Search Results - "Steward, Will P"

Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial by Valle, Juan W, Prof, Wasan, Harpreet, MD, Lopes, Andre, MSc, Backen, Alison C, PhD, Palmer, Daniel H, Prof, Morris, Karen, PhD, Duggan, Marian, MSc, Cunningham, David, Prof, Anthoney, D Alan, MD, Corrie, Pippa, MD, Madhusudan, Srinivasan, MD, Maraveyas, Anthony, Prof, Ross, Paul J, MD, Waters, Justin S, PhD, Steward, Will P, Prof, Rees, Charlotte, MD, Beare, Sandy, PhD, Dive, Caroline, Prof, Bridgewater, John A, MD

“…Summary Background Cisplatin and gemcitabine is the standard first-line chemotherapy regimen for patients with advanced biliary tract cancer; expression of…”
Get full text

Pancreatic stellate cells and pancreas cancer: Current perspectives and future strategies by Haqq, Jonathan, Howells, Lynne M, Garcea, Giuseppe, Metcalfe, Matthew S, Steward, Will P, Dennison, Ashley R

“…Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant disease with a very poor prognosis. To date patient outcomes have not…”
Get full text

Biomarkers for assessment of pharmacologic activity for a vascular endothelial growth factor (VEGF) receptor inhibitor, PTK787/ZK 222584 (PTK/ZK) : translation of biological activity in a mouse melanoma metastasis model to phase I studies in patients with advanced colorectal cancer with liver metastases by LEE, Lucy, SHARMA, Sunil, DREVS, Joachim, LEBWOHL, David, WOOD, Jeanette, MCSHEEHY, Paul M. J, MORGAN, Bruno, ALLEGRINI, Peter, SCHNELL, Christian, BRUEGGEN, Josef, COZENS, Robert, HORSFIELD, Mark, GUENTHER, Clemens, STEWARD, Will P

“…PTK/ZK is a novel, oral angiogenesis inhibitor that specifically targets all 3 vascular endothelial growth factor (VEGF) receptor tyrosine kinases and is…”
Get full text

Surgical bypass vs. endoscopic stenting for pancreatic ductal adenocarcinoma by Scott, Edwina N., Garcea, Giuseppe, Doucas, Helena, Steward, Will P., Dennison, Ashley R., Berry, David P.

“…The majority of patients with pancreatic cancer are non-resectable and jaundiced at presentation. Methods of palliation in such patients with locally advanced…”
Get full text

HYPOXIA AND ANGIOGENESIS IN PANCREATIC CANCER by Garcea, Giuseppe, Doucas, Helena, Steward, Will P., Dennison, Ashley R., Berry, David P.

“…Background:  Pancreatic cancer remains one of the most lethal of all solid tumours of the gastrointestinal tract. It is characterized by late diagnosis,…”
Get full text

Resveratrol —A prostate cancer chemopreventive agent? by Ratan, Hari L., Steward, Will P., Gescher, Andreas J., Mellon, J.Kilian

“…The incidence of prostate cancer in Western countries continues to rise. Whilst opinion remains divided on the best treatment for localized disease,…”
Get full text

Improving and predicting radiosensitivity in muscle invasive bladder cancer by Colquhoun, Alexandra J, Jones, George D D, Moneef, Manar Al, Bowman, Karen J, Kockelbergh, Roger C, Symonds, R Paul, Steward, Will P, Mellon, J Kilian

“…Muscle invasive bladder cancer is a common urological malignancy with a relatively poor prognosis and 5-year survival rates ranging from 20% to 90%. We review…”
Get more information

Chemoprevention of gastrointestinal malignancies by Garcea, Giuseppe, Dennison, Ashley R., Steward, Will P., Berry, David P.

“…Background:  There has been considerable interest in the use of chemical or dietary agents to suppress or inhibit the development of tumours in the early…”
Get full text

REVIEW ARTICLE: HYPOXIA AND ANGIOGENESIS IN PANCREATIC CANCER by Giuseppe Garcea, Helena Doucas, Will P Steward, Ashley R Dennison, David P Berry

“…Pancreatic cancer remains one of the most lethal of all solid tumours of the gastrointestinal tract. It is characterized by late diagnosis, aggressive local…”
Get full text

Vascular Endothelial Growth Factor (VEGF) Inhibition by Small Molecules by Ahmed, S.I., Thomas, A.L., Steward, W.P.

“…Angiogenesis is essential for primary tumours to grow and metastasise, and is driven by the production of positive angiogenic factors. The Vascular Endothelial…”
Get full text

Toxic megacolon: remember cytomegalovirus by Sharma, R A, Steward, W P, West, K P, Hemingway, D

“…A 63-year-old female retired clerical officer was admitted with a 1-week history of profuse diarrhoea. The patient had been diagnosed with non-Hodgkin's…”
Get full text

The importance of added albumin during continuous intravenous infusion of interleukin-2 with alpha-interferon by Cassidy, J, Poole, C, Sharkie, E, Steward, W P, Kaye, S B

“…We treated 14 patients (4 malignant melanoma/10 renal carcinoma) with a combination of continuous infusion interleukin-2 (IL-2) and subcutaneous…”
Get more information

Three months' treatment with cyclophosphamide, VP-16-213 followed by methotrexate and thoracic radiotherapy for small cell lung cancer by Thatcher, N, James, R D, Steward, W P, Barber, P V, Feinmann, D, Lawson, B A, Carroll, K B

“…One hundred eleven patients with inoperable but limited-stage small cell lung cancer were treated with three courses of cyclophosphamide (1.5, 2.5, and 3.5…”
Get more information

A phase II study of cyclophosphamide as a 24-hr infusion in advanced non-small cell lung cancer by Smith, D B, Thatcher, N, Steward, W P, Brear, G, Carroll, K B

“…Twenty patients with progressive non-small cell lung cancer who had received no prior chemotherapy were treated with 24-hr infusions of cyclophosphamide at a…”
Get more information