Search Results - "Stevens, RL"

Cooperative and Antagonistic Interplay between PU.1 and GATA-2 in the Specification of Myeloid Cell Fates by Walsh, Jonathan C., DeKoter, Rodney P., Lee, Hyun-Jun, Smith, Erica D., Lancki, David W., Gurish, Michael F., Friend, Daniel S., Stevens, Richard L., Anastasi, John, Singh, Harinder

“…PU.1 and GATA transcription factors appear to antagonize each other's function in the development of distinct lineages of the hematopoietic system. In…”
Get full text

DNA Amplification and Hybridization Assays in Integrated Plastic Monolithic Devices by Liu, Yingjie, Rauch, Cory B, Stevens, Randall L, Lenigk, Ralf, Yang, Jianing, Rhine, David B, Grodzinski, Piotr

“…PCR amplification, DNA hybridization, and a hybridization wash have been integrated in a disposable monolithic DNA device, containing all of the necessary…”
Get full text

Heparin is essential for the storage of specific granule proteases in mast cells by Humphries, Donald E, Stevens, Richard L, Wong, Guang W, Friend, Daniel S, Gurish, Michael F, Qiu, Wen-Tao, Huang, Chifu, Sharpe, Arlene H

“…All mammals produce heparin, a negatively charged glycosaminoglycan that is a major constituent of the secretory granules of mast cells which are found in the…”
Get full text

High sensitivity PCR assay in plastic micro reactors by Yang, Jianing, Liu, Yingjie, Rauch, Cory B, Stevens, Rauch L, Liu, Randall H, Lenigk, Robin, Grodzinski, Piotr

“…Small volume operation and rapid thermal cycling have been subjects of numerous reports in micro reactor chip development. Sensitivity aspects of the micro PCR…”
Get more information

Human Ecalectin, a Variant of Human Galectin-9, Is a Novel Eosinophil Chemoattractant Produced by T Lymphocytes by Matsumoto, R, Matsumoto, H, Seki, M, Hata, M, Asano, Y, Kanegasaki, S, Stevens, R L, Hirashima, M

“…A 1.6-kilobase pair cDNA was isolated from a human T-cell-derived expression library that encodes a novel eosinophil chemoattractant (designated ecalectin)…”
Get full text

Mast Cell Restricted, Tetramer-forming Tryptases Hinder Thrombin-Induced Coagulation of Plasma by Proteolytically Destroying Fibrinogen by Prieto-García, A, Castells, M, Wang, S, Stevens, R.L

“…Sodium citrate-treated human plasma also was incubated at 37oC for 60 min in the absence or presence of hTryptase-beta (6.6 μg) or heparin (100 μg), and the…”
Get full text

Human and mouse mast cells use the tetraspanin CD9 as an alternate interleukin-16 receptor by Qi, Jian C., Wang, Jing, Mandadi, Sravan, Tanaka, Kumiko, Roufogalis, Basil D., Madigan, Michele C., Lai, Kenneth, Yan, Feng, Chong, Beng H., Stevens, Richard L., Krilis, Steven A.

“…Interleukin-16 (IL-16) induces the chemotaxis and activation of mast cells (MCs) and other cell types. While it has been concluded that CD4 is the primary…”
Get full text

Evaluation of the Substrate Specificity of Human Mast Cell Tryptase βI and Demonstration of Its Importance in Bacterial Infections of the Lung by Huang, Chifu, De Sanctis, George T., O'Brien, Peter J., Mizgerd, Joseph P., Friend, Daniel S., Drazen, Jeffrey M., Brass, Lawrence F., Stevens, Richard L.

“…Human pulmonary mast cells (MCs) express tryptases α and βI, and both granule serine proteases are exocytosed during inflammatory events. Recombinant forms of…”
Get full text

Mast Cell Protease 5 Mediates Ischemia-Reperfusion Injury of Mouse Skeletal Muscle by Abonia, J. Pablo, Friend, Daniel S, Austen, William G., Jr, Moore, Francis D., Jr, Carroll, Michael C, Chan, Rodney, Afnan, Jalil, Humbles, Alison, Gerard, Craig, Knight, Pamela, Kanaoka, Yoshihide, Yasuda, Shinsuke, Morokawa, Nasa, Austen, K. Frank, Stevens, Richard L, Gurish, Michael F

“…Ischemia with subsequent reperfusion (IR) injury is a significant clinical problem that occurs after physical and surgical trauma, myocardial infarction, and…”
Get full text

Mouse Chromosome 17A3.3 Contains 13 Genes That Encode Functional Tryptic-like Serine Proteases with Distinct Tissue and Cell Expression Patterns by Wong, Guang W., Yasuda, Shinsuke, Morokawa, Nasa, Li, Lixin, Stevens, Richard L.

“…Probing of the mouse EST data base at GenBank™ with known tryptase cDNAs resulted in the identification of undiscovered serine protease transcripts whose genes…”
Get full text

RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function by Yang, Yi, Li, Lixin, Wong, Guang W, Krilis, Steven A, Madhusudhan, M S, Sali, Andrej, Stevens, Richard L

“…A cDNA was isolated from interleukin 3-developed, mouse bone marrow-derived mast cells (MCs) that contained an insert (designated mRasGRP4) that had not been…”
Get full text

Emergent epileptiform activity in neural networks with weak excitatory synapses by van Drongelen, W., Lee, H.C., Hereld, M., Zheyan Chen, Elsen, F.P., Stevens, R.L.

“…Brain electrical activity recorded during an epileptic seizure is frequently associated with rhythmic discharges in cortical networks. Current opinion in…”
Get full text

Biochemical and Functional Characterization of Human Transmembrane Tryptase (TMT)/Tryptase γ by Wong, Guang W., Foster, Paul S., Yasuda, Shinsuke, Qi, Jian C., Mahalingam, Surendran, Mellor, Elizabeth A., Katsoulotos, Gregory, Li, Lixin, Boyce, Joshua A., Krilis, Steven A., Stevens, Richard L.

Get full text

Mast Cells That Reside at Different Locations in the Jejunum of Mice Infected with Trichinella spiralis Exhibit Sequential Changes in Their Granule Ultrastructure and Chymase Phenotype by Friend, Daniel S., Ghildyal, Namit, Austen, K. Frank, Gurish, Michael F., Matsumoto, Ryoji, Stevens, Richard L.

“…Whether or not a nontransformed, mature mouse mast cell (MC) or its committed progenitor can change its granule protease phenotype during inflammatory…”
Get full text

Induction of a Selective and Persistent Extravasation of Neutrophils into the Peritoneal Cavity by Tryptase Mouse Mast Cell Protease 6 by Huang, Chifu, Friend, Daniel S, Qiu, Wen-Tao, Wong, Guang W, Morales, Guillermo, Hunt, John, Stevens, Richard L

“…Recombinant mouse mast cell protease 6 (mMCP-6) was generated to study the role of this tryptase in inflammatory reactions. Seven to forty-eight hours after…”
Get full text

Quick clay—A case study of chemical perspective in Southwest Sweden by Andersson-Sköld, Yvonne, Torrance, J. Kenneth, Lind, Bo, Odén, Karin, Stevens, Rodney L., Rankka, Karin

“…Quick clay, a soil that changes from normal firm ground to a liquid mass when it is disturbed, has been involved in most of the large and serious clay slides…”
Get full text

Manganese authigenesis in the Landsort Deep, Baltic Sea by Lepland, Aivo, Stevens, Rodney L

“…Manganese mineralogy, because of its redox sensitivity, is a valuable parameter for interpreting water-column anoxia and sediment diagenesis. In the Baltic,…”
Get full text

Identification of a subgroup of glycosylphosphatidylinositol-anchored tryptases by Wong, G. William, Stevens, Richard L.

“…The tryptase locus on mouse chromosome 17A3.3 contains 13 genes that encode enzymatically active serine proteases with different tissue expression profiles and…”
Get full text

Provenance of silt and clay within sandy deposits of the Lithuanian coastal zone (Baltic Sea) by Kairytė, Milda, Stevens, Rodney L., Trimonis, Egidijus

“…Mineralogical analysis of the silt and clay fraction of sandy deposits of 37 surface samples and grain-size data are used to interpret sediment sources acting…”
Get full text

Human Tryptase ε (PRSS22), a New Member of the Chromosome 16p13.3 Family of Human Serine Proteases Expressed in Airway Epithelial Cells by Wong, Guang W., Yasuda, Shinsuke, Madhusudhan, Mallur S., Li, Lixin, Yang, Yi, Krilis, Steven A., Šali, Andrej, Stevens, Richard L.

“…Probing of the GenBankTMexpressed sequence tag (EST) data base with varied human tryptase cDNAs identified two truncated ESTs that subsequently were found to…”
Get full text