Search Results - "Stevens‐Kroef, Marian J."
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1
Clonal evolution in myelodysplastic syndromes
Published in Nature communications (21-04-2017)“…Cancer development is a dynamic process during which the successive accumulation of mutations results in cells with increasingly malignant characteristics…”
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HER2, chromosome 17 polysomy and DNA ploidy status in breast cancer; a translational study
Published in Scientific reports (12-08-2019)“…Breast cancer treatment depends on human epidermal growth factor receptor-2 (HER2) status, which is often determined using dual probe fluorescence in situ…”
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Genomic array as compared to karyotyping in myelodysplastic syndromes in a prospective clinical trial
Published in Genes chromosomes & cancer (01-07-2017)“…Karyotyping is considered as the gold standard in the genetic subclassification of myelodysplastic syndrome (MDS). Oligo/SNP‐based genomic array profiling is a…”
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Next-generation cytogenetics: Comprehensive assessment of 52 hematological malignancy genomes by optical genome mapping
Published in American journal of human genetics (05-08-2021)“…Somatic structural variants (SVs) are important drivers of cancer development and progression. In a diagnostic set-up, especially for hematological…”
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Survival Improvement over Time of 960 s-AML Patients Included in 13 EORTC-GIMEMA-HOVON Trials
Published in Cancers (11-11-2020)“…We report the outcomes of secondary acute myeloid leukemia (s-AML) patients included in one of 13 European Organisation for Research and Treatment of Cancer…”
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Implementation of erythroid lineage analysis by flow cytometry in diagnostic models for myelodysplastic syndromes
Published in Haematologica (Roma) (01-02-2017)“…Flow cytometric analysis is a recommended tool in the diagnosis of myelodysplastic syndromes. Current flow cytometric approaches evaluate the (im)mature…”
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Morphologically normal, CD30-negative B-lymphocytes with chromosome aberrations in classical Hodgkin's disease: the progenitor cell of the malignant clone?
Published in The Journal of pathology (01-12-1999)“…A recent study observed that numerical chromosome abnormalities in Hodgkin's disease (HD) are detected not only in morphologically abnormal…”
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Identification of prognostic relevant chromosomal abnormalities in chronic lymphocytic leukemia using microarray-based genomic profiling
Published in Molecular cytogenetics (09-01-2014)“…Characteristic genomic abnormalities in patients with B cell chronic lymphocytic leukemia (CLL) have been shown to provide important prognostic information…”
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Microarray-based genomic profiling and in situ hybridization on fibrotic bone marrow biopsies for the identification of numerical chromosomal abnormalities in myelodysplastic syndrome
Published in Molecular cytogenetics (28-05-2015)“…Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematological malignancies. In MDS patients with a fibrotic bone marrow the aspiration of…”
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Melphalan, prednisone, and lenalidomide versus melphalan, prednisone, and thalidomide in untreated multiple myeloma
Published in Blood (03-03-2016)“…The combination of melphalan, prednisone, and thalidomide (MPT) is considered standard therapy for newly diagnosed patients with multiple myeloma who are…”
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