Search Results - "Steven K Libutti"

The North American Neuroendocrine Tumor Society Consensus Paper on the Surgical Management of Pancreatic Neuroendocrine Tumors by Howe, James R., Merchant, Nipun B., Conrad, Claudius, Keutgen, Xavier M., Hallet, Julie, Drebin, Jeffrey A., Minter, Rebecca M., Lairmore, Terry C., Tseng, Jennifer F., Zeh, Herbert J., Libutti, Steven K., Singh, Gagandeep, Lee, Jeffrey E., Hope, Thomas A., Kim, Michelle K., Menda, Yusuf, Halfdanarson, Thorvardur R., Chan, Jennifer A., Pommier, Rodney F.

“…This manuscript is the result of the North American Neuroendocrine Tumor Society consensus conference on the surgical management of pancreatic neuroendocrine…”
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Phase I and Pharmacokinetic Studies of CYT-6091, a Novel PEGylated Colloidal Gold-rhTNF Nanomedicine by LIBUTTI, Steven K, PACIOTTI, Giulio F, BYRNES, Adriana A, ALEXANDER, H. Richard, GANNON, William E, WALKER, Melissa, SEIDEL, Geoffrey D, YULDASHEVA, Nargiza, TAMARKIN, Lawrence

“…A novel nanomedicine, CYT-6091, constructed by simultaneously binding recombinant human tumor necrosis factor alpha (rhTNF) and thiolyated polyethylene glycol…”
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Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism by Scholl, Ute I, Goh, Gerald, Stölting, Gabriel, de Oliveira, Regina Campos, Choi, Murim, Overton, John D, Fonseca, Annabelle L, Korah, Reju, Starker, Lee F, Kunstman, John W, Prasad, Manju L, Hartung, Erum A, Mauras, Nelly, Benson, Matthew R, Brady, Tammy, Shapiro, Jay R, Loring, Erin, Nelson-Williams, Carol, Libutti, Steven K, Mane, Shrikant, Hellman, Per, Westin, Gunnar, Åkerström, Göran, Björklund, Peyman, Carling, Tobias, Fahlke, Christoph, Hidalgo, Patricia, Lifton, Richard P

“…Richard Lifton and colleagues identify somatic and germline mutations in the CACNA1D calcium channel gene in aldosterone-producing adenomas and primary…”
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Targeting the invincible barrier for drug delivery in solid cancers: interstitial fluid pressure by Libutti, Steven K, Tamarkin, Lawrence, Nilubol, Naris

“…Although a number of new systemic therapeutic options in patients with advanced solid cancers have emerged due to the improved knowledge of molecular…”
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Resection versus expectant management of small incidentally discovered nonfunctional pancreatic neuroendocrine tumors by Rosenberg, Alex M., BA, Friedmann, Patricia, MS, Del Rivero, Jaydira, MD, Libutti, Steven K., MD, Laird, Amanda M., MD

“…Background Sporadic, nonfunctional pancreatic neuroendocrine tumors (NF-PNETs) are diagnosed with increasing frequency. We compared the risk of tumor growth,…”
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Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas by Wang, Huan, Bender, Aaron, Wang, Peng, Karakose, Esra, Inabnet, William B., Libutti, Steven K., Arnold, Andrew, Lambertini, Luca, Stang, Micheal, Chen, Herbert, Kasai, Yumi, Mahajan, Milind, Kinoshita, Yayoi, Fernandez-Ranvier, Gustavo, Becker, Thomas C., Takane, Karen K., Walker, Laura A., Saul, Shira, Chen, Rong, Scott, Donald K., Ferrer, Jorge, Antipin, Yevgeniy, Donovan, Michael, Uzilov, Andrew V., Reva, Boris, Schadt, Eric E., Losic, Bojan, Argmann, Carmen, Stewart, Andrew F.

“…Although diabetes results in part from a deficiency of normal pancreatic beta cells, inducing human beta cells to regenerate is difficult. Reasoning that…”
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Pulsed-High Intensity Focused Ultrasound and Low Temperature–Sensitive Liposomes for Enhanced Targeted Drug Delivery and Antitumor Effect by DROMI, Sergio, FRENKEL, Victor, WOOD, Bradford J, LUK, Alfred, TRAUGHBER, Bryan, ANGSTADT, Mary, BUR, Monica, POFF, Jason, JIANWU XIE, LIBUTTI, Steven K, LI, King C. P

“…Purpose: To determine if pulsed-high intensity focused ultrasound (HIFU) could effectively serve as a source of hyperthermia with thermosensitive liposomes to…”
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Amino acids control blood glucose levels through mTOR signaling by Fan, Jialin, Yuan, Ziqiang, Burley, Stephen K., Libutti, Steven K., Zheng, X.F. Steven

“…Amino Acids are not only major nutrient sources, but also serve as chemical signals to control cellular growth. Rab1A recently emerged as a key component in…”
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Minimally Invasive Parathyroidectomy Versus Bilateral Neck Exploration for Primary Hyperparathyroidism by Laird, Amanda M., MD, Libutti, Steven K., MD

“…Primary hyperparathyroidism is a disease that is caused by excess parathyroid hormone (PTH) secretion from 1 or more of the parathyroid glands. Surgery is the…”
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Phase I Study of Heat-Deployed Liposomal Doxorubicin during Radiofrequency Ablation for Hepatic Malignancies by Wood, Bradford J., MD, Poon, Ronnie T., MD, Locklin, Julia K., RN, MS, MBA, Dreher, Matthew R., PhD, Ng, K.K., MD, Eugeni, Michelle, RN, Seidel, Geoffrey, RN, Dromi, Sergio, MD, Neeman, Ziv, MD, Kolf, Michael, PharmD, Black, Christopher D.V., PhD, Prabhakar, Raj, MBA, Libutti, Steven K., MD

“…Abstract Purpose A phase I dose escalation study was performed with systemically delivered lyso-thermosensitive liposomal doxorubicin (LTLD). The primary…”
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Treatment factors associated with long-term survival after cytoreductive surgery and regional chemotherapy for patients with malignant peritoneal mesothelioma by Alexander, H. Richard, MD, Bartlett, David L., MD, Pingpank, James F., MD, Libutti, Steven K., MD, Royal, Richard, MD, Hughes, Marybeth S., MD, Holtzman, Matthew, MD, Hanna, Nader, MD, Turner, Keli, MD, Beresneva, Tatiana, MD, Zhu, Yue, MD, MS

“…Objectives Malignant peritoneal mesothelioma (MPM) is a primary cancer that arises diffusely from the mesothelial cells lining the peritoneum. Morbidity and…”
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Of mice and men (in) and what I have learned from both by Libutti, Steven K., MD

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Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors by Dondossola, Eleonora, Dobroff, Andrey S., Marchiò, Serena, Cardó-Vila, Marina, Hosoya, Hitomi, Libutti, Steven K., Corti, Angelo, Sidman, Richard L., Arap, Wadih, Pasqualini, Renata

“…Circulating cancer cells can putatively colonize distant organs to form metastases or to reinfiltrate primary tumors themselves through a process termed “tumor…”
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Filamin A interacting protein 1‐like inhibits WNT signaling and MMP expression to suppress cancer cell invasion and metastasis by Kwon, Mijung, Lee, Soo Jin, Wang, Yarong, Rybak, Yevangelina, Luna, Alex, Reddy, Srilakshmi, Adem, Asha, Beaty, Brian T., Condeelis, John S., Libutti, Steven K.

“…Identifying key mediators of cancer invasion and metastasis is crucial to the development of new and more effective therapies. We previously identified FILamin…”
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Everolimus in Neuroendocrine Tumors of the Gastrointestinal Tract and Unknown Primary by Singh, Simron, Carnaghi, Carlo, Buzzoni, Roberto, Pommier, Rodney F, Raderer, Markus, Tomasek, Jiri, Lahner, Harald, Valle, Juan W, Voi, Maurizio, Bubuteishvili-Pacaud, Lida, Lincy, Jeremie, Wolin, Edward, Okita, Natsuko, Libutti, Steven K, Oh, Do-Youn, Kulke, Matthew, Strosberg, Jonathan, Yao, James C, Pavel, Marianne E, Fazio, Nicola

“…The RADIANT-4 randomized phase 3 study demonstrated significant prolongation of median progression-free survival (PFS) with everolimus compared to placebo…”
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A randomized controlled trial to evaluate outcomes with Aggrenox in patients with SARS-CoV-2 infection by Singla, Amit, Dadario, Nicholas B, Singla, Ashima, Greenberg, Patricia, Yan, Rachel, Nanda, Anil, Boison, Detlev, Malhotra, Rakesh, Patel, Sunil, Nipun, Suri, Maninderpal, Kaur, Castro, Dorothy, Bdiiwi, Sanaa, Boktor, Hala, Kyi, Htay Htay, Sutherland, Anne, Patrawalla, Amee, Ly, Kevin, Xie, Yingda, Sonig, Ashish, Khandelwal, Priyank, Liu, James, Koziol, Joseph, Finkle, Diana, Subanna, Sara, Libutti, Steven K

“…Coronavirus disease 2019 (COVID-19) is an immunoinflammatory and hypercoagulable state that contributes to respiratory distress, multi-organ dysfunction, and…”
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Localization of Insulinomas to Regions of the Pancreas by Intraarterial Calcium Stimulation: The NIH Experience by Guettier, Jean-Marc, Kam, Anthony, Chang, Richard, Skarulis, Monica C., Cochran, Craig, Alexander, H. Richard, Libutti, Steven K., Pingpank, James F., Gorden, Phillip

“…Context: Selective intraarterial calcium injection of the major pancreatic arteries with hepatic venous sampling [calcium arterial stimulation (CaStim)] has…”
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AAVP displaying octreotide for ligand-directed therapeutic transgene delivery in neuroendocrine tumors of the pancreas by Smith, Tracey L., Yuan, Ziqiang, Cardó-Vila, Marina, Claros, Carmen Sanchez, Adem, Asha, Cui, Min-Hui, Branch, Craig A., Gelovani, Juri G., Libutti, Steven K., Sidman, Richard L., Pasqualini, Renata, Arap, Wadih

“…Patients with inoperable or unresectable pancreatic neuroendocrine tumors (NETs) have limited treatment options. These rare human tumors often express…”
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Insulinoma by Mathur, Aarti, MD, Gorden, Philip, MD, Libutti, Steven K., MD, FACS

“…Insulinoma is a rare neuroendocrine tumor with an incidence of 4 per 1 million persons per year, which may occur as a unifocal sporadic event in patients…”
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Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling by Butner, Joseph D, Martin, Geoffrey V, Wang, Zhihui, Corradetti, Bruna, Ferrari, Mauro, Esnaola, Nestor, Chung, Caroline, Hong, David S, Welsh, James W, Hasegawa, Naomi, Mittendorf, Elizabeth A, Curley, Steven A, Chen, Shu-Hsia, Pan, Ping-Ying, Libutti, Steven K, Ganesan, Shridar, Sidman, Richard L, Pasqualini, Renata, Arap, Wadih, Koay, Eugene J, Cristini, Vittorio

“…Checkpoint inhibitor therapy of cancer has led to markedly improved survival of a subset of patients in multiple solid malignant tumor types, yet the factors…”
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