Search Results - "Stevic, Ivan"

Effect of endothelium on the anticoagulant activity of a covalent antithrombin-heparin complex by Atkinson, Helen M., Stevic, Ivan, Berry, Leslie R., Chan, Anthony K. C.

“…We developed a covalent antithrombin-heparin complex (ATH) with superior In vivo anticoagulant efficacy compared to non-covalent antithrombin (AT) +…”
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Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice by Afraz, Sajjad, Stevic, Ivan, Matino, Davide, Wen, Jianping, Atkinson, Helen, Chan, Anthony K. C., Hortelano, Gonzalo

“…Hemophilia A is an X-linked recessive congenital bleeding disorder. Exogenous infusion of FVIII is the treatment of choice, and the development of…”
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Effects of prolonged tourniquet application on coagulation and fibrinolysis in rats by Chung, Jason, Mian, Owais, Stevic, Ivan, Afraz, Sajjad, Chan, Anthony, Chan, Howard, Evers, Bret M., Matino, Davide

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Every Tube Counts: reducing extra tubes drawn in the emergency department by Knauer, Michael, Stevic, Ivan, MacDonald, Christine, Bhayana, Vipin, Bolsover, Jade, Smith, Lori, Chin-Yee, Ian

“…A common practice exists in hospitals where extra tubes of blood are collected for possible add-on testing, this practice contributes to wastage of…”
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Heterogeneity in the reported values and methodologies for detecting plasma D-Dimer in rat models: A systematic review by Chung, Jason, Afraz, Sajjad, Germini, Federico, Stevic, Ivan, Matino, Davide, Chan, Anthony KC

“…Plasma D-Dimer (DD) is a degradation product of cross-linked fibrin and represents the activation of the fibrinolytic and coagulation system. Clinically, DD…”
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17β-estradiol attenuates exercise-induced neutrophil infiltration in men by MacNeil, Lauren G, Baker, Steven K, Stevic, Ivan, Tarnopolsky, Mark A

“…17β-estradiol (E2) attenuates exercise-induced muscle damage and inflammation in some models. Eighteen men completed 150 eccentric contractions after random…”
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Mechanism of inhibition of the prothrombinase complex by a covalent antithrombin-heparin complex by Stevic, Ivan, Berry, Leslie R, Chan, Anthony K C

“…Factor-Xa assembly into the prothrombinase complex decreases its availability for inhibition by antithrombin + unfractionated heparin (AT + UFH). We have…”
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Inhibition of the prothrombinase complex on red blood cells by heparin and covalent antithrombin-heparin complex by Stevic, Ivan, Chan, Howard H W, Berry, Leslie R, Chander, Ankush, Chan, Anthony K C

“…The role of red blood cells (RBCs) in coagulation is not well understood. Overt exposure of phosphatidylserine on surfaces of RBCs provide docking sites for…”
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Carotid artery dissections: Thrombosis of the false lumen by Stevic, Ivan, Chan, Howard H.W, Chan, Anthony K.C

“…Abstract Carotid artery dissections are the second leading cause of stroke in young adults. The hemostatic response to a dissection involves exposure of the…”
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Feasibility of opportunistic colorectal cancer screening of hospitalized patients in tertiary care and community hospitals by Stevic, Ivan, Singh, Harminder, Sokoro, AbdulRazaq

“…Abstract Background Population screening for colorectal cancer (CRC) remains low, requiring alternative approaches for increasing participation. Opportunistic…”
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Long term stability of lactate in uncentrifuged sodium fluoride/potassium oxalate blood collection tubes by Stevic, Ivan, Bolsover, Jade, Moore, Rick, Bhayana, Vipin

“…Delayed time from collection to centrifugation may cause erroneously high lactate levels in vitro (from continued blood cell metabolism under anaerobic…”
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Lack of interference of metronidazole with Roche cobas c502 and c702 chemistry tests by Jasani, Arish, Stevic, Ivan, Bhayana, Vipin, Rutledge, Angela C.

“…•Metronidazole’s absorbance peak near 340 nm may cause assay interference.•No significant interference was observed with Roche cobas c502/c702 chemistry…”
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Von Willebrand Factor Expression in Endothelium in a Co-Culturing System of Acute Lymphoblastic Leukemia by Tieu, Paul T.M., Stevic, Ivan, Matino, Davide, Chan, Anthony K.C.

“…Background: Acute lymphoblastic leukemia (ALL) is the most common cause of cancer and death from cancer among children, with an incidence of 1 in 1,750…”
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Effects of Prolonged Tourniquet Application on Coagulation and Fibrinolysis in Rats by Chung, Jason, Mian, Owais, Stevic, Ivan, Afraz, Sajjad, Chan, Anthony KC, Chan, Howard H.W., Evers, Bret M, Matino, Davide

“…Background Pneumatic tourniquets are routinely used in major orthopedic surgeries such as total knee arthroplasty (TKA) to occlude arterial flow, control…”
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Biochemistry tests in hospitalized COVID-19 patients: Experience from a Canadian tertiary care centre by Rutledge, Angela C., Choi, Yun-Hee, Karp, Igor, Bhayana, Vipin, Stevic, Ivan

“…•In COVID-19 patients, troponin T, C-reactive protein, and lactate were prognostic.•Initial troponin T and C-reactive protein were associated with longer…”
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Effect of unfractionated heparin and low molecular weight heparin on the clotting of platelet-reduced whole blood: an in-vitro study utilizing thromboelastography by Chung, Jason, Stevic, Ivan, Gantioqui, Jorell, Atkinson, Helen, Chan, Anthony K.C., Chan, Howard H.W.

“…Treatment of venous thromboembolism with concomitant thrombocytopenia is challenging. The platelet threshold for safe administration of anticoagulants is under…”
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Rivaroxaban and dabigatran did not affect clotting profiles in plasma reconstituted with varying levels of autologous platelets to the same degree as heparin when evaluated using thromboelastography by Gantioqui, Jorell, Stevic, Ivan, Atkinson, Helen, Chan, Anthony K.C

“…OBJECTIVECurrent recommendations for treating patients with thromboembolism and concomitant thrombocytopenia are based on anecdotal data and expert opinion,…”
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Transient early increase in thyroglobulin levels post-radioiodine ablation in patients with differentiated thyroid cancer by Stevic, Ivan, Dembinski, Tom C., Pathak, K. Alok, Leslie, William D.

“…Treatment of differentiated thyroid cancer (DTC) includes surgical thyroidectomy and, in most cases, radioactive iodine (RAI) ablation. Measurement of serum…”
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Transient early increase in thyroglobulin levels post-radioiodine ablation in patients with differentiated thyroid cancer by Stevic, Ivan, Dembinski, Tom C., Leslie, William D.

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The Effects of Thrombocytopenia on Clotting Profile in Whole Blood As Determined By Thromboelastography When Anticoagulant Is Present at Therapeutic or Prophylactic Concentration by Chung, Jason, Stevic, Ivan, Gantioque, Jorell, Chan, Anthony K.C., Chan, Howard H.W.

“…Background: Anticoagulant therapy for the treatment of venous thromboembolism in patients with concomitant thrombocytopenia has been based on anecdotal…”
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