Search Results - "Stewart Dawe, Gavin"

A role for sorting nexin 27 in AMPA receptor trafficking by Loo, Li Shen, Tang, Ning, Al-Haddawi, Muthafar, Stewart Dawe, Gavin, Hong, Wanjin

“…Sorting nexin 27 (SNX27), a PDZ domain-containing endosomal protein, was recently shown to modulate glutamate receptor recycling in Down’s syndrome. However,…”
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NogoR1 and PirB Signaling Stimulates Neural Stem Cell Survival and Proliferation by Ramasamy, Srinivas, Yu, Fenggang, Hong Yu, Yuan, Srivats, Hariharan, Stewart Dawe, Gavin, Ahmed, Sohail

“…Neural stem cells (NSCs) and neural progenitors (NPs) in the mammalian neocortex give rise to the main cell types of the nervous system. The biological…”
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A Flexi‐PEGDA Upconversion Implant for Wireless Brain Photodynamic Therapy by Teh, Daniel Boon Loong, Bansal, Akshaya, Chai, Chou, Toh, Tan Boon, Tucker, Robert Alan Jappy, Gammad, Gil Gerald Lasam, Yeo, Yanzhuang, Lei, Zhendong, Zheng, Xiang, Yang, Fengyuan, Ho, John S., Bolem, Nagarjun, Wu, Bing Cheng, Gnanasammandhan, Muthu Kumar, Hooi, Lissa, Dawe, Gavin Stewart, Libedinsky, Camilo, Ong, Wei‐Yi, Halliwell, Barry, Chow, Edward Kai‐Hua, Lim, Kah‐Leong, Zhang, Yong, Kennedy, Brian K.

“…Near‐infrared (NIR) activatable upconversion nanoparticles (UCNPs) enable wireless‐based phototherapies by converting deep‐tissue‐penetrating NIR to visible…”
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Intranasal administration of a stapled relaxin‐3 mimetic has anxiolytic‐ and antidepressant‐like activity in rats by Marwari, Subhi, Poulsen, Anders, Shih, Norrapat, Lakshminarayanan, Rajamani, Kini, R. Manjunatha, Johannes, Charles William, Dymock, Brian William, Dawe, Gavin Stewart

“…Background and Purpose Depression and anxiety are common causes of disability, and innovative tools and potential pharmacological targets are actively sought…”
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Hope for vascular cognitive impairment: Ac-YVAD-cmk as a novel treatment against white matter rarefaction by Lim, Yun-An, Tan, Li Si, Lee, Wei Thye, Sim, Wei Liang, Lv, Yang, Takakuni, Maki, Saito, Satoshi, Ihara, Masafumi, Arumugam, Thiruma Valavan, Chen, Christopher, Wong, Fred Wai-Shiu, Dawe, Gavin Stewart

“…Vascular cognitive impairment (VCI) is the second leading cause of dementia with limited treatment options, characterised by cerebral hypoperfusion-induced…”
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The Effects of CYP2C19 Genotype on Proxies of SSRI Antidepressant Response in the UK Biobank by Wong, Win Lee Edwin, Fabbri, Chiara, Laplace, Benjamin, Li, Danyang, van Westrhenen, Roos, Lewis, Cathryn M, Dawe, Gavin Stewart, Young, Allan H

“…Selective serotonin reuptake inhibitors (SSRIs) are the most commonly used psychopharmaceutical treatment for major depressive disorder (MDD), but individual…”
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Therapeutic effect of hydrogen sulfide-releasing L-Dopa derivative ACS84 on 6-OHDA-induced Parkinson's disease rat model by Xie, Li, Hu, Li-Fang, Teo, Xing Qi, Tiong, Chi Xin, Tazzari, Valerio, Sparatore, Anna, Del Soldato, Piero, Dawe, Gavin Stewart, Bian, Jin-Song

“…Parkinson's disease (PD), characterized by loss of dopaminergic neurons in the substantia nigra, is a neurodegenerative disorder of central nervous system. The…”
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Corticotropin-releasing factor infusion into nucleus incertus suppresses medial prefrontal cortical activity and hippocampo-medial prefrontal cortical long-term potentiation by Farooq, Usman, Rajkumar, Ramamoorthy, Sukumaran, Shalini, Wu, You, Tan, Wei Hao, Dawe, Gavin Stewart

“…The medial prefrontal cortex (mPFC) in the rat has been implicated in a variety of cognitive processes, including working memory and expression of fear memory…”
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Photodynamic Therapy: A Flexi‐PEGDA Upconversion Implant for Wireless Brain Photodynamic Therapy (Adv. Mater. 29/2020) by Teh, Daniel Boon Loong, Bansal, Akshaya, Chai, Chou, Toh, Tan Boon, Tucker, Robert Alan Jappy, Gammad, Gil Gerald Lasam, Yeo, Yanzhuang, Lei, Zhendong, Zheng, Xiang, Yang, Fengyuan, Ho, John S., Bolem, Nagarjun, Wu, Bing Cheng, Gnanasammandhan, Muthu Kumar, Hooi, Lissa, Dawe, Gavin Stewart, Libedinsky, Camilo, Ong, Wei‐Yi, Halliwell, Barry, Chow, Edward Kai‐Hua, Lim, Kah‐Leong, Zhang, Yong, Kennedy, Brian K.

“…An upconversion biocompatible implant is the first step of translating decades‐old near‐infrared nanotransducer research into wireless phototherapeutic devices…”
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The putative role of the relaxin-3/RXFP3 system in clinical depression and anxiety: A systematic literature review by Wong, Win Lee Edwin, Dawe, Gavin Stewart, Young, Allan H.

“…•Experimental evidence suggests that RXFP3 activation can reduce depressive- and anxiety-like behavior in rodents.•Acute RXFP3 activation increases food intake…”
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A 0.45 V 100-channel neural-recording IC with sub- μW/channel consumption in 0.18 μm CMOS by Han, Dong, Zheng, Yuanjin, Rajkumar, Ramamoorthy, Dawe, Gavin Stewart, Je, Minkyu

“…Neural prosthetics and personal healthcare have increasing need of high channel density low noise low power neural sensor interfaces. The input referred noise…”
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Stapled B chain analogues of relaxin‐3 retain biological activity by Dawe, Gavin Stewart, Jayakody, Tharindunee, Mawari, Subhi

“…Abstract only Relaxin‐3, the most recently discovered member of the relaxin/insulin‐like family of peptides, is involved in regulating stress and anxiety,…”
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Putative role of β‐arrestin 2 in regulating TNF signalling to NFκB pathway by Salai, Kaung Htet Tun, Lee, Jasinda, Dawe, Gavin Stewart, Lai, Mitchell Kim Peng

“…Background Neuroinflammation is one of the features observed in neurodegenerative diseases, and inflammatory cytokines and chemokines are two of the important…”
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Putative role of β‐arrestin 2 in regulating TNF signalling to NFκB pathway: Molecular and cell biology/neuroinflammation by Salai, Kaung Htet Tun, Lee, Jasinda, Dawe, Gavin Stewart, Lai, Mitchell Kim Peng

“…Abstract Background Neuroinflammation is one of the features observed in neurodegenerative diseases, and inflammatory cytokines and chemokines are two of the…”
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A 100-Channel 1-mW Implantable Neural Recording IC by Xiaodan Zou, Lei Liu, Jia Hao Cheong, Lei Yao, Peng Li, Ming-Yuan Cheng, Wang Ling Goh, Rajkumar, Ramamoorthy, Dawe, Gavin Stewart, Kuang-Wei Cheng, Minkyu Je

“…This paper presents a fully implantable 100-channel neural interface IC for neural activity monitoring. It contains 100-channel analog recording front-ends, 10…”
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Selective lesioning of nucleus incertus with corticotropin releasing factor-saporin conjugate by Lee, Liying Corinne, Rajkumar, Ramamoorthy, Dawe, Gavin Stewart

“…Abstract The nucleus incertus (NI), a brainstem nucleus found in the pontine periventricular grey, is the primary source of the neuropeptide relaxin-3 in the…”
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Specific inhibition of p25/Cdk5 activity by the Cdk5 inhibitory peptide reduces neurodegeneration in vivo by Sundaram, Jeyapriya Raja, Poore, Charlene Priscilla, Sulaimee, Noor Hazim Bin, Pareek, Tej, Asad, A B M A, Rajkumar, Ramamoorthy, Cheong, Wei Fun, Wenk, Markus R, Dawe, Gavin Stewart, Chuang, Kai-Hsiang, Pant, Harish C, Kesavapany, Sashi

“…The aberrant hyperactivation of Cyclin-dependent kinase 5 (Cdk5), by the production of its truncated activator p25, results in the formation of…”
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Hydrocarbon stapled B chain analogues of relaxin-3 retain biological activity by Jayakody, Tharindunee, Marwari, Subhi, Lakshminarayanan, Rajamani, Tan, Francis Chee Kuan, Johannes, Charles William, Dymock, Brian William, Poulsen, Anders, Herr, Deron Raymond, Dawe, Gavin Stewart

“…•Relaxin-3 binds and activates the receptor RXFP3 through its B chain, which is stabilised in an alpha-helical conformation by a disulphide bonded A chain.•The…”
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Corrigendum to “Selective lesioning of nucleus incertus with corticotropin releasing factor-saporin conjugate” [Brain Res. 1543 (2014) 179–190] by Corinne Lee, Liying, Rajkumar, Ramamoorthy, Stewart Dawe, Gavin

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Acute antipsychotic treatments induce distinct c-Fos expression patterns in appetite-related neuronal structures of the rat brain by Rajkumar, Ramamoorthy, See, Lionel Kee Yon, Dawe, Gavin Stewart

“…Abstract A number of atypical antipsychotic drugs are known to perturb appetite regulation causing greater hyperphagia in humans and rodents than earlier…”
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