Search Results - "Steward Jr, Robert"

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    Bio-Inspired Microdevices that Mimic the Human Vasculature by Islam, Md Mydul, Beverung, Sean, Steward, Jr, Robert

    Published in Micromachines (Basel) (07-10-2017)
    “…Blood vessels may be found throughout the entire body and their importance to human life is undeniable. This is evident in the fact that a malfunctioning blood…”
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    Journal Article
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    Probing localized neural mechanotransduction through surface-modified elastomeric matrices and electrophysiology by LeDuc, Philip R, Chen, Chih-Cheng, Cheng, Chao-Min, Lin, Yi-Wen, Bellin, Robert M, Steward, Robert L, Cheng, Yuan-Ren

    Published in Nature protocols (01-04-2010)
    “…Mechanotransduction of sensory neurons is of great interest to the scientific community, especially in areas such as pain, neurobiology, cardiovascular…”
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    Journal Article
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    Illuminating human health through cell mechanics by Steward, Jr, Robert L, Rosner, Sonia R, Zhou, Enhua H, Fredberg, Jeffrey J

    Published in Swiss medical weekly (14-03-2013)
    “…Cells reside in mechanically rich and dynamic microenvironments, and the complex interplay between mechanics and biology is widely acknowledged. Recent…”
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    Journal Article
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    Extracellular matrix composition alters endothelial force transmission by Subramanian Balachandar, Vignesh Aravind, Steward, Jr, Robert L

    “…Extracellular matrix (ECM) composition is important in a host of pathophysiological processes such as angiogenesis, atherosclerosis, and diabetes, and during…”
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    Journal Article
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    Fluid shear, intercellular stress, and endothelial cell alignment by Steward, Jr, Robert, Tambe, Dhananjay, Hardin, C Corey, Krishnan, Ramaswamy, Fredberg, Jeffrey J

    “…Endothelial cell alignment along the direction of laminar fluid flow is widely understood to be a defining morphological feature of vascular homeostasis. While…”
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    Journal Article
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    Open-source, 3D-printed Peristaltic Pumps for Small Volume Point-of-Care Liquid Handling by Behrens, Michael R., Fuller, Haley C., Swist, Emily R., Wu, Jingwen, Islam, Md. Mydul, Long, Zhicheng, Ruder, Warren C., Steward, Robert

    Published in Scientific reports (31-01-2020)
    “…Microfluidic technologies are frequently employed as point-of-care diagnostic tools for improving time-to-diagnosis and improving patient outcomes in clinical…”
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    Journal Article
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    Lab-on-a-Chip for Cardiovascular Physiology and Pathology by Beverung, Sean, Wu, Jingwen, Steward, Jr, Robert

    Published in Micromachines (Basel) (28-09-2020)
    “…Lab-on-a-chip technologies have allowed researchers to acquire a flexible, yet relatively inexpensive testbed to study one of the leading causes of death…”
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    Journal Article
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    Variable fluid flow regimes alter human brain microvascular endothelial cell–cell junctions and cytoskeletal structure by Ranadewa, Dilshan, Wu, Jingwen, Subramanianbalachandar, Vignesh A., Steward, Robert L.

    Published in Cytoskeleton (Hoboken, N.J.) (01-06-2021)
    “…The human brain microvasculature is constantly exposed to variable fluid flow regimes and their influence on the endothelium depends in part on the synchronous…”
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    Journal Article
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    2D and 3D Mechanobiology in Human and Nonhuman Systems by Warren, Kristin M, Islam, Md. Mydul, LeDuc, Philip R, Steward, Robert

    Published in ACS applied materials & interfaces (31-08-2016)
    “…Mechanobiology involves the investigation of mechanical forces and their effect on the development, physiology, and pathology of biological systems. The human…”
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    Journal Article
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    Cellular force signal integration through vector logic gates by Steward, Robert L, Tan, Cheemeng, Cheng, Chao-Min, LeDuc, Philip R

    Published in Journal of biomechanics (26-02-2015)
    “…Abstract The multi-signal mechanical environment mammalian cells experience is often unaccounted for in current mechanical stimulation studies. To address this…”
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    Journal Article
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    Probing cell structure by controlling the mechanical environment with cell–substrate interactions by Cheng, Chao-Min, Steward, Robert L, LeDuc, Philip R

    Published in Journal of biomechanics (19-01-2009)
    “…Abstract Recent results demonstrate the exquisite sensitivity of cell morphology and structure to mechanical stimulation. Mechanical stimulation is often…”
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    Journal Article
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    Mechanical stretch and shear flow induced reorganization and recruitment of fibronectin in fibroblasts by Steward, Robert L., Cheng, Chao-Min, Ye, Jonathan D., Bellin, Robert M., LeDuc, Philip R.

    Published in Scientific reports (08-11-2011)
    “…It was our objective to study the role of mechanical stimulation on fibronectin (FN) reorganization and recruitment by exposing fibroblasts to shear fluid flow…”
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    Journal Article
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    Probing Cell Structure Responses Through a Shear and Stretching Mechanical Stimulation Technique by Steward, Robert L., Cheng, Chao-Min, Wang, Danny L., LeDuc, Philip R.

    Published in Cell biochemistry and biophysics (01-04-2010)
    “…Cells are complex, dynamic systems that respond to various in vivo stimuli including chemical, mechanical, and scaffolding alterations. The influence of…”
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    Journal Article
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    Probing Cellular Behavior Response Through Dual Mechanical Stimulation by Steward, Robert L

    Published 01-01-2011
    “…Cells have the astounding ability to sense and respond to numerous external mechanical stimuli. This stimuli which may be in the form of tension, compression,…”
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    Dissertation
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    Probing Cellular Behavior Response Through Dual Mechanical Stimulation by Steward, Robert L., Jr

    “…Cells have the astounding ability to sense and respond to numerous external mechanical stimuli. This stimuli which may be in the form of tension, compression,…”
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    Dissertation