Search Results - "Stewart, Brent W"

(R)‐Ketamine exerts antidepressant actions partly via conversion to (2R,6R)‐hydroxynorketamine, while causing adverse effects at sub‐anaesthetic doses by Zanos, Panos, Highland, Jaclyn N., Liu, Xin, Troppoli, Timothy A., Georgiou, Polymnia, Lovett, Jacqueline, Morris, Patrick J., Stewart, Brent W., Thomas, Craig J., Thompson, Scott M., Moaddel, Ruin, Gould, Todd D.

“…Background and Purpose (R)‐Ketamine (arketamine) may have utility as a rapidly acting antidepressant. While (R)‐ketamine has lower potency than (R,S)‐ketamine…”
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Experimenters’ sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor by Georgiou, Polymnia, Zanos, Panos, Mou, Ta-Chung M., An, Xiaoxian, Gerhard, Danielle M., Dryanovski, Dilyan I., Potter, Liam E., Highland, Jaclyn N., Jenne, Carleigh E., Stewart, Brent W., Pultorak, Katherine J., Yuan, Peixiong, Powels, Chris F., Lovett, Jacqueline, Pereira, Edna F. R., Clark, Sarah M., Tonelli, Leonardo H., Moaddel, Ruin, Zarate, Carlos A., Duman, Ronald S., Thompson, Scott M., Gould, Todd D.

“…We show that the sex of human experimenters affects mouse behaviors and responses following administration of the rapid-acting antidepressant ketamine and its…”
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A role for the claustrum in cognitive control by Madden, Maxwell B, Stewart, Brent W, White, Michael G, Krimmel, Samuel R, Qadir, Houman, Barrett, Frederick S, Seminowicz, David A, Mathur, Brian N

“…Early hypotheses of claustrum function were fueled by neuroanatomical data and yielded suggestions that the claustrum is involved in processes ranging from…”
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The mouse claustrum synaptically connects cortical network motifs by Qadir, Houman, Stewart, Brent W., VanRyzin, Jonathan W., Wu, Qiong, Chen, Shuo, Seminowicz, David A., Mathur, Brian N.

“…Spatially distant areas of the cerebral cortex coordinate their activity into networks that are integral to cognitive processing. A common structural motif of…”
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Pathological claustrum activity drives aberrant cognitive network processing in human chronic pain by Stewart, Brent W, Keaser, Michael L, Lee, Hwiyoung, Margerison, Sarah M, Cormie, Matthew A, Moayedi, Massieh, Lindquist, Martin A, Chen, Shuo, Mathur, Brian N, Seminowicz, David A

“…Aberrant cognitive network activity and cognitive deficits are established features of chronic pain. However, the nature of cognitive network alterations…”
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(2R,6R)-hydroxynorketamine exerts mGlu₂ receptor-dependent antidepressant actions by Zanos, Panos, Highland, Jaclyn N., Stewart, Brent W., Georgiou, Polymnia, Jenne, Carleigh E., Lovett, Jacqueline, Morris, Patrick J., Thomas, Craig J., Moaddel, Ruin, Zarate, Carlos A., Gould, Todd D.

“…Currently approved antidepressant drugs often take months to take full effect, and ∼30% of depressed patients remain treatment resistant. In contrast,…”
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( 2R,6R )-hydroxynorketamine exerts mGlu 2 receptor-dependent antidepressant actions by Zanos, Panos, Highland, Jaclyn N, Stewart, Brent W, Georgiou, Polymnia, Jenne, Carleigh E, Lovett, Jacqueline, Morris, Patrick J, Thomas, Craig J, Moaddel, Ruin, Zarate, Jr, Carlos A, Gould, Todd D

“…Currently approved antidepressant drugs often take months to take full effect, and ∼30% of depressed patients remain treatment resistant. In contrast,…”
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