Search Results - "Stierwalt, Harrison D"

Skeletal Muscle ACSL Isoforms Relate to Measures of Fat Metabolism in Humans by STIERWALT, HARRISON D., EHRLICHER, SARAH E., ROBINSON, MATTHEW M., NEWSOM, SEAN A.

“…INTRODUCTIONEvidence from model systems implicates long-chain acyl-CoA synthetases (ACSLs) as key regulators of skeletal muscle fat oxidation and fat storage;…”
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Short-Term High-Fat Feeding Does Not Alter Mitochondrial Lipid Respiratory Capacity but Triggers Mitophagy Response in Skeletal Muscle of Mice by Ehrlicher, Sarah E, Stierwalt, Harrison D, Newsom, Sean A, Robinson, Matthew M

“…Lipid overload of the mitochondria is linked to the development of insulin resistance in skeletal muscle which may be a contributing factor to the progression…”
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Impact of 4 weeks of western diet and aerobic exercise training on whole‐body phenotype and skeletal muscle mitochondrial respiration in male and female mice by McGowan, Erin M., Ehrlicher, Sarah E., Stierwalt, Harrison D., Robinson, Matthew M., Newsom, Sean A.

“…High dietary fat intake induces significant whole‐body and skeletal muscle adaptations in mice, including increased capacity for fat oxidation and…”
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Rats with high aerobic capacity display enhanced transcriptional adaptability and upregulation of bile acid metabolism in response to an acute high‐fat diet by Stierwalt, Harrison D., Morris, E. Matthew, Maurer, Adrianna, Apte, Udayan, Phillips, Kathryn, Li, Tiangang, Meers, Grace M. E., Koch, Lauren G., Britton, Steven L., Graf, Greg, Rector, R. Scott, Mercer, Kelly, Shankar, Kartik, Thyfault, John P.

“…Rats selectively bred for the high intrinsic aerobic capacity runner (HCR) or low aerobic capacity runner (LCR) show pronounced differences in susceptibility…”
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Two weeks of high-intensity interval training increases skeletal muscle mitochondrial respiration via complex-specific remodeling in sedentary humans by Batterson, Philip M, McGowan, Erin M, Stierwalt, Harrison D, Ehrlicher, Sarah E, Newsom, Sean A, Robinson, Matthew M

“…Aerobic training remodels the quantity and quality (function per unit) of skeletal muscle mitochondria to promote substrate oxidation, however, there remain…”
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Diet and Exercise Training Influence Skeletal Muscle Long-Chain acyl-CoA Synthetases by STIERWALT, HARRISON D., EHRLICHER, SARAH E., ROBINSON, MATTHEW M., NEWSOM, SEAN A.

“…INTRODUCTIONLong-chain acyl-CoA synthetases (ACSL) are implicated as regulators of oxidation and storage of fatty acids within skeletal muscle; however, to…”
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Mitochondrial adaptations to exercise do not require Bcl2‐mediated autophagy but occur with BNIP3/Parkin activation by Ehrlicher, Sarah E., Stierwalt, Harrison D., Miller, Benjamin F., Newsom, Sean A., Robinson, Matthew M.

“…Understanding the mechanisms regulating mitochondrial respiratory function and adaptations to metabolic challenges, such as exercise and high dietary fat, is…”
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Remodeling of skeletal muscle mitochondrial proteome with high-fat diet involves greater changes to β-oxidation than electron transfer proteins in mice by Dasari, Surendra, Newsom, Sean A, Ehrlicher, Sarah E, Stierwalt, Harrison D, Robinson, Matthew M

“…Excess fat intake can increase lipid oxidation and expression of mitochondrial proteins, indicating remodeling of the mitochondrial proteome. Yet intermediates…”
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Intramuscular diacylglycerol accumulates with acute hyperinsulinemia in insulin-resistant phenotypes by McKenna, Colleen F, Stierwalt, Harrison D, Zemski Berry, Karin A, Ehrlicher, Sarah E, Robinson, Matthew M, Zarini, Simona, Kahn, Darcy E, Snell-Bergeon, Janet K, Perreault, Leigh, Bergman, Bryan C, Newsom, Sean A

“…Elevated skeletal muscle diacylglycerols (DAGs) and ceramides can impair insulin signaling, and acylcarnitines (acylCNs) reflect impaired mitochondrial fatty…”
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Long-term rates of mitochondrial protein synthesis are increased in mouse skeletal muscle with high-fat feeding regardless of insulin-sensitizing treatment by Newsom, Sean A, Miller, Benjamin F, Hamilton, Karyn L, Ehrlicher, Sarah E, Stierwalt, Harrison D, Robinson, Matthew M

“…Skeletal muscle mitochondrial protein synthesis is regulated in part by insulin. The development of insulin resistance with diet-induced obesity may therefore…”
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Substrate-Specific Respiration of Isolated Skeletal Muscle Mitochondria after 1 h of Moderate Cycling in Sedentary Adults by NEWSOM, SEAN A., STIERWALT, HARRISON D., EHRLICHER, SARAH E., ROBINSON, MATTHEW M.

“…Skeletal muscle mitochondria have dynamic shifts in oxidative metabolism to meet energy demands of aerobic exercise. Specific complexes oxidize lipid and…”
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Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish by Axton, Elizabeth R, Beaver, Laura M, St Mary, Lindsey, Truong, Lisa, Logan, Christiana R, Spagnoli, Sean, Prater, Mary C, Keller, Rosa M, Garcia-Jaramillo, Manuel, Ehrlicher, Sarah E, Stierwalt, Harrison D, Newsom, Sean A, Robinson, Matthew M, Tanguay, Robert L, Stevens, Jan F, Hord, Norman G

“…Dietary nitrate improves exercise performance by reducing the oxygen cost of exercise, although the mechanisms responsible are not fully understood. We tested…”
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Robust intrinsic differences in mitochondrial respiration and H 2 O 2 emission between L6 and C2C12 cells by Robinson, Matthew M, Sather, Bergen K, Burney, Emily R, Ehrlicher, Sarah E, Stierwalt, Harrison D, Franco, Maria Clara, Newsom, Sean A

“…Rat L6 and mouse C2C12 cell lines are commonly used to investigate myocellular metabolism. Mitochondrial characteristics of these cell lines remain poorly…”
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Skeletal muscle autophagy remains responsive to hyperinsulinemia and hyperglycemia at higher plasma insulin concentrations in insulin‐resistant mice by Ehrlicher, Sarah E., Stierwalt, Harrison D., Newsom, Sean A., Robinson, Matthew M.

“…Skeletal muscle autophagy is suppressed by insulin, but it is not clear if such suppression is altered with insulin resistance. We investigated if the…”
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Insulin‐stimulated Rac1‐GTP binding is not impaired by palmitate treatment in L6 myotubes by Stierwalt, Harrison D., Ehrlicher, Sarah E., Bergman, Bryan C., Robinson, Matthew M., Newsom, Sean A.

“…Ras‐related C3 botulinum toxin substrate 1 (Rac1) is required for normal insulin‐stimulated glucose transport in skeletal muscle and evidence indicates Rac1…”
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High-fat Diet Increases ETF Synthesis And Lipid Respiration In Muscle During Training In Female Mice: 666 by Batterson, Philip M., McGowan, Erin M., Stierwalt, Harrison D., Ehrlicher, Sarah E., Borowik, Agnieszka K., Miller, Benjamin F., Newsom, Sean A., Robinson, Matthew M.

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Long-chain Acyl-CoA Synthetases Relate To Fat Oxidation And Storage In Skeletal Muscle Of Lean Humans: 3692 Board #9 by Stierwalt, Harrison D., Ehrlicher, Sarah E., Robinson, Matthew M., Newsom, Sean A.

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No Change To Muscle Mitochondrial Fat Oxidation Or ETF Abundance Following Exercise In Healthy Adults: 609 Board #6 May 27 1:00 PM - 3:00 PM by Batterson, Philip M., Stierwalt, Harrison D., Ehrlicher, Sarah E., Robinson, Matthew M., Newsom, Sean A.

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Western Diet And Exercise Training Increase Mitochondrial Lipid Respiration In Male But Not Female Mice: 3867 Board #184 May 30 9:00 AM - 10:30 AM by McGowan, Erin M., Ehrlicher, Sarah E., Stierwalt, Harrison D., Newsom, Sean A., Robinson, Matthew M.

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Transient Activation of Skeletal Muscle Rac1 in Obesity-Related Insulin Resistance by STIERWALT, HARRISON D., BERGMAN, BRYAN, EHRLICHER, SARAH E., ROBINSON, MATTHEW M., NEWSOM, SEAN A.

“…Rac1 is required for normal insulin-stimulated glucose transport in skeletal muscle and may be negatively regulated by lipids. We investigated if insulin…”
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