Search Results - "Stiffler"

Evolvability as a Function of Purifying Selection in TEM-1 β-Lactamase by Stiffler, Michael A., Hekstra, Doeke R., Ranganathan, Rama

“…Evolvability—the capacity to generate beneficial heritable variation—is a central property of biological systems. However, its origins and modulation by…”
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Inferring protein 3D structure from deep mutation scans by Rollins, Nathan J., Brock, Kelly P., Poelwijk, Frank J., Stiffler, Michael A., Gauthier, Nicholas P., Sander, Chris, Marks, Debora S.

“…We describe an experimental method of three-dimensional (3D) structure determination that exploits the increasing ease of high-throughput mutational scans…”
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Elevated serum measures of lipid peroxidation and abnormal prefrontal white matter in euthymic bipolar adults: toward peripheral biomarkers of bipolar disorder by Versace, A, Andreazza, A C, Young, L T, Fournier, J C, Almeida, J R C, Stiffler, R S, Lockovich, J C, Aslam, H A, Pollock, M H, Park, H, Nimgaonkar, V L, Kupfer, D J, Phillips, M L

“…Diffusion tensor imaging (DTI) studies consistently reported abnormalities in fractional anisotropy (FA) and radial diffusivity (RD), measures of the integrity…”
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Darwin Comes to the Old Northwest by Stiffler, Stuart

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Foot Angle and Loading Rate during Running Demonstrate a Nonlinear Relationship by STIFFLER-JOACHIM, MIKEL R, WILLE, CHRISTA M, KLIETHERMES, STEPHANIE A, JOHNSTON, WILLIAM, HEIDERSCHEIT, BRYAN C

“…Vertical loading rates are typically found to be lower in forefoot compared to rearfoot strikers, promoting the idea that forefoot striking is desirable and…”
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Complexity Results and Fast Methods for Optimal Tabletop Rearrangement with Overhand Grasps by Han, Shuai D, Stiffler, Nicholas M, Krontiris, Athanasios, Bekris, Kostas E, Yu, Jingjin

“…This paper studies the underlying combinatorial structure of a class of object rearrangement problems, which appear frequently in applications. The problems…”
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Revisiting the Plasmodium sporozoite inoculum and elucidating the efficiency with which malaria parasites progress through the mosquito by Kanatani, Sachie, Stiffler, Deborah, Bousema, Teun, Yenokyan, Gayane, Sinnis, Photini

“…Malaria is initiated when infected anopheline mosquitoes inoculate sporozoites as they probe for blood. It is thought that all infected mosquitoes are…”
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Factors Influencing Base of Gait During Running: Consideration of Sex, Speed, Kinematics, and Anthropometrics by Stiffler-Joachim, Mikel R, Wille, Christa, Kliethermes, Stephanie, Heiderscheit, Bryan

“…A narrow base of gait (BOG), the mediolateral distance between the foot and the body's line of gravity at midstance, during running is a suggested cause of…”
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Ayahuasca: From the Amazon to a city near you by Stiffler, J. David

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Identifying tripartite relationship among cortical thickness, neuroticism, and mood and anxiety disorders by Rozovsky, Renata, Bertocci, Michele, Iyengar, Satish, Stiffler, Richelle S., Bebko, Genna, Skeba, Alexander S., Brady, Tyler, Aslam, Haris, Phillips, Mary L.

“…The number of young adults seeking help for emotional distress, subsyndromal-syndromal mood/anxiety symptoms, including those associated with neuroticism, is…”
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PDZ Domain Binding Selectivity Is Optimized Across the Mouse Proteome by Stiffler, Michael A, Chen, Jiunn R, Grantcharova, Viara P, Lei, Ying, Fuchs, Daniel, Allen, John E, Zaslavskaia, Lioudmila A, MacBeath, Gavin

“…PDZ domains have long been thought to cluster into discrete functional classes defined by their peptide-binding preferences. We used protein microarrays and…”
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Population genomics of parallel adaptation in threespine stickleback using sequenced RAD tags by Hohenlohe, Paul A, Bassham, Susan, Etter, Paul D, Stiffler, Nicholas, Johnson, Eric A, Cresko, William A

“…Next-generation sequencing technology provides novel opportunities for gathering genome-scale sequence data in natural populations, laying the empirical…”
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Simultaneous enhancement of multiple functional properties using evolution-informed protein design by Fram, Benjamin, Su, Yang, Truebridge, Ian, Riesselman, Adam J., Ingraham, John B., Passera, Alessandro, Napier, Eve, Thadani, Nicole N., Lim, Samuel, Roberts, Kristen, Kaur, Gurleen, Stiffler, Michael A., Marks, Debora S., Bahl, Christopher D., Khan, Amir R., Sander, Chris, Gauthier, Nicholas P.

“…A major challenge in protein design is to augment existing functional proteins with multiple property enhancements. Altering several properties likely…”
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A hierarchical clustering approach for examining potential risk factors for bone stress injury in runners by Martin, Jack A., Stiffler-Joachim, Mikel R., Wille, Christa M., Heiderscheit, Bryan C.

“…Bone stress injuries (BSI) are overuse injuries that commonly occur in runners. BSI risk is multifactorial and not well understood. Unsupervised machine…”
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Lower Extremity Kinematic and Kinetic Asymmetries during Running by STIFFLER-JOACHIM, MIKEL RENEE, LUKES, DREW HENRY, KLIETHERMES, STEPHANIE A., HEIDERSCHEIT, BRYAN C.

“…Between-limb asymmetries during running are often evaluated to assess injury risk or recovery. Asymmetries less than 10% are generally considered normal, but…”
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Focal distribution of hepatitis C virus RNA in infected livers by Stiffler, J David, Nguyen, Minhhuyen, Sohn, Ji A, Liu, Chen, Kaplan, David, Seeger, Christoph

“…Hepatitis C virus (HCV) is a plus-strand RNA virus that replicates by amplification of genomic RNA from minus strands leading to accumulation of almost one…”
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Vertical Loading Rate Is Not Associated with Running Injury, Regardless of Calculation Method by SCHMIDA, ELIZABETH A., WILLE, CHRISTA M., STIFFLER-JOACHIM, MIKEL R., KLIETHERMES, STEPHANIE A., HEIDERSCHEIT, BRYAN C.

“…Loading rate (LR), the slope of the vertical ground reaction force (vGRF), is commonly used to assess running-related injury risk. However, the relationship…”
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Exploring the abelian 4D, $$ \mathcal{N} $$ = 4 vector-tensor supermultiplet and its off-shell central charge structure by Gates, S. James, Stiffler, Kory

“…An abelian 4D, $$ \mathcal{N} $$ N = 4 vector supermultiplet allows for a duality transformation to be applied to one of its spin-0 states. The resulting…”
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Running Biomechanics Before Injury and 1 Year After Anterior Cruciate Ligament Reconstruction in Division I Collegiate Athletes by Knurr, Keith A., Kliethermes, Stephanie A., Stiffler-Joachim, Mikel R., Cobian, Daniel G., Baer, Geoffrey S., Heiderscheit, Bryan C.

“…Background: Preinjury running biomechanics are an ideal comparator for quantifying recovery after anterior cruciate ligament (ACL) reconstruction (ACLR),…”
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Punk Subculture and the Queer Critique of Community on 1980s Cable TV: The Case of New Wave Theatre by Stiffler, Brad

“…If histories of television recognize it all, the relationship between punk subculture and the mass cultural medium of television is often rendered as a story…”
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