Search Results - "Stevens, Y W"

Structure, dissociation, and proteolysis of mammalian steroid receptors. Multiplicity of glucocorticoid receptor forms and proteolytic enzymes in rat liver and kidney cytosols by Sherman, M R, Moran, M C, Tuazon, F B, Stevens, Y W

“…The forms of steroid receptors detected in mammalian tissue cytosols vary from a globular fragment, the mero-receptor, with a molecular weight (Mr) of…”
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Agency for Toxic Substances and Disease Registry's 1997 priority list of hazardous substances. Latent effects—carcinogenesis, neurotoxicology, and developmental deficits in humans and animals by Ostrowski, Stephanie R., Wilbur, Sharon, Chou, C.-H. Selene J., Pohl, Hana R., Stevens, Yee-Wan, Allred, Phillip M., Roney, Nickolette, Fay, Mike, Tylenda, Carolyn A.

“…In support of Superfund re-authorization legislation, the Division of Toxicology of the Agency for Toxic Substances and Disease Registry (ATSDR) prepared a…”
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Phase I clinical and pharmacological study of merbarone by DIMAGGIO, J. J, WARRELL, R. P. JR, YOUNG, C. W, MUINDI, J, STEVENS, Y.-W, LEE, S. J, LOWENTHAL, D. A, HAINES, I, WALSH, T. D, BALTZER, L, YALDAEI, S

“…Merbarone, a nonsedating derivative of thiobarbituric acid, has demonstrated excellent activity against certain murine tumors, including L1210 and P388…”
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In vitro differential metabolism of merbarone by xanthine oxidase and microsomal flavoenzymes. The role of reactive oxygen species by Muindi, J F, Stevens, Y W, Warrell, Jr, R P, Young, C W

“…Merbarone (MB), a nonsedating derivative of thiobarbituric acid, was recently found to induce profound hypouricemia. When incubated with xanthine oxidase (XO)…”
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Health evaluation of 1,4-dioxane by DeRosa, C T, Wilbur, S, Holler, J, Richter, P, Stevens, Y W

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Role of risk assessment in public health practice by De Rosa, C T, Stevens, Y W, Johnson, B L

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Cancer policy framework for: public health assessment of carcinogens in the environment by DeRosa, C T, Stevens, Y W, Johnson, B L

“…Cancer remains at the forefront of public health concerns in the United States and throughout the world. Over the past 20 years a wide range of federal…”
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Induction of profound hypouricemia by a non-sedating thiobarbiturate by Warrell, Jr, R P, Muindi, J, Stevens, Y W, Isaacs, M, Young, C W

“…5-[N-phenylcarboxamido]-2-thiobarbituric acid (merbarone) is a non-sedating derivative of thiobarbituric acid originally developed for anticancer use. In the…”
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The Agency for Toxic Substances and Disease Registry's role in development and application of biomarkers in public health practice by Derosa, C T, Stevens, Y W, Wilson, J D, Ademoyero, A A, Buchanan, S D, Cibulas, Jr, W, Duerksen-Hughes, P J, Mumtaz, M M, Neft, R E, Pohl, H R

“…An overview of the Agency for Toxic Substances and Disease Registry's (ATSDR) biomarker program is presented in the context of the paradigm for biomarkers…”
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Multiple forms and fragments of cytosolic glucocorticoid receptors from human leukemic cells and normal lymphocytes by SHERMAN, M. R, YEE-WAN STEVENS, TUAZON, F. B

“…Therapy with glucocorticoids is generally more effective in acute lymphoblastic leukemia than in other types of human leukemia. Previous studies, however, have…”
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Nuclear glucocorticoid binding in chronic lymphatic leukemia lymphocytes by Stevens, J, Stevens, Y W, Sloan, E, Rosenthal, R, Rhodes, J

“…A reliable procedure is described for isolating 3H-triamcinolone acetonide (3H-TA) receptor complexes from purified chronic lymphatic leukemia (CLL) lymphocyte…”
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Early effects of glucocorticoid treatment on amino acid metabolism in lymphosarcoma P1798 by Stevens, J, Stevens, Y W, Hollander, V P

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Cortisol-induced lymphocytolysis of P1798 tumor cells in glucose-free, pyruvate-free medium by Stevens, J, Stevens, Y W

“…Exposure of corticoid-sensitive P1798 tumor lymphocytes to cortisol resulted in progressive cell dissolution either with or without exogenous glucose and…”
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Quantitation of merbarone in human plasma by high-performance liquid chromatography by Stevens, Y W, Walsh, T D, Fanucchi, M P

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Agency for Toxic Substances and Disease Registry's 1997 priority list of hazardous substances. Latent effects—carcinogenesis, neurotoxicology, and developmental deficits in humans and animals by Ostrowski, S.R., Wilbur, S., Chou, C-H.S.J., Pohl, H.R., Stevens, Y-W., Allred, P.M., Roney, N., Fay, M., Tylenda, C.A.

“…In support of Superfund re-authorization legislation, the Division of Toxicology of the Agency for Toxic Substances and Disease Registry (ATSDR) prepared a…”
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Role of nucleoside transport in glucocorticoid-induced regression of mouse lymphoma P1798 by Stevens, J, Stevens, Y W, Behrens, U, Hollander, V P

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Nuclear glucocorticoid binding in experimental and human leukemia by Stevens, J, Stevens, Y W, Rhodes, J, Sloan, E, Rosenthal, R L, Steiner, G

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Glucocorticoid inhibition of precursor incorporation into nuclear RNA of P1798 lymphosarcoma by Stevens, J, Mashburn, L T, Stevens, Y W, Hollander, V P

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4-Demethoxydaunorubicin (idarubicin) in combination with 1-β-D-arabinofuranosylcytosine in the treatment of relapsed or refractory acute leukemia by BERMAN, E, RAYMOND, V, YOUNG, C, AIMAN DAGHESTANI, ARLIN, Z. A, GEE, T. S, KEMPIN, S, HANCOCK, C, WILLIAMS, L, YEE-WAN STEVENS, CLARKSON, B. D

“…We conducted a Phase I-II trial of 4-demethoxydaunorubicin (idarubicin, IDR) in combination with 1-beta-D-arabinofuranosylcytosine (ara-C) in 51 patients with…”
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Phase I and clinical pharmacological study of 4-demethoxydaunorubicin (Idarubicin) in children with advanced cancer by TAN, C. T. C, HANCOCK, C, NIEDZWIECKI, D, STEVENS, Y.-W, STEINHERZ, P, BACHA, D. M, STEINHERZ, L, LUKS, E, WINICK, N, MEYERS, P, MONDORA, A, DANTIS, E

“…We conducted a phase I and pharmacokinetic study of i.v. idarubicin, a new anthracycline analogue, in 42 evaluable children 1-19 years old. Twenty-seven had…”
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