Search Results - "Stival, Cintia"
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Sperm Capacitation and Acrosome Reaction in Mammalian Sperm
Published in Advances in anatomy, embryology and cell biology (01-01-2016)“…Physiological changes that endow mammalian sperm with fertilizing capacity are known as sperm capacitation. As part of capacitation, sperm develop an…”
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2
Lysine acetylation modulates mouse sperm capacitation
Published in Scientific reports (06-09-2018)“…Mammalian sperm are unable to fertilize the egg immediately after ejaculation. To gain fertilization competence, they need to undergo a series of modifications…”
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3
Disruption of protein kinase A localization induces acrosomal exocytosis in capacitated mouse sperm
Published in The Journal of biological chemistry (15-06-2018)“…Protein kinase A (PKA) is a broad-spectrum Ser/Thr kinase involved in the regulation of several cellular activities. Thus, its precise activation relies on…”
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Src Kinase Is the Connecting Player between Protein Kinase A (PKA) Activation and Hyperpolarization through SLO3 Potassium Channel Regulation in Mouse Sperm
Published in The Journal of biological chemistry (24-07-2015)“…Plasma membrane hyperpolarization is crucial for mammalian sperm to acquire acrosomal responsiveness during capacitation. Among the signaling events leading to…”
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Membrane Potential Assessment by Fluorimetry as a Predictor Tool of Human Sperm Fertilizing Capacity
Published in Frontiers in cell and developmental biology (17-01-2020)“…Mammalian sperm acquire the ability to fertilize eggs by undergoing a process known as capacitation. Capacitation is triggered as the sperm travels through the…”
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A versatile kinase mobility shift assay (KiMSA) for PKA analysis and cyclic AMP detection in sperm physiology (and beyond)
Published in Frontiers in cell and developmental biology (20-02-2024)“…The cAMP-dependent protein kinase (PKA) is one of the most extensively distributed kinases among intracellular signal cascades, with a pivotal role in the…”
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Male Decapacitation Factor SPINK3 Blocks Membrane Hyperpolarization and Calcium Entry in Mouse Sperm
Published in Frontiers in cell and developmental biology (30-09-2020)“…Mammalian sperm acquire ability to fertilize through a process called capacitation, occurring after ejaculation and regulated by both female molecules and male…”
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Determination of a Robust Assay for Human Sperm Membrane Potential Analysis
Published in Frontiers in cell and developmental biology (11-06-2019)“…Mammalian sperm must undergo a complex process called capacitation in order to fertilize the egg. During this process, hyperpolarization of the sperm plasma…”
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Quantification of Protein Kinase A (PKA) Activity by an in vitro Radioactive Assay Using the Mouse Sperm Derived Enzyme
Published in Bio-protocol (20-06-2020)“…In order to acquire fertilizing potential, mammalian sperm must undergo a process known as , which relies on the early activation of Protein Kinase A (PKA)…”
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Everything you ever wanted to know about PKA regulation and its involvement in mammalian sperm capacitation
Published in Molecular and cellular endocrinology (01-12-2020)“…The 3′, 5′-cyclic adenosine monophosphate (cAMP) dependent protein kinase (PKA) is a tetrameric holoenzyme comprising a set of two regulatory subunits (PKA-R)…”
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The sodium–proton exchangers sNHE and NHE1 control plasma membrane hyperpolarization in mouse sperm
Published in The Journal of biological chemistry (28-10-2024)“…Sperm capacitation is a complex process that takes place in the female reproductive tract and empowers mammalian sperm with the competence to fertilize an egg…”
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Cdc42 localized in the CatSper signaling complex regulates cAMP‐dependent pathways in mouse sperm
Published in The FASEB journal (01-08-2021)“…Sperm acquire the ability to fertilize in a process called capacitation and undergo hyperactivation, a change in the motility pattern, which depends on Ca2+…”
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Shaping Substrate Selectivity in a Broad-Spectrum Metallo-β-Lactamase
Published in Antimicrobial agents and chemotherapy (01-04-2018)“…Metallo-β-lactamases (MBLs) are the major group of carbapenemases produced by bacterial pathogens. The design of MBL inhibitors has been limited by, among…”
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Regulation mechanisms and implications of sperm membrane hyperpolarization
Published in Mechanisms of development (01-12-2018)“…Mammalian sperm are unable to fertilize the egg immediately after ejaculation. In order to gain fertilization competence, they need to undergo a series of…”
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