Search Results - "Stock, Ariel"

Neuropsychiatric lupus: new mechanistic insights and future treatment directions by Schwartz, Noa, Stock, Ariel D., Putterman, Chaim

“…Patients with systemic lupus erythematosus (SLE) frequently show symptoms of central nervous system (CNS) involvement, termed neuropsychiatric SLE (NPSLE). The…”
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Managing a Specialty Service During the COVID-19 Crisis: Lessons From a New York City Health System by Ammar, Adam, Stock, Ariel D., Holland, Ryan, Gelfand, Yaroslav, Altschul, David

“…The COVID-19 pandemic has stretched health care resources to a point of crisis throughout the world. To answer the call for care, health care workers in a…”
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Mechanisms of neuropsychiatric lupus: The relative roles of the blood-cerebrospinal fluid barrier versus blood-brain barrier by Gelb, Sivan, Stock, Ariel D., Anzi, Shira, Putterman, Chaim, Ben-Zvi, Ayal

“…The pathogenesis of neuropsychiatric lupus (NPSLE) is believed to include the entry of circulating neuropathic antibodies to the brain via a pathologically…”
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The Blood Brain Barrier and Neuropsychiatric Lupus: New perspectives in light of advances in understanding the neuroimmune interface by Stock, Ariel D, Gelb, Sivan, Pasternak, Ofer, Ben-Zvi, Ayal, Putterman, Chaim

“…Abstract Experts have previously postulated a linkage between lupus associated vascular pathology and abnormal brain barriers in the immunopathogenesis of…”
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CXCL13 Neutralization Attenuates Neuropsychiatric Manifestations in Lupus-Prone Mice by Huang, Michelle W, Stock, Ariel D, Putterman, Chaim

“…Neuropsychiatric lupus (NPSLE), the nervous system presentation of systemic lupus erythematosus (SLE), remains challenging to treat due to its unclear…”
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Neuropsychiatric Lupus, the Blood Brain Barrier, and the TWEAK/Fn14 Pathway by Stock, Ariel D, Wen, Jing, Putterman, Chaim

“…Patients with systemic lupus erythematosus (SLE) can experience acute neurological events such as seizures, cerebrovascular accidents, and delirium,…”
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A Distinct T Follicular Helper Cell Subset Infiltrates the Brain in Murine Neuropsychiatric Lupus by Jain, Shweta, Stock, Ariel, Macian, Fernando, Putterman, Chaim

“…Neuropsychiatric symptoms in systemic lupus erythematosus (SLE) are not uncommon, yet the mechanisms underlying disease initiation and progression in the brain…”
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The role of B cells and autoantibodies in neuropsychiatric lupus by Wen, Jing, Stock, Ariel D, Chalmers, Samantha A, Putterman, Chaim

“…Abstract The central nervous system manifestations of SLE (neuropsychiatric lupus, NPSLE) occur frequently, though are often difficult to diagnose and treat…”
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Intracerebroventricular administration of TNF-like weak inducer of apoptosis induces depression-like behavior and cognitive dysfunction in non-autoimmune mice by Wen, Jing, Chen, Christopher Holden, Stock, Ariel, Doerner, Jessica, Gulinello, Maria, Putterman, Chaim

“…Highlights • TWEAK given ICV causes depression-like behavior and cognitive dysfunction in B6 mice. • TWEAK injection disrupts the blood brain barrier and…”
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Neuropsychiatric systemic lupus erythematosus persists despite attenuation of systemic disease in MRL/lpr mice by Stock, Ariel D, Wen, Jing, Doerner, Jessica, Herlitz, Leal C, Gulinello, Maria, Putterman, Chaim

“…Systemic lupus erythematosus (SLE) is a prototypical autoimmune disease marked by both B and T cell hyperactivity which commonly affects the joints, skin,…”
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Tertiary lymphoid structures in the choroid plexus in neuropsychiatric lupus by Stock, Ariel D, Der, Evan, Gelb, Sivan, Huang, Michelle, Weidenheim, Karen, Ben-Zvi, Ayal, Putterman, Chaim

“…The central nervous system manifestations of systemic lupus erythematosus (SLE) remain poorly understood. Given the well-defined role of autoantibodies in…”
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Aptamer‐Based Screen of Neuropsychiatric Lupus Cerebrospinal Fluid Reveals Potential Biomarkers That Overlap With the Choroid Plexus Transcriptome by Vanarsa, Kamala, Sasidharan, Prashanth, Duran, Valeria, Gokaraju, Sirisha, Nidhi, Malavika, Titus, Anto Sam Crosslee Louis Sam, Soomro, Sanam, Stock, Ariel D., Der, Evan, Putterman, Chaim, Greenberg, Benjamin, Mok, Chi Chiu, Hanly, John G., Mohan, Chandra

“…Objective As no gold‐standard diagnostic test exists for neuropsychiatric systemic lupus erythematosus (NPSLE), we undertook this study to execute a broad…”
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TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice by Wen, Jing, Doerner, Jessica, Weidenheim, Karen, Xia, Yumin, Stock, Ariel, Michaelson, Jennifer S, Baruch, Kuti, Deczkowska, Aleksandra, Gulinello, Maria, Schwartz, Michal, Burkly, Linda C, Putterman, Chaim

“…Abstract Neuropsychiatric disease is one of the most common manifestations of human systemic lupus erythematosus, but the mechanisms remain poorly understood…”
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A Novel Microglia-Specific Transcriptional Signature Correlates With Behavioral Deficits in Neuropsychiatric Lupus by Makinde, Hadijat M, Winter, Deborah R, Procissi, Daniele, Mike, Elise V, Stock, Ariel D, Kando, Mary J, Gadhvi, Gaurav T, Droho, Steven, Bloomfield, Christina L, Dominguez, Salina T, Mayr, Maximilian G, Lavine, Jeremy A, Putterman, Chaim, Cuda, Carla M

“…Neuropsychiatric symptoms of systemic lupus erythematosus (NP-SLE) affect over one-half of SLE patients, yet underlying mechanisms remain largely unknown. We…”
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Neuropsychiatric Systemic Lupus Erythematosus Is Dependent on Sphingosine-1-Phosphate Signaling by Mike, Elise V, Makinde, Hadijat M, Der, Evan, Stock, Ariel, Gulinello, Maria, Gadhvi, Gaurav T, Winter, Deborah R, Cuda, Carla M, Putterman, Chaim

“…About 40% of patients with systemic lupus erythematosus experience diffuse neuropsychiatric manifestations, including impaired cognition and depression…”
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Highly selective inhibition of Bruton's tyrosine kinase attenuates skin and brain disease in murine lupus by Chalmers, Samantha A, Wen, Jing, Doerner, Jessica, Stock, Ariel, Cuda, Carla M, Makinde, Hadijat M, Perlman, Harris, Bosanac, Todd, Webb, Deborah, Nabozny, Gerald, Fine, Jay S, Klein, Elliott, Ramanujam, Meera, Putterman, Chaim

“…Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects different end organs, including skin and brain. We and others have previously…”
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COVID-19 Infection Among Healthcare Workers: Serological Findings Supporting Routine Testing by Stock, Ariel D., Bader, Edward R., Cezayirli, Phillip, Inocencio, Julio, Chalmers, Samantha A., Yassari, Reza, Yanamadala, Vijay, Eskandar, Emad

“…A growing body of evidence demonstrates that asymptomatic and pre-symptomatic transmission of SARS-CoV-2 is a major contributor to the COVID-19 pandemic…”
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Distinct pathological patterns in relapsing–remitting and chronic models of experimental autoimmune enchephalomyelitis and the neuroprotective effect of glatiramer acetate by Aharoni, Rina, Vainshtein, Anya, Stock, Ariel, Eilam, Raya, From, Renana, Shinder, Vera, Arnon, Ruth

“…Abstract The respective roles of inflammatory and neurodegenerative processes in the pathology of multiple sclerosis (MS) and in its animal model experimental…”
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Neutralizing CXCL13 attenuates neuropsychiatric manifestations in lupus-prone mice by Huang, Michelle, Stock, Ariel D, Putterman, Chaim

“…Abstract The pathogenesis of neuropsychiatric systemic lupus erythematosus (NPSLE) remains unclear, despite the large number of lupus patients affected by…”
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BURNING SKIN-SYSTEMIC THROMBOEMBOLISM IN SYSTEMIC LUPUS ERYTHEMATOSUS by Clark, Rachel, Wiley, Karlo, Stock, Ariel, Kazmi, Mahmood, Sanina, Cristina

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