Search Results - "Steyer, Benjamin"

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    Scarless Genome Editing of Human Pluripotent Stem Cells via Transient Puromycin Selection by Steyer, Benjamin, Bu, Qian, Cory, Evan, Jiang, Keer, Duong, Stella, Sinha, Divya, Steltzer, Stephanie, Gamm, David, Chang, Qiang, Saha, Krishanu

    Published in Stem cell reports (13-02-2018)
    “…Genome-edited human pluripotent stem cells (hPSCs) have broad applications in disease modeling, drug discovery, and regenerative medicine. We present and…”
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    Journal Article
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    High-Content Analysis of CRISPR-Cas9 Gene-Edited Human Embryonic Stem Cells by Carlson-Stevermer, Jared, Goedland, Madelyn, Steyer, Benjamin, Movaghar, Arezoo, Lou, Meng, Kohlenberg, Lucille, Prestil, Ryan, Saha, Krishanu

    Published in Stem cell reports (12-01-2016)
    “…CRISPR-Cas9 gene editing of human cells and tissues holds much promise to advance medicine and biology, but standard editing methods require weeks to months of…”
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    Journal Article
  4. 4

    Developing precision medicine using scarless genome editing of human pluripotent stem cells by Steyer, Benjamin, Cory, Evan, Saha, Krishanu

    Published in Drug discovery today. Technologies (01-08-2018)
    “…Many avenues exist for human pluripotent stem cells (hPSCs) to impact medical care, but they may have their greatest impact on the development of precision…”
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    Journal Article
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    High content analysis platform for optimization of lipid mediated CRISPR-Cas9 delivery strategies in human cells by Steyer, Benjamin, Carlson-Stevermer, Jared, Angenent-Mari, Nicolas, Khalil, Andrew, Harkness, Ty, Saha, Krishanu

    Published in Acta biomaterialia (01-04-2016)
    “…[Display omitted] Non-viral gene-editing of human cells using the CRISPR-Cas9 system requires optimized delivery of multiple components. Both the Cas9…”
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    Journal Article
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    Drug-loaded nanoparticles induce gene expression in human pluripotent stem cell derivatives by Gajbhiye, Virendra, Escalante, Leah, Chen, Guojun, Laperle, Alex, Zheng, Qifeng, Steyer, Benjamin, Gong, Shaoqin, Saha, Krishanu

    Published in Nanoscale (07-01-2014)
    “…Tissue engineering and advanced manufacturing of human stem cells requires a suite of tools to control gene expression spatiotemporally in culture. Inducible…”
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    Journal Article
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    Developing Precision Medicine for Best Vitelliform Macular Dystrophy with Genome Edited Human Pluripotent Stem Cells by Steyer, Benjamin Gabriel

    Published 01-01-2018
    “…Growing evidence supports the hypothesis that many individual diseases—such as cancer, Alzheimer’s, and diabetes—are actually collections of diverse syndromes…”
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    Dissertation
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    The Role of Syndecan‐1 in Arterial Mechanotransduction by Baker, Aaron B, Chitalia, Vipul, Steyer, Benjamin G, Hirji, Sameer, Edelman, Elazer R

    Published in The FASEB journal (01-04-2010)
    “…Hemodynamic forces induced by blood flow are potent regulators of vascular homeostasis and arterial structure. While previous work has focused on the role of…”
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    Journal Article