Search Results - "Stijleman, Inge J."

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes by PARKER, Joel S, MULLINS, Michael, QUACKENBUSH, John F, STIJLEMAN, Inge J, PALAZZO, Juan, MARRON, J. S, NOBEL, Andrew B, MARDIS, Elaine, NIELSEN, Torsten O, ELLIS, Matthew J, PEROU, Charles M, BERNARD, Philip S, CHEANG, Maggie C. U, LEUNG, Samuel, VODUC, David, VICKERY, Tammi, DAVIES, Sherri, FAURON, Christiane, XIAPING HE, ZHIYUAN HU

“…PURPOSE To improve on current standards for breast cancer prognosis and prediction of chemotherapy benefit by developing a risk model that incorporates the…”
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Intrinsic Subtypes from PAM50 Gene Expression Assay in a Population-Based Breast Cancer Cohort: Differences by Age, Race, and Tumor Characteristics by SWEENEY, Carol, BERNARD, Philip S, EBBERT, Mark T. W, CASTILLO, Adrienne, KUSHI, Lawrence H, CAAN, Bette J, FACTOR, Rachel E, KWAN, Marilyn L, HABEL, Laurel A, QUESENBERRY, Charles P, SHAKESPEAR, Kaylynn, WELTZIEN, Erin K, STIJLEMAN, Inge J, DAVIS, Carole A

“…Data are lacking to describe gene expression-based breast cancer intrinsic subtype patterns for population-based patient groups. We studied a diverse cohort of…”
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Responsiveness of Intrinsic Subtypes to Adjuvant Anthracycline Substitution in the NCIC.CTG MA.5 Randomized Trial by CHEANG, Maggie C. U, DAVID VODUC, K, STIJLEMAN, Inge J, DAVIS, Carole, EBBERT, MarkT W, PARKER, Joel S, ELLIS, Matthew J, BERNARD, Philip S, PEROU, Charles M, NIELSEN, Torsten O, DONGSHENG TU, SHAN JIANG, LEUNG, Samuel, CHIA, Stephen K, SHEPHERD, Lois E, LEVINE, Mark N, PRITCHARD, Kathleen I, DAVIES, Sherri

“…Recent studies suggest that intrinsic breast cancer subtypes may differ in their responsiveness to specific chemotherapy regimens. We examined this hypothesis…”
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Lack of effect of metformin on mammary carcinogenesis in nondiabetic rat and mouse models by Thompson, Matthew D, Grubbs, Clinton J, Bode, Ann M, Reid, Joel M, McGovern, Renee, Bernard, Philip S, Stijleman, Inge J, Green, Jeffrey E, Bennett, Christina, Juliana, M Margaret, Moeinpour, Fariba, Steele, Vernon E, Lubet, Ronald A

“…Epidemiologic studies have shown that diabetics receiving the biguanide metformin, as compared with sulfonylureas or insulin, have a lower incidence of breast…”
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Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes by DeRose, Yoko S, Wang, Guoying, Lin, Yi-Chun, Bernard, Philip S, Buys, Saundra S, Ebbert, Mark T W, Factor, Rachel, Matsen, Cindy, Milash, Brett A, Nelson, Edward, Neumayer, Leigh, Randall, R Lor, Stijleman, Inge J, Welm, Bryan E, Welm, Alana L

“…By implementing the conditions for orthotopic implantation of different types of human breast tumors, the authors have created a publicly available bank of new…”
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A Comparison of PAM50 Intrinsic Subtyping with Immunohistochemistry and Clinical Prognostic Factors in Tamoxifen-Treated Estrogen Receptor-Positive Breast Cancer by NIELSEN, Torsten O, PARKER, Joel S, CHEANG, Maggie C. U, MARDIS, Elaine R, PEROU, Charles M, BERNARD, Philip S, ELLIS, Matthew J, LEUNG, Samuel, VODUC, David, EBBERT, Mark, VICKERY, Tammi, DAVIES, Sherri R, SNIDER, Jacqueline, STIJLEMAN, Inge J, REED, Jerry

“…To compare clinical, immunohistochemical (IHC), and gene expression models of prognosis applicable to formalin-fixed, paraffin-embedded blocks in a large…”
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Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes by Parker, Joel S, Mullins, Michael, Cheang, Maggie C U, Leung, Samuel, Voduc, David, Vickery, Tammi, Davies, Sherri, Fauron, Christiane, He, Xiaping, Hu, Zhiyuan, Quackenbush, John F, Stijleman, Inge J, Palazzo, Juan, Marron, J S, Nobel, Andrew B, Mardis, Elaine, Nielsen, Torsten O, Ellis, Matthew J, Perou, Charles M, Bernard, Philip S

“…To improve on current standards for breast cancer prognosis and prediction of chemotherapy benefit by developing a risk model that incorporates the gene…”
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Membrane proteins significantly restrict exosome mobility by Skliar, Mikhail, Chernyshev, Vasiliy S., Belnap, David M., Sergey, German V., Al-Hakami, Samer M., Bernard, Philip S., Stijleman, Inge J., Rachamadugu, Rakesh

“…Exosomes are membrane nanovesicles implicated in cell-to-cell signaling in which they transfer their molecular cargo from the parent to the recipient cells…”
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PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers by Bastien, Roy R L, Rodríguez-Lescure, Álvaro, Ebbert, Mark T W, Prat, Aleix, Munárriz, Blanca, Rowe, Leslie, Miller, Patricia, Ruiz-Borrego, Manuel, Anderson, Daniel, Lyons, Bradley, Álvarez, Isabel, Dowell, Tracy, Wall, David, Seguí, Miguel Ángel, Barley, Lee, Boucher, Kenneth M, Alba, Emilio, Pappas, Lisa, Davis, Carole A, Aranda, Ignacio, Fauron, Christiane, Stijleman, Inge J, Palacios, José, Antón, Antonio, Carrasco, Eva, Caballero, Rosalía, Ellis, Matthew J, Nielsen, Torsten O, Perou, Charles M, Astill, Mark, Bernard, Philip S, Martín, Miguel

“…Many methodologies have been used in research to identify the "intrinsic" subtypes of breast cancer commonly known as Luminal A, Luminal B, HER2-Enriched…”
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PAM50 proliferation score as a predictor of weekly paclitaxel benefit in breast cancer by Martín, Miguel, Prat, Aleix, Rodríguez-Lescure, Álvaro, Caballero, Rosalía, Ebbert, Mark T. W., Munárriz, Blanca, Ruiz-Borrego, Manuel, Bastien, Roy R. L., Crespo, Carmen, Davis, Carole, Rodríguez, César A., López-Vega, José M., Furió, Vicente, García, Ana M., Casas, Maribel, Ellis, Matthew J., Berry, Donald A., Pitcher, Brandelyn N., Harris, Lyndsay, Ruiz, Amparo, Winer, Eric, Hudis, Clifford, Stijleman, Inge J., Tuck, David P., Carrasco, Eva, Perou, Charles M., Bernard, Philip S.

“…To identify a group of patients who might benefit from the addition of weekly paclitaxel to conventional anthracycline-containing chemotherapy as adjuvant…”
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Reparameterization of PAM50 Expression Identifies Novel Breast Tumor Dimensions and Leads to Discovery of a Genome-Wide Significant Breast Cancer Locus at 12q15 by Madsen, Michael J, Knight, Stacey, Sweeney, Carol, Factor, Rachel, Salama, Mohamed, Stijleman, Inge J, Rajamanickam, Venkatesh, Welm, Bryan E, Arunachalam, Sasi, Jones, Brandt, Rachamadugu, Rakesh, Rowe, Kerry, Cessna, Melissa H, Thomas, Alun, Kushi, Lawrence H, Caan, Bette J, Bernard, Philip S, Camp, Nicola J

“…Breast tumor subtyping has failed to provide impact in susceptibility genetics. The PAM50 assay categorizes breast tumors into: Luminal A, Luminal B,…”
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Breastfeeding, PAM50 tumor subtype, and breast cancer prognosis and survival by Kwan, Marilyn L, Bernard, Philip S, Kroenke, Candyce H, Factor, Rachel E, Habel, Laurel A, Weltzien, Erin K, Castillo, Adrienne, Gunderson, Erica P, Maxfield, Kaylynn S, Stijleman, Inge J, Langholz, Bryan M, Quesenberry, Jr, Charles P, Kushi, Lawrence H, Sweeney, Carol, Caan, Bette J

“…Breastfeeding is associated with decreased breast cancer risk, yet associations with prognosis and survival by tumor subtype are largely unknown. We conducted…”
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Chemoprevention with Cyclooxygenase and Epidermal Growth Factor Receptor Inhibitors in Familial Adenomatous Polyposis Patients: mRNA Signatures of Duodenal Neoplasia by Delker, Don A, Wood, Austin C, Snow, Angela K, Samadder, N Jewel, Samowitz, Wade S, Affolter, Kajsa E, Boucher, Kenneth M, Pappas, Lisa M, Stijleman, Inge J, Kanth, Priyanka, Byrne, Kathryn R, Burt, Randall W, Bernard, Philip S, Neklason, Deborah W

“…To identify gene expression biomarkers and pathways targeted by sulindac and erlotinib given in a chemoprevention trial with a significant decrease in duodenal…”
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Association of high obesity with PAM50 breast cancer intrinsic subtypes and gene expression by Kwan, Marilyn L, Kroenke, Candyce H, Sweeney, Carol, Bernard, Philip S, Weltzien, Erin K, Castillo, Adrienne, Factor, Rachel E, Maxfield, Kaylynn S, Stijleman, Inge J, Kushi, Lawrence H, Quesenberry, Jr, Charles P, Habel, Laurel A, Caan, Bette J

“…Invasive breast cancers are now commonly classified using gene expression into biologically and clinically distinct tumor subtypes. However, the role of…”
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Phase II Study of Bortezomib and Pegylated Liposomal Doxorubicin in the Treatment of Metastatic Breast Cancer by Irvin, William J, Orlowski, Robert Z, Chiu, Wing-Keung, Carey, Lisa A, Collichio, Frances A, Bernard, Philip S, Stijleman, Inge J, Perou, Charles, Ivanova, Anastasia, Dees, E. Claire

“…Abstract Background Based on preclinical studies and a phase I trial of the combination of bortezomib and pegylated liposomal doxorubicin (PLD), which both…”
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Characterization of uncertainty in the classification of multivariate assays: application to PAM50 centroid-based genomic predictors for breast cancer treatment plans by Ebbert, Mark Tw, Bastien, Roy Rl, Boucher, Kenneth M, Martín, Miguel, Carrasco, Eva, Caballero, Rosalía, Stijleman, Inge J, Bernard, Philip S, Facelli, Julio C

“…Multivariate assays (MVAs) for assisting clinical decisions are becoming commonly available, but due to complexity, are often considered a high-risk approach…”
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Clinical validation of the Prosigna breast cancer prognostic gene signature assay on formalin-fixed paraffin embedded breast cancer tumors with comparison to standard molecular markers by Bastien, Roy R. L., Vaughn, Cecily, Elsberry, Danielle, Stijleman, Inge J., Bernard, Philip Seth

“…Abstract only…”
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Reparameterization of PAM50 expression identifies novel breast tumor dimensions and leads to discovery of a genomewide significant breast cancer locus at 12q15 by Madsen, Michael J, Knight, Stacey, Sweeney, Carol, Factor, Rachel, Salama, Mohamed, Stijleman, Inge J, Rajamanickam, Venkatesh, Welm, Bryan E, Arunachalam, Sasi, Jones, Brandt, Rachamadugu, Rakesh, Rowe, Kerry, Cessna, Melissa H, Thomas, Alun, Kushi, Lawrence H, Caan, Bette J, Bernard, Philip S, Camp, Nicola J

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Molecular profiling of ER weakly-positive breast cancer by Sheffield, Brandon S., Kos, Zuzana, Wang, Xiuqing, Chow, Christine, Lau, Sherman, Wolber, Robert, Gilks, Cyril Blake, Myles, Nickolas, Thomson, Thomas A., Hayes, Malcolm M., Rachamadugu, Rakesh, Stijleman, Inge J., Bernard, Philip B., Nielsen, Torsten O., Chia, Stephen K. L.

“…Abstract only…”
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Abstract LB-29: Hormonal risk factors and breast cancer prognosis and survival by PAM50 molecular subtype by Kwan, Marilyn L., Sweeney, Carol, Habel, Laurel A., Weltzien, Erin, Castillo, Adrienne, Davis, Carole, Factor, Rachel E., Kroenke, Candyce H., Shakespear, Kaylynn, Quesenberry, Charles P., Stijleman, Inge J., Bernard, Philip S., Kushi, Lawrence H., Caan, Bette J.

“…Abstract Background: Lifestyle and reproductive factors known to influence estrogen levels have been associated with breast cancer (BC) risk and prognosis…”
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