Search Results - "Stinnette, Torian W."

Treatment of experimental adjuvant arthritis with a novel folate receptor-targeted folic acid-aminopterin conjugate by Lu, Yingjuan, Stinnette, Torian W, Westrick, Elaine, Klein, Patrick J, Gehrke, Mark A, Cross, Vicky A, Vlahov, Iontcho R, Low, Philip S, Leamon, Christopher P

“…Folate receptor (FR)-expressing macrophages have been shown to accumulate at sites of inflammation, where they promote development of inflammatory symptoms. To…”
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Antiinflammatory Activity of a Novel Folic Acid Targeted Conjugate of the mTOR Inhibitor Everolimus by Lu, Yingjuan, Parker, Nikki, Kleindl, Paul J, Cross, Vicky A, Wollak, Kristin, Westrick, Elaine, Stinnette, Torian W, Gehrke, Mark A, Wang, Kevin, Santhapuram, Hari Krishna R, You, Fei, Hahn, Spencer J, Vaughn, Jeremy F, Klein, Patrick J, Vlahov, Iontcho R, Low, Philip S, Leamon, Christopher P

“…Folate receptor (FR)-β has been identified as a promising target for antimacrophage and antiinflammatory therapies. In the present study, we investigated…”
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Folate receptor-targeted aminopterin therapy is highly effective and specific in experimental models of autoimmune uveitis and autoimmune encephalomyelitis by Lu, Yingjuan, Wollak, Kristin N, Cross, Vicky A, Westrick, Elaine, Wheeler, Leroy W, Stinnette, Torian W, Vaughn, Jeremy F, Hahn, Spencer J, Xu, Le-Cun, Vlahov, Iontcho R, Leamon, Christopher P

“…Abstract EC0746 is a rationally designed anti-inflammatory drug conjugate consisting of a modified folic acid-based ligand linked to a γ-hydrazide analog of…”
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Synthesis and activity of folate conjugated didemnin B for potential treatment of inflammatory diseases by Henne, Walter A., Kularatne, Sumith A., Ayala-López, Wilfredo, Doorneweerd, Derek D., Stinnette, Torian W., Lu, Yingjuan, Low, Philip S.

“…A folate receptor targeted didemnin B conjugate was synthesized using a hydrophilic peptide spacer linked to folate via a releasable disulfide carbonate…”
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