS, W. R, TELENTI, A, MUSSER, J. M

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Secreted bacterial phospholipase A sub(2) enzymes: better living through phospholipolysis by Sitkiewicz, I, Stockbauer, KE, Musser, J M

“…Phospholipases are ubiquitous and diverse enzymes that induce changes in membrane composition, activate the inflammatory cascade and alter cell signaling…”
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Characterization of rpsL and rrs mutations in streptomycin-resistant Mycobacterium tuberculosis isolates from diverse geographic localities by SRINAND SREEVATSAN, XI PAN, STOCKBAUER, K. E, WILLIAMS, D. L, KREISWIRTH, B. N, MUSSER, J. M

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Rapidly progressive, fatal, inhalation anthrax-like infection in a human: case report, pathogen genome sequencing, pathology, and coordinated response by Wright, Angela M, Beres, Stephen B, Consamus, Erin N, Long, S. Wesley, Flores, Anthony R, Barrios, Roberto, Richter, G. Stefan, Oh, So-Young, Garufi, Gabriella, Maier, Hannah, Drews, Ashley L, Stockbauer, Kathryn E, Cernoch, Patricia, Schneewind, Olaf, Olsen, Randall J, Musser, James M

“…* Context.--Ten years ago a bioterrorism event involving Bacillus anthracis spores captured the nation's interest, stimulated extensive new research on this…”
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Substitution of cysteine 192 in a highly conserved Streptococcus pyogenes extracellular cysteine protease (interleukin 1beta convertase) alters proteolytic activity and ablates zymogen processing by MUSSER, J. M, STOCKBAUER, K, KAPUR, V, RUDGERS, G. W, FISCHETTI, V. A

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Characterization of group A Streptococcus strains recovered from Mexican children with pharyngitis by automated DNA sequencing of virulence-related genes: unexpectedly large variation in the gene (sic) encoding a complement-inhibiting protein by PEREA MEJIA, L. M, STOCKBAUER, K. E, PAN, X, CRAVIOTO, A, MUSSER, J. M

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Mechanisms of Bordetella pathogenesis: Gene regulation and type III secretion-induced cytotoxicity by Stockbauer, Kathryn Elizabeth

“…Pathogenic bacteria have evolved intricate mechanisms to colonize and replicate within their desired host. The Bordetella BvgAS signal transduction system…”
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A natural variant of the cysteine protease virulence factor of group A Streptococcus with an arginine-glycine-aspartic acid (RGD) motif preferentially binds human integrins α v β 3 and α IIb β 3 by Stockbauer, Kathryn E., Magoun, Loranne, Liu, Mengyao, Burns, Eugene H., Gubba, Siddeswar, Renish, Sarah, Pan, Xi, Bodary, Sarah C., Baker, Elizabeth, Coburn, Jenifer, Leong, John M., Musser, James M.

“…The human pathogenic bacterium group A Streptococcus produces an extracellular cysteine protease [streptococcal pyrogenic exotoxin B (SpeB)] that is a critical…”
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Origin and Interstate Spread of a New York City Multidrug-Resistant Mycobacterium tuberculosis Clone Family by Bifani, Pablo J, Plikaytis, Bonnie B, Kapur, Vivek, Stockbauer, Kathryn, Pan, Xi, Lutfey, Michael L, Moghazeh, Soraya L, Eisner, William, Daniel, Thomas M, Kaplan, Mark H, Crawford, Jack T, Musser, James M, Kreiswirth, Barry N

“…Objective.—To determine whether isolates of Mycobacterium tuberculosis from New York and elsewhere that are resistant to four or more primary antimicrobial…”
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Subspecific differentiation of Mycobacterium avium complex strains by automated sequencing of a region of the gene (hsp65) encoding a 65-kilodalton heat shock protein by Swanson, D S, Kapur, V, Stockbauer, K, Pan, X, Frothingham, R, Musser, J M

“…To develop a strategy for rapid species assignment and strain differentiation of Mycobacterium avium complex (MAC) organisms, the sequence of a 360-bp region…”
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