Search Results - "Stirn, Scott"
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Explosive Hazards Identified during the Manufacture and Transportation of 1‑Bromoacetyl-3,3-dinitroazetidine (RRx-001)
Published in Organic process research & development (18-11-2022)“…On August 4, 2020, a massive chemical detonation rocked the Port of Beirut, Lebanon. This explosion, which resulted from the accidental detonation of…”
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Journal Article -
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Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate‑1 Receptor
Published in ACS medicinal chemistry letters (11-12-2014)“…APD334 was discovered as part of our internal effort to identify potent, centrally available, functional antagonists of the S1P1 receptor for use as next…”
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Effects of material degradation on the thermal stability of non-sway columns
Published 2015“…The main purpose of this study is to build upon previous post buckling research by including the effects of material degradation on column strength due to…”
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Dissertation -
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(7‑Benzyloxy-2,3-dihydro-1H-pyrrolo[1,2‑a]indol-1-yl)acetic Acids as S1P1 Functional Antagonists
Published in ACS medicinal chemistry letters (11-12-2014)“…S1P1 is a validated target for treatment of autoimmune disease, and functional antagonists with superior safety and pharmacokinetic properties are being sought…”
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Journal Article -
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(7-Benzyloxy-2,3-dihydro- 1H -pyrrolo[1,2- a ]indol-1-yl)acetic Acids as S1P 1 Functional Antagonists
Published in ACS medicinal chemistry letters (11-12-2014)Get full text
Journal Article