Search Results - "Stock, A. M."
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TWO-COMPONENT SIGNAL TRANSDUCTION
Published in Annual review of biochemistry (01-01-2000)“…Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine protein…”
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The Catalytic Pathway of Cytochrome P450cam at Atomic Resolution
Published in Science (American Association for the Advancement of Science) (03-03-2000)“…Members of the cytochrome P450 superfamily catalyze the addition of molecular oxygen to nonactivated hydrocarbons at physiological temperature-a reaction that…”
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Protein phosphorylation and regulation of adaptive responses in bacteria
Published in Microbiological reviews (01-12-1989)“…Bacteria continuously adapt to changes in their environment. Responses are largely controlled by signal transduction systems that contain two central enzymatic…”
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Phosphorylation of Bacterial Response Regulator Proteins by Low Molecular Weight Phospho-Donors
Published in Proceedings of the National Academy of Sciences - PNAS (15-01-1992)“…Bacterial motility and gene expression are controlled by a family of phosphorylated response regulators whose activities are modulated by an associated family…”
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Identification of the site of phosphorylation of the chemotaxis response regulator protein, CheY
Published in The Journal of biological chemistry (25-12-1989)“…The protein (Escherichia coli CheY) that controls the direction of flagellar rotation during bacterial Chemotaxis has been shown to be phosphorylated on the…”
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Histidine kinases and response regulator proteins in two-component signaling systems
Published in Trends in Biochemical Sciences (01-06-2001)“…Phosphotransfer-mediated signaling pathways allow cells to sense and respond to environmental stimuli. Autophosphorylating histidine protein kinases provide…”
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Signal transduction in bacteria
Published in Nature (London) (29-03-1990)“…Cells display a remarkable ability to respond to small fluctuations in their surroundings. In simple microbial systems, information from sensory receptors…”
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Structural Analysis and Solution Studies of the Activated Regulatory Domain of the Response Regulator ArcA: A Symmetric Dimer Mediated by the alpha 4- beta 5- alpha 5 Face
Published in Journal of molecular biology (27-05-2005)“…Escherichia coli react to changes from aerobic to anaerobic conditions of growth using the ArcA-ArcB two-component signal transduction system. This system, in…”
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A Nonlinear Stimulus-Response Relation in Bacterial Chemotaxis
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-1999)Get full text
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Structure of a Cholesterol-Binding Protein Deficient in Niemann-Pick Type C2 Disease
Published in Proceedings of the National Academy of Sciences - PNAS (04-03-2003)“…Niemann-Pick disease type C2 (NP-C2) is a fatal hereditary disease characterized by accumulation of low-density lipoprotein-derived cholesterol in lysosomes…”
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Roles of the highly conserved aspartate and lysine residues in the response regulator of bacterial chemotaxis
Published in The Journal of biological chemistry (05-05-1991)“…The chemotactic responses of bacteria such as Escherichia coli and Salmonella typhimurium are mediated by phosphorylation of the CheY protein. Phospho-CheY…”
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Divalent metal ion binding to the CheY protein and its significance to phosphotransfer in bacterial chemotaxis
Published in Biochemistry (Easton) (12-06-1990)“…Signal transduction in bacterial chemotaxis involves transfer of a phosphoryl group between the cytoplasmic proteins CheA and CheY. In addition to the…”
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Synthesis and Biochemical Characterization of a Phosphorylated Analogue of the Response Regulator CheB
Published in Biochemistry (Easton) (30-10-2001)“…CheB is a response regulator protein in the bacterial chemotaxis two-component signal transduction pathway. Methylesterase CheB functions together with…”
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Chemotaxis receptor recognition by protein methyltransferase CheR
Published in Nature structural biology (01-06-1998)“…Signal transduction processes commonly involve reversible covalent modifications of receptors. Bacterial chemotaxis receptors are reversibly methylated at…”
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Purification and characterization of the S-adenosylmethionine:glutamyl methyltransferase that modifies membrane chemoreceptor proteins in bacteria
Published in The Journal of biological chemistry (25-06-1987)“…The enzyme (EC 2.1.1.24) from Salmonella typhimurium that catalyzes the S-adenosylmethionine-dependent methyl esterification of glutamyl residues in membrane…”
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Signal transduction in bacterial chemotaxis
Published in The Journal of biological chemistry (05-10-1992)Get full text
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A tale of two components: a novel kinase and a regulatory switch
Published in Nature structural biology (01-08-2000)“…Histidine protein kinases and response regulators form the basis of phosphotransfer signal transduction pathways. Commonly referred to as two-component…”
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Structural relationships in the OmpR family of winged-helix transcription factors
Published in Journal of molecular biology (13-06-1997)“…OmpR, a protein that regulates expression of outer membrane porin proteins in enteric bacteria, belongs to a large family of transcription factors. These…”
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Energy Sensors for Aerotaxis in Escherichia coli: Something Old, Something New
Published in Proceedings of the National Academy of Sciences - PNAS (30-09-1997)“…Stock examines the phenomenon, called aerotaxis, which was documented over a 100 years ago by Engelmann. She also discusses a central issue that the mechanism…”
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Crystalline ribonuclease A loses function below the dynamical transition at 220 K
Published in Nature (London) (04-06-1992)“…When the dynamic properties of many different proteins are plotted as a function of temperature, biphasic behaviour is observed, with a broad transition…”
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