Search Results - "Still, D"
-
1
Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation
Published in Molecular cell (18-05-2017)“…Monomethylation of histone H3 at lysine 4 (H3K4me1) and acetylation of histone H3 at lysine 27 (H3K27ac) are correlated with transcriptionally engaged enhancer…”
Get full text
Journal Article -
2
Pharmacological Management of Obesity: An Endocrine Society Clinical Practice Guideline
Published in The journal of clinical endocrinology and metabolism (01-02-2015)“…Objective: To formulate clinical practice guidelines for the pharmacological management of obesity. Participants: An Endocrine Society-appointed Task Force of…”
Get full text
Journal Article -
3
Clinical Practice Guidelines for the Perioperative Nutrition, Metabolic, and Nonsurgical Support of Patients Undergoing Bariatric Procedures – 2019 Update: Cosponsored by American Association of Clinical Endocrinologists/American College of Endocrinology, The Obesity Society, American Society for Metabolic and Bariatric Surgery, Obesity Medicine Association, and American Society of Anesthesiologists
Published in Obesity (Silver Spring, Md.) (01-04-2020)“…Objective The development of these updated clinical practice guidelines (CPGs) was commissioned by the American Association of Clinical Endocrinologists…”
Get full text
Journal Article -
4
Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease
Published in Proceedings of the National Academy of Sciences - PNAS (27-09-2011)“…Insulin resistance is associated with nonalcoholic fatty liver disease (NAFLD) and is a major factor in the pathogenesis of type 2 diabetes. The development of…”
Get full text
Journal Article -
5
Effects of glucagon-like peptide-1 receptor agonists on upper endoscopy in diabetic and nondiabetic patients
Published in Gastrointestinal endoscopy (01-10-2024)“…Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) promote weight loss by suppressing appetite, enhancing satiety, regulating glucose metabolism, and…”
Get full text
Journal Article -
6
Body mass index and all‐cause mortality among older adults
Published in Obesity (Silver Spring, Md.) (01-10-2016)“…Objective To examine the association between baseline body mass index (BMI, kg/m2) and all‐cause mortality in a well‐characterized cohort of older persons…”
Get full text
Journal Article -
7
A Role for Fibroblast Growth Factor 19 and Bile Acids in Diabetes Remission After Roux-en-Y Gastric Bypass
Published in Diabetes care (01-07-2013)“…Roux-en-Y gastric bypass (RYGB) in humans can remit type 2 diabetes, but the operative mechanism is not completely understood. In mice, fibroblast growth…”
Get full text
Journal Article -
8
Preoperative prediction of type 2 diabetes remission after Roux-en-Y gastric bypass surgery: a retrospective cohort study
Published in The lancet. Diabetes & endocrinology (2014)“…Summary Background About 60% of patients with type 2 diabetes achieve remission after Roux-en-Y gastric bypass (RYGB) surgery. No accurate method is available…”
Get full text
Journal Article -
9
AEBP1 expression increases with severity of fibrosis in NASH and is regulated by glucose, palmitate, and miR-372-3p
Published in PloS one (12-07-2019)“…Factors governing the development of liver fibrosis in nonalcoholic steatohepatitis (NASH) are only partially understood. We recently identified adipocyte…”
Get full text
Journal Article -
10
Effects of sustained weight loss on outcomes associated with obesity comorbidities and healthcare resource utilization
Published in PloS one (03-11-2021)“…Determine the impact of long-term non-surgical weight loss maintenance on clinical relevance for osteoarthritis, cancer, opioid use, and depression/anxiety and…”
Get full text
Journal Article -
11
Prospective Study of Diet Quality and the Risk of Dementia in the Oldest Old
Published in Nutrients (01-03-2023)“…This study examined the associations between overall diet quality and the risk of dementia in a rural cohort among the oldest old. Included in this prospective…”
Get full text
Journal Article -
12
CCL20 is up-regulated in non-alcoholic fatty liver disease fibrosis and is produced by hepatic stellate cells in response to fatty acid loading
Published in Journal of translational medicine (24-04-2018)“…Nonalcoholic fatty liver disease (NAFLD) is a prevalent complication of extreme obesity. Loading of the liver with fat can progress to inflammation and…”
Get full text
Journal Article -
13
Collimation with hollow electron beams
Published in Physical review letters (17-08-2011)“…A novel concept of controlled halo removal for intense high-energy beams in storage rings and colliders is presented. It is based on the interaction of the…”
Get full text
Journal Article -
14
Walking Tall: A Narrative Critical Family History of a Grandmother’s Fight for New Normals
Published in Genealogy (Basel) (01-06-2020)“…In this genealogical narrative, the author researches her deceased maternal grandmother Eula Mae’s life and explores ways that various events created the…”
Get full text
Journal Article -
15
Targeting Pyruvate Carboxylase Reduces Gluconeogenesis and Adiposity and Improves Insulin Resistance
Published in Diabetes (New York, N.Y.) (01-07-2013)“…We measured the mRNA and protein expression of the key gluconeogenic enzymes in human liver biopsy specimens and found that only hepatic pyruvate carboxylase…”
Get full text
Journal Article -
16
Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes
Published in Proceedings of the National Academy of Sciences - PNAS (21-07-2009)“…Fasting hyperglycemia in patients with type 2 diabetes mellitus (T2DM) is attributed to increased hepatic gluconeogenesis, which has been ascribed to increased…”
Get full text
Journal Article -
17
Gene expression profiling in subcutaneous, visceral and epigastric adipose tissues of patients with extreme obesity
Published in International Journal of Obesity (01-03-2014)“…Objective: The goal of the present study was to identify differences in gene expression between SAT, VAT and EAT depots in Class III severely obese…”
Get full text
Journal Article -
18
Transcriptomic Profiling of Obesity-Related Nonalcoholic Steatohepatitis Reveals a Core Set of Fibrosis-Specific Genes
Published in Journal of the Endocrine Society (01-07-2018)“…Abstract Nonalcoholic steatohepatitis (NASH) is strongly associated with obesity and type 2 diabetes. The molecular factors underlying the development of…”
Get full text
Journal Article -
19
Perturbations of fibroblast growth factors 19 and 21 in type 2 diabetes
Published in PloS one (09-02-2015)“…Fibroblast growth factors 19 and 21 (FGF19 and FGF21) have been implicated, independently, in type 2 diabetes (T2D) but it is not known if their circulating…”
Get full text
Journal Article -
20
Bile Acids, FXR, and Metabolic Effects of Bariatric Surgery
Published in Journal of Obesity (01-01-2016)“…Overweight and obesity represent major risk factors for diabetes and related metabolic diseases. Obesity is associated with a chronic and progressive…”
Get full text
Journal Article