Search Results - "Stewart, Sheryl A."
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Prostacylin receptor activation inhibits proliferation of aortic smooth muscle cells by regulating cAMP response element-binding protein- and pocket protein-dependent cyclin a gene expression
Published in Molecular pharmacology (01-08-2003)“…The prostanoid prostacyclin (PGI2) inhibits aortic smooth muscle cell proliferation by blocking cell cycle progression from G1-to S-phase. However, the…”
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Journal Article -
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Antimitogenesis Linked to Regulation of Skp2 Gene Expression
Published in The Journal of biological chemistry (09-07-2004)“…Prostacyclin has many effects in the vasculature; one of the less well understood is the ability to block cell cycle progression through G 1 phase. We…”
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Journal Article -
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Integrin-Mediated Adhesion Regulates ERK Nuclear Translocation and Phosphorylation of Elk-1
Published in The Journal of cell biology (16-04-2001)“…Integrin-mediated adhesion to the extracellular matrix permits efficient growth factor-mediated activation of extracellular signal-regulated kinases (ERKs)…”
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Antimitogenic effects of HDL and APOE mediated by Cox-2-dependent IP activation
Published in The Journal of clinical investigation (01-02-2004)“…HDL and its associated apo, APOE, inhibit S-phase entry of murine aortic smooth muscle cells. We report here that the antimitogenic effect of APOE maps to the…”
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Journal Article -
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Antimitogenic effects of prostacyclin on the G1 phase cyclin-dependent kinases
Published in Prostaglandins & other lipid mediators (01-12-2005)“…The prostanoid prostacyclin (PGI 2) inhibits proliferation of cultured vascular SMCs by inhibiting cell cycle progression from G1 to S phase. Progression…”
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Journal Article -
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Antimitogenic effects of HDL and APOE mediated by Cox-2–dependent IP activation
Published in The Journal of clinical investigation (15-02-2004)“…HDL and its associated apo, APOE, inhibit S-phase entry of murine aortic smooth muscle cells. We report here that the antimitogenic effect of APOE maps to the…”
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Journal Article -
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Antimitogenesis by prostacyclin linked to regulation of Skp2 gene expression
Published 01-01-2004“…Atherosclerosis and restenosis are proliferative vascular diseases involving, in part, deregulated vascular smooth muscle cell proliferation. The dysfunction…”
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Dissertation