Search Results - "Stöckl, Lars"

An inducible null mutant murine model of Nijmegen breakage syndrome proves the essential function of NBS1 in chromosomal stability and cell viability by Demuth, Ilja, Frappart, Pierre-Olivier, Hildebrand, Gabriele, Melchers, Anna, Lobitz, Stephan, Stöckl, Lars, Varon, Raymonda, Herceg, Zdenko, Sperling, Karl, Wang, Zhao-Qi, Digweed, Martin

“…The human genetic disorder, Nijmegen breakage syndrome, is characterized by radiosensitivity, immunodeficiency, chromosomal instability and an increased risk…”
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A systematic proteomic study of irradiated DNA repair deficient Nbn-mice by Melchers, Anna, Stöckl, Lars, Radszewski, Janina, Anders, Marco, Krenzlin, Harald, Kalischke, Candy, Scholz, Regina, Jordan, Andreas, Nebrich, Grit, Klose, Joachim, Sperling, Karl, Digweed, Martin, Demuth, Ilja

“…The NBN gene codes for the protein nibrin, which is involved in the detection and repair of DNA double strand breaks (DSBs). The NBN gene is essential in…”
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Mild Nijmegen breakage syndrome phenotype due to alternative splicing by Varon, Raymonda, Dutrannoy, Véronique, Weikert, Georg, Tanzarella, Caterina, Antoccia, Antonio, Stöckl, Lars, Spadoni, Emanuela, Krüger, Lars-Arne, Masi, Alessandra di, Sperling, Karl, Digweed, Martin, Maraschio, Paola

“…Hypomorphic mutations of the NBS1 gene are responsible for Nijmegen breakage syndrome (NBS), characterized by microcephaly, chromosomal instability,…”
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Fully human glyco-optimized recombinant FSH (follitropin epsilon) – a randomized, comparator-controlled phase II clinical trial by Griesinger, Georg, Dietrich, Bruno, Stöckl, Lars, Eckert, Kelvin, Goletz, Steffen, Tandler-Schneider, Andreas

“…The study aimed to determine the standard treatment dose of follitropin epsilon for ovarian stimulation in the context of IVF treatment. A total of 247 women…”
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A new fully human recombinant FSH (follitropin epsilon): two phase I randomized placebo and comparator-controlled pharmacokinetic and pharmacodynamic trials by Abd-Elaziz, Khalid, Duijkers, Ingrid, Stöckl, Lars, Dietrich, Bruno, Klipping, Christine, Eckert, Kelvin, Goletz, Steffen

“…Abstract STUDY QUESTION What are the differences and similarities of pharmacokinetic (PK) and pharmacodynamic (PD) characteristics of the novel recombinant…”
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Integrity of c-Raf-1 MEK signal transduction cascade is essential for hepatitis B virus gene expression by STÖCKL, Lars, BERTING, Andreas, MALKOWSKI, Beate, FOERSTE, Ramona, HOFSCHNEIDER, Peter Hans, HILDT, Eberhard

“…The genome of hepatitis B virus (HBV) encodes two transcriptional activators: the HBx protein and the PreS2-activator large surface protein (LHBs). Both…”
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Correction: A Systematic Proteomic Study of Irradiated DNA Repair Deficient Nbn-Mice by Melchers, Anna, Stöckl, Lars, Radszewski, Janina, Anders, Marco, Krenzlin, Harald, Kalischke, Candy, Scholz, Regina, Jordan, Andreas, Nebrich, Grit, Klose, Joachim, Sperling, Karl, Digweed, Martin, Demuth, Ilja

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Correction: A Systematic Proteomic Study of Irradiated DNA Repair Deficient -Mice by Anna Melchers, Lars Stöckl, Janina Radszewski, Marco Anders, Harald Krenzlin, Candy Kalischke, Regina Scholz, Andreas Jordan, Grit Nebrich, Joachim Klose, Karl Sperling, Martin Digweed, Ilja Demuth

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A novel system for efficient gene transfer into primary human hepatocytes via cell-permeable hepatitis B virus-like particle by BRANDENBURG, Boerries, STOCKL, Lars, GUTZEIT, Cindy, ROOS, Martin, LUPBERGER, Joachim, SCHWARTLANDER, Ruth, GELDERBLOM, Hans, SAUER, Igor M, HOFSCHNEIDER, Peter Hans, HILDT, Eberhard

“…Protein transduction domains (PTDs) have been used to deliver a variety of biologically active cargo across cellular membranes. However the potential of PTDs…”
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