Search Results - "Stilgenbauer, Linda"

Avasimibe induces CYP3A4 and multiple drug resistance protein 1 gene expression through activation of the pregnane X receptor by Sahi, Jasminder, Milad, Mark A, Zheng, Xianxian, Rose, Kelly A, Wang, Hongbing, Stilgenbauer, Linda, Gilbert, Darryl, Jolley, Summer, Stern, Ralph H, LeCluyse, Edward L

“…In vitro and clinical studies were conducted to characterize the potential of avasimibe, an acyl-CoA/cholesterol acyltransferase inhibitor to cause drug-drug…”
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Evaluation of a targeted prodrug strategy to enhance oral absorption of poorly water-soluble compounds by CHAN, O. H, SCHMID, H. L, STILGENBAUER, L. A, HOWSON, W, HORWELL, D. C, STEWART, B. H

“…The purpose of this research was to examine a targeted prodrug strategy to increase the absorption of a poorly water-soluble lipophilic compound. Three…”
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Phosphate prodrugs of PD154075 by Zhu, Z, Chen, H G, Goel, O P, Chan, O H, Stilgenbauer, L A, Stewart, B H

“…In the preparation of phosphate prodrugs of PD154075, several strategies of linking a phosphate group to the indole moiety were studied. A novel linker,…”
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EFFECTS OF AVASIMIBE ON CYTOCHROME P450 2C9 EXPRESSION IN VITRO AND IN VIVO by SAHI, Jasminder, STERN, Ralph H, LECLUYSE, Edward L, MILAD, Mark A, ROSE, Kelly A, GIBSON, Gordon, XIANXIAN ZHENG, STILGENBAUER, Linda, SADAGOPAN, Nalini, JOLLEY, Summer, GILBERT, Darryl

“…Avasimibe, an acyl-CoA:cholesterol acyltransferase inhibitor, has been previously shown to be a potent inducer of CYP3A4 and multiple drug resistance protein…”
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