Search Results - "Steves, Claire J"

Vaccine side-effects and SARS-CoV-2 infection after vaccination in users of the COVID Symptom Study app in the UK: a prospective observational study by Menni, Cristina, Klaser, Kerstin, May, Anna, Polidori, Lorenzo, Capdevila, Joan, Louca, Panayiotis, Sudre, Carole H, Nguyen, Long H, Drew, David A, Merino, Jordi, Hu, Christina, Selvachandran, Somesh, Antonelli, Michela, Murray, Benjamin, Canas, Liane S, Molteni, Erika, Graham, Mark S, Modat, Marc, Joshi, Amit D, Mangino, Massimo, Hammers, Alexander, Goodman, Anna L, Chan, Andrew T, Wolf, Jonathan, Steves, Claire J, Valdes, Ana M, Ourselin, Sebastien, Spector, Tim D

“…The Pfizer-BioNTech (BNT162b2) and the Oxford-AstraZeneca (ChAdOx1 nCoV-19) COVID-19 vaccines have shown excellent safety and efficacy in phase 3 trials. We…”
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The fecal metabolome as a functional readout of the gut microbiome by Zierer, Jonas, Jackson, Matthew A., Kastenmüller, Gabi, Mangino, Massimo, Long, Tao, Telenti, Amalio, Mohney, Robert P., Small, Kerrin S., Bell, Jordana T., Steves, Claire J., Valdes, Ana M., Spector, Tim D., Menni, Cristina

“…The human gut microbiome plays a key role in human health 1 , but 16S characterization lacks quantitative functional annotation 2 . The fecal metabolome…”
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Real-time tracking of self-reported symptoms to predict potential COVID-19 by Menni, Cristina, Valdes, Ana M., Freidin, Maxim B., Sudre, Carole H., Nguyen, Long H., Drew, David A., Ganesh, Sajaysurya, Varsavsky, Thomas, Cardoso, M. Jorge, El-Sayed Moustafa, Julia S., Visconti, Alessia, Hysi, Pirro, Bowyer, Ruth C. E., Mangino, Massimo, Falchi, Mario, Wolf, Jonathan, Ourselin, Sebastien, Chan, Andrew T., Steves, Claire J., Spector, Tim D.

“…A total of 2,618,862 participants reported their potential symptoms of COVID-19 on a smartphone-based app. Among the 18,401 who had undergone a SARS-CoV-2…”
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Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study by Antonelli, Michela, Penfold, Rose S, Merino, Jordi, Sudre, Carole H, Molteni, Erika, Berry, Sarah, Canas, Liane S, Graham, Mark S, Klaser, Kerstin, Modat, Marc, Murray, Benjamin, Kerfoot, Eric, Chen, Liyuan, Deng, Jie, Österdahl, Marc F, Cheetham, Nathan J, Drew, David A, Nguyen, Long H, Pujol, Joan Capdevila, Hu, Christina, Selvachandran, Somesh, Polidori, Lorenzo, May, Anna, Wolf, Jonathan, Chan, Andrew T, Hammers, Alexander, Duncan, Emma L, Spector, Tim D, Ourselin, Sebastien, Steves, Claire J

“…COVID-19 vaccines show excellent efficacy in clinical trials and effectiveness in real-world data, but some people still become infected with SARS-CoV-2 after…”
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Proton pump inhibitors alter the composition of the gut microbiota by Jackson, Matthew A, Goodrich, Julia K, Maxan, Maria-Emanuela, Freedberg, Daniel E, Abrams, Julian A, Poole, Angela C, Sutter, Jessica L, Welter, Daphne, Ley, Ruth E, Bell, Jordana T, Spector, Tim D, Steves, Claire J

“…Proton pump inhibitors (PPIs) are drugs used to suppress gastric acid production and treat GI disorders such as peptic ulcers and gastro-oesophageal reflux…”
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Gut microbiota associations with common diseases and prescription medications in a population-based cohort by Jackson, Matthew A., Verdi, Serena, Maxan, Maria-Emanuela, Shin, Cheol Min, Zierer, Jonas, Bowyer, Ruth C. E., Martin, Tiphaine, Williams, Frances M. K., Menni, Cristina, Bell, Jordana T., Spector, Tim D., Steves, Claire J.

“…The human gut microbiome has been associated with many health factors but variability between studies limits exploration of effects between them. Gut…”
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Estrogen and COVID-19 symptoms: Associations in women from the COVID Symptom Study by Costeira, Ricardo, Lee, Karla A, Murray, Benjamin, Christiansen, Colette, Castillo-Fernandez, Juan, Ni Lochlainn, Mary, Capdevila Pujol, Joan, Macfarlane, Heather, Kenny, Louise C, Buchan, Iain, Wolf, Jonathan, Rymer, Janice, Ourselin, Sebastien, Steves, Claire J, Spector, Timothy D, Newson, Louise R, Bell, Jordana T

“…It has been widely observed that adult men of all ages are at higher risk of developing serious complications from COVID-19 when compared with women. This…”
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Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome by Pallister, Tess, Jackson, Matthew A., Martin, Tiphaine C., Zierer, Jonas, Jennings, Amy, Mohney, Robert P., MacGregor, Alexander, Steves, Claire J., Cassidy, Aedin, Spector, Tim D., Menni, Cristina

“…Reduced gut microbiome diversity is associated with multiple disorders including metabolic syndrome (MetS) features, though metabolomic markers have not been…”
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Circulating Levels of the Short-Chain Fatty Acid Acetate Mediate the Effect of the Gut Microbiome on Visceral Fat by Nogal, Ana, Louca, Panayiotis, Zhang, Xinyuan, Wells, Philippa M, Steves, Claire J, Spector, Tim D, Falchi, Mario, Valdes, Ana M, Menni, Cristina

“…Acetate is a short-chain fatty acid (SCFA) produced by gut bacteria, which has been implicated in cardio-metabolic health. Here we examine the relationships of…”
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Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom by Nguyen, Long H., Joshi, Amit D., Drew, David A., Merino, Jordi, Ma, Wenjie, Lo, Chun-Han, Kwon, Sohee, Wang, Kai, Graham, Mark S., Polidori, Lorenzo, Menni, Cristina, Sudre, Carole H., Anyane-Yeboa, Adjoa, Astley, Christina M., Warner, Erica T., Hu, Christina Y., Selvachandran, Somesh, Davies, Richard, Nash, Denis, Franks, Paul W., Wolf, Jonathan, Ourselin, Sebastien, Steves, Claire J., Spector, Tim D., Chan, Andrew T.

“…Worldwide, racial and ethnic minorities have been disproportionately impacted by COVID-19 with increased risk of infection, its related complications, and…”
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Association of social distancing and face mask use with risk of COVID-19 by Kwon, Sohee, Joshi, Amit D., Lo, Chun-Han, Drew, David A., Nguyen, Long H., Guo, Chuan-Guo, Ma, Wenjie, Mehta, Raaj S., Shebl, Fatma Mohamed, Warner, Erica T., Astley, Christina M., Merino, Jordi, Murray, Benjamin, Wolf, Jonathan, Ourselin, Sebastien, Steves, Claire J., Spector, Tim D., Hart, Jaime E., Song, Mingyang, VoPham, Trang, Chan, Andrew T.

“…Given the continued burden of COVID-19 worldwide, there is a high unmet need for data on the effect of social distancing and face mask use to mitigate the risk…”
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Illness duration and symptom profile in symptomatic UK school-aged children tested for SARS-CoV-2 by Molteni, Erika, Sudre, Carole H, Canas, Liane S, Bhopal, Sunil S, Hughes, Robert C, Antonelli, Michela, Murray, Benjamin, Kläser, Kerstin, Kerfoot, Eric, Chen, Liyuan, Deng, Jie, Hu, Christina, Selvachandran, Somesh, Read, Kenneth, Capdevila Pujol, Joan, Hammers, Alexander, Spector, Tim D, Ourselin, Sebastien, Steves, Claire J, Modat, Marc, Absoud, Michael, Duncan, Emma L

“…In children, SARS-CoV-2 infection is usually asymptomatic or causes a mild illness of short duration. Persistent illness has been reported; however, its…”
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Dietary Protein and Muscle in Aging People: The Potential Role of the Gut Microbiome by Ni Lochlainn, Mary, Bowyer, Ruth C E, Steves, Claire J

“…Muscle mass, strength, and physical function are known to decline with age. This is associated with the development of geriatric syndromes including sarcopenia…”
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Signatures of early frailty in the gut microbiota by Jackson, Matthew A, Jackson, Matt, Jeffery, Ian B, Beaumont, Michelle, Bell, Jordana T, Clark, Andrew G, Ley, Ruth E, O'Toole, Paul W, Spector, Tim D, Steves, Claire J

“…Frailty is arguably the biggest problem associated with population ageing, and associates with gut microbiome composition in elderly and care-dependent…”
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Increased habitual flavonoid intake predicts attenuation of cognitive ageing in twins by Jennings, Amy, Steves, Claire J, Macgregor, Alexander, Spector, Tim, Cassidy, Aedín

“…Although the pathophysiology of cognitive decline is multifactorial, and modifiable by lifestyle, the evidence for the role of diet on cognitive function is…”
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Nutrition and Frailty: Opportunities for Prevention and Treatment by Ni Lochlainn, Mary, Cox, Natalie J, Wilson, Thomas, Hayhoe, Richard P G, Ramsay, Sheena E, Granic, Antoneta, Isanejad, Masoud, Roberts, Helen C, Wilson, Daisy, Welch, Carly, Hurst, Christopher, Atkins, Janice L, Mendonça, Nuno, Horner, Katy, Tuttiett, Esme R, Morgan, Yvie, Heslop, Phil, Williams, Elizabeth A, Steves, Claire J, Greig, Carolyn, Draper, John, Corish, Clare A, Welch, Ailsa, Witham, Miles D, Sayer, Avan A, Robinson, Sian

“…Frailty is a syndrome of growing importance given the global ageing population. While frailty is a multifactorial process, poor nutritional status is…”
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An association between chronic widespread pain and the gut microbiome by Freidin, Maxim B, Stalteri, Maria A, Wells, Philippa M, Lachance, Genevieve, Baleanu, Andrei-Florin, Bowyer, Ruth C E, Kurilshikov, Alexander, Zhernakova, Alexandra, Steves, Claire J, Williams, Frances M K

“…Chronic widespread musculoskeletal pain (CWP) is a characteristic symptom of fibromyalgia, which has been shown to be associated with an altered gut…”
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Systematic identification of the role of gut microbiota in mental disorders: a TwinsUK cohort study by Delanote, Julie, Correa Rojo, Alejandro, Wells, Philippa M., Steves, Claire J., Ertaylan, Gökhan

“…Mental disorders are complex disorders influenced by multiple genetic, environmental, and biological factors. Specific microbiota imbalances seem to affect…”
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Use of dietary indices to control for diet in human gut microbiota studies by Bowyer, Ruth C E, Jackson, Matthew A, Pallister, Tess, Skinner, Jane, Spector, Tim D, Welch, Ailsa A, Steves, Claire J

“…Environmental factors have a large influence on the composition of the human gut microbiota. One of the most influential and well-studied is host diet. To…”
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Effect of gut microbiome modulation on muscle function and cognition: the PROMOTe randomised controlled trial by Ni Lochlainn, Mary, Bowyer, Ruth C. E., Moll, Janne Marie, García, María Paz, Wadge, Samuel, Baleanu, Andrei-Florin, Nessa, Ayrun, Sheedy, Alyce, Akdag, Gulsah, Hart, Deborah, Raffaele, Giulia, Seed, Paul T., Murphy, Caroline, Harridge, Stephen D. R., Welch, Ailsa A., Greig, Carolyn, Whelan, Kevin, Steves, Claire J.

“…Studies suggest that inducing gut microbiota changes may alter both muscle physiology and cognitive behaviour. Gut microbiota may play a role in both anabolic…”
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