Search Results - "Stirnweiss, Anja"
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Case Report: Long-Term Survival of a Pediatric Patient With an Intra-Abdominal Undifferentiated Carcinoma of Unknown Primary
Published in Frontiers in oncology (10-05-2021)“…An 8-year and 10-month-old boy presented following 2 weeks of abdominal pain, vomiting, constipation, and rectal pain. A diffuse lower-abdominal mass was felt…”
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Targeted SMN Exon Skipping: A Useful Control to Assess In Vitro and In Vivo Splice-Switching Studies
Published in Biomedicines (14-05-2021)“…The literature surrounding the use of antisense oligonucleotides continues to grow, with new disease and mechanistic applications constantly evolving…”
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Tumor suppression by IFN regulatory factor-1 is mediated by transcriptional down-regulation of cyclin D1
Published in Cancer research (Chicago, Ill.) (01-04-2007)“…IFNs have been ascribed to mediate antitumor effects. IFN regulatory factor-1 (IRF-1) is a major target gene of IFNs. It inhibits cell proliferation and…”
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IFN regulatory factor-1 bypasses IFN-mediated antiviral effects through viperin gene induction
Published in The Journal of immunology (1950) (01-05-2010)“…Viperin is an antiviral protein whose expression is highly upregulated during viral infections via IFN-dependent and/or IFN-independent pathways. We examined…”
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Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma-an aggressive and fatal disease
Published in Oncotarget (22-12-2017)“…NUT midline carcinoma (NMC) is a rare and aggressive cancer, with survival typically less than seven months, that can arise in people of any age. Genetically,…”
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Targeting Cross-Presentation as a Route to Improve the Efficiency of Peptide-Based Cancer Vaccines
Published in Cancers (08-12-2021)“…Cross-presenting dendritic cells (DC) offer an attractive target for vaccination due to their unique ability to process exogenous antigens for presentation on…”
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T cell activation results in conformational changes in the Src family kinase Lck to induce its activation
Published in Science signaling (19-02-2013)“…The lymphocyte-specific Src family protein tyrosine kinase p56(Lck) (Lck) is essential for T cell development and activation and, hence, for adaptive immune…”
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PS1-109 IFN regulatory factor-1 bypasses IFN-mediated antiviral effects through viperin gene induction
Published in Cytokine (Philadelphia, Pa.) (01-10-2011)Get full text
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