Search Results - "Stimac, Monika"
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1
Gene Electrotransfer of Plasmid with Tissue Specific Promoter Encoding shRNA against Endoglin Exerts Antitumor Efficacy against Murine TS/A Tumors by Vascular Targeted Effects
Published in PloS one (24-04-2015)“…Vascular targeted therapies, targeting specific endothelial cell markers, are promising approaches for the treatment of cancer. One of the targets is endoglin,…”
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2
Multiple delivery of siRNA against endoglin into murine mammary adenocarcinoma prevents angiogenesis and delays tumor growth
Published in PloS one (05-03-2013)“…Endoglin is a transforming growth factor-β (TGF- β) co-receptor that participates in the activation of a signaling pathway that mediates endothelial cell…”
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Journal Article -
3
Endoglin silencing has significant antitumor effect on murine mammary adenocarcinoma mediated by vascular targeted effect
Published in Current gene therapy (01-01-2015)“…New targets and therapeutic approaches for vascular targeted strategies in oncology are continuously explored. Endoglin, a co-receptor of TGF-β, is a known…”
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4
Electrotransfer parameters as a tool for controlled and targeted gene expression in skin
Published in Molecular therapy. Nucleic acids (2016)“…Skin is an attractive target for gene electrotransfer. It consists of different cell types that can be transfected, leading to various responses to gene…”
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5
Adjuvant TNF-α therapy to electrochemotherapy with intravenous cisplatin in murine sarcoma exerts synergistic antitumor effectiveness
Published in Radiology and oncology (01-03-2015)“…Background. Electrochemotherapy is a tumour ablation modality, based on electroporation of the cell membrane, allowing non-permeant anticancer drugs to enter…”
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6
Endoglin (CD105) Silencing Mediated by shRNA Under the Control of Endothelin-1 Promoter for Targeted Gene Therapy of Melanoma
Published in Molecular therapy. Nucleic acids (05-05-2015)“…Endoglin (CD105), a transforming growth factor (TGF)-β coreceptor, and endothelin-1, a vasoconstrictor peptide, are both overexpressed in tumor endothelial and…”
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7
Abstract 1381: The vascular targeted and antitumor effects of gene electrotransfer of plasmid silencing endoglin with tissue specific and constitutive promoter
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Endoglin, the transforming growth factor-β (TGF-β) co-receptor, mediates proliferation, differentiation and migration of endothelial cells forming…”
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8
Magnetic field contributes to the cellular uptake for effective therapy with magnetofection using plasmid DNA encoding against Mcam in B16F10 melanoma in vivo
Published in Nanomedicine (London, England) (01-03-2016)“…We explored the distribution and cellular uptake of intratumorally injected SPIONs-PAA-PEI-pDNA (magnetofection complexes), and antitumor effectiveness of…”
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9
Electrotransfer of Plasmid DNA Encoding an Anti-Mouse Endoglin (CD105) shRNA to B16 Melanoma Tumors with Low and High Metastatic Potential Results in Pronounced Anti-Tumor Effects
Published in Cancers (24-12-2015)“…Endoglin overexpression is associated with highly proliferative tumor endothelium and also with some tumors, including melanoma. Its targeting has anti-tumor…”
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10
Bystander Effect Induced by Electroporation is Possibly Mediated by Microvesicles and Dependent on Pulse Amplitude, Repetition Frequency and Cell Type
Published in The Journal of membrane biology (01-10-2016)“…Bystander effect, a known phenomenon in radiation biology, where irradiated cells release signals which cause damage to nearby, unirradiated cells, has not…”
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11
Gene Electrotransfer of Canine Interleukin 12 into Canine Melanoma Cell Lines
Published in The Journal of membrane biology (01-10-2015)“…A gene electrotransfer (GET) of interleukin 12 (IL-12) had already given good results when treating tumors in human and veterinary clinical trials. So far,…”
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12
Magnetic field contributes to the cellular uptake for effective therapy with magnetofection using plasmid DNA encoding against
Published in Nanomedicine (London, England) (01-03-2016)“…We explored the distribution and cellular uptake of intratumorally injected SPIONs-PAA-PEI-pDNA (magnetofection complexes), and antitumor effectiveness of…”
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Journal Article -
13
Gene Electrotransfer of Plasmid with Tissue Specific Promoter Encoding shRNA against Endoglin Exerts Antitumor Efficacy against Murine TS/A Tumors by Vascular Targeted Effects: e0124913
Published in PloS one (01-04-2015)“…Vascular targeted therapies, targeting specific endothelial cell markers, are promising approaches for the treatment of cancer. One of the targets is endoglin,…”
Get full text
Journal Article -
14
Adjuvant TNF-[alpha] therapy to electrochemotherapy with intravenous cisplatin in murine sarcoma exerts synergistic antitumor effectiveness
Published in Radiology and oncology (01-03-2015)“…Background. Electrochemotherapy is a tumor ablation modality, based on electroporation of the cell membrane, allowing non-permeant anticancer drugs to enter…”
Get full text
Journal Article -
15
Multiple Delivery of siRNA against Endoglin into Murine Mammary Adenocarcinoma Prevents Angiogenesis and Delays Tumor Growth. e58723
Published in PloS one (01-03-2013)“…Endoglin is a transforming growth factor- beta (TGF- beta ) co-receptor that participates in the activation of a signaling pathway that mediates endothelial…”
Get full text
Journal Article