Search Results - "Stetsenko, D"

Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties by Miroshnichenko, S. K., Мирошниченко, Светлана, Patutina, O. A., Патутина, Ольга, Burakova, E. A., Буракова, Екатерина, Chelobanov, B. P., Челобанов, Борис, Fokina, A. A., Фокина, Алеся, Vlassov, V. V., Власов, Валентин, Altman, S., Zenkova, M. A., Зенкова, Марина, Stetsenko, D. A., Стеценко, Дмитрий

“…Here we describe a DNA analog in which the mesyl (methanesulfonyl) phosphoramidate group is substituted for the natural phosphodiester group at each…”
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Structure-activity relationship study of mesyl and busyl phosphoramidate antisense oligonucleotides for unaided and PSMA-mediated uptake into prostate cancer cells by Sergeeva, O, Akhmetova, E, Dukova, S, Beloglazkina, E, Uspenskaya, A, Machulkin, A, Stetsenko, D, Zatsepin, T

“…Phosphorothioate (PS) group is a key component of a majority of FDA approved oligonucleotide drugs that increase stability to nucleases whilst maintaining…”
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Phosphoryl guanidines: a new type of nucleic Acid analogues by Kupryushkin, M S, Pyshnyi, D V, Stetsenko, D A

“…A new type of nucleic acid analogues with a phosphoryl guanidine group is described. Oxidation of polymer-supported dinucleoside 2-cyanoethyl phosphite by…”
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New Zwitter-Ionic Oligonucleotides: Preparation and Complementary Binding by Patrushev, D. E., Burakova, E. A., Bizyaev, S. N., Fokina, A. A., Stetsenko, D. A.

“…New zwitter-ionic oligonucleotide derivatives containing 1,2,3,4-tetrahydroisoquinoline-7-sulfonyl phosphoramidate group are described. Automated synthesis of…”
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Activity of nsp14 Exonuclease from SARS-CoV-2 towards RNAs with Modified 3'-Termini by Yuyukina, S. K., Barmatov, A. E., Bizyaev, S. N., Stetsenko, D. A., Sergeeva, O. V., Zatsepin, T. S., Zharkov, D. O.

“…The COVID-19 pandemic has shown the urgent need for new treatments for coronavirus infections. Nucleoside analogs were successfully used to inhibit replication…”
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New Oligodeoxynucleotide Derivatives Containing N-(Sulfonyl)-Phosphoramide Groups by Burakova, E. A., Derzhalova, A. Sh, Chelobanov, B. P., Fokina, A. A., Stetsenko, D. A.

“…— New oligodeoxynucleotide derivatives containing N -( o -nitrobenzenesulfonyl)-phosphoramide (nosyl phosphoramide), N -(1-butanesulfonyl)-phosphoramide (busyl…”
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Methods for Molecular Evolution of Polymerases by Zhukov, S. A., Fokina, A. A., Stetsenko, D. A., Vasilyeva, S. V.

“…In 2018, three scientists shared the Nobel Prize in Chemistry: Frances H. Arnold, “for the directed evolution of enzymes”; George P. Smith and Sir Gregory P…”
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Erratum to: Methods for Molecular Evolution of Polymerases by Zhukov, S. A., Vasilyeva, S. V., Fokina, A. A., Stetsenko, D. A.

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New oligodeoxynucleotide derivatives containing N-(methanesulfonyl)-phosphoramidate (mesyl phosphoramidate) internucleotide group by Chelobanov, B. P., Burakova, E. A., Prokhorova, D. V., Fokina, A. A., Stetsenko, D. A.

“…Novel oligonucleotide derivatives containing N-(methanesulfonyl)-phosphoramidate (mesyl phosphoramidate) group have been described. Solid-phase synthesis of…”
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Template-Assisted Assembly of DNA Nanostructures from Branched Oligonucleotides by Fokina, A. A., Poletaeva, Yu. E., Burakova, E. A., Bakulina, A. Yu, Zatsepin, T. S., Ryabchikova, E. I., Stetsenko, D. A.

“…We have proposed previously a template-assisted method for 3D assembly of nucleic acid nanostructures. The method involved a branched oligonucleotide as a…”
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Antiviral Activity of Nanocomplexes of Antisense Oligonucleotides Targeting VP72 Protein in Vero Cells Infected by African Swine Fever Virus by Hakobyan, A. V., Burakova, E. A., Arabyan, E. A., Fokina, A. A., Kotsinyan, A. R., Vasilyeva, S. V., Zakaryan, O. S., Stetsenko, D. A.

“…Antiviral activity of antisense oligodeoxyribonucleotides with phosphorothioate or mesyl phosphoramidate internucleotidic groups targeting the main capsid…”
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Design and Visualization of DNA/RNA Nanostructures from Branched Oligonucleotides Using Blender Software by Bakulina, A. Yu, Rad’kova, Z. V., Burakova, E. A., Benassi, E., Zatsepin, T. S., Fokina, A. A., Stetsenko, D. A.

“…Recently, three-dimensional nucleic acid nanostructures have attracted great interest, which have been made available through the DNA origami technique. We…”
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Phosphate-modif ied CpG oligonucleotides induce in vitro maturation of human myeloid dendritic cells by Ostanin, A A, Leplina, O Y, Burakova, E A, Tyrinova, T V, Fokina, A A, Proskurina, A S, Bogachev, S S, Stetsenko, D A, Chernykh, E R

“…Myeloid dendritic cells (DCs) play an important role in the immune response; therefore, the search for compounds that can effectively activate DCs is a needful…”
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Nuclear delivery of oligonucleotides via nanocomposites based on TiO2 nanoparticles and polylysine by Chelobanov, B. P., Repkova, M. N., Baiborodin, S. I., Ryabchikova, E. I., Stetsenko, D. A.

“…The nuclear delivery of nucleic acid derivatives is an essential prerequisite for successful antisense therapy. Using laser confocal and electron microscopy,…”
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New oligodeoxyribonucleotide derivatives bearing internucleotide N-tosyl phosphoramidate groups: Synthesis and complementary binding to DNA and RNA by Prokhorova, D. V., Chelobanov, B. P., Burakova, E. A., Fokina, A. A., Stetsenko, D. A.

“…N -Sulfonyl phosphoramidate derivatives of oligodeoxyribonucleotides containing N -tosyl phosphoramidate groups are first reported. The synthesis is based on…”
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Impact of delivery method on antiviral activity of phosphodiester, phosphorothioate, and phosphoryl guanidine oligonucleotides in MDCK cells infected with H5N1 bird flu virus by Levina, A. S., Repkova, M. N., Chelobanov, B. P., Bessudnova, E. V., Mazurkova, N. A., Stetsenko, D. A., Zarytova, V. F.

“…We have previously described nanocomposites containing conjugates or complexes of native oligodeoxyribonucleotides with poly-L-lysine and TiO 2 nanoparticles…”
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Fluorescent labeling of Taqman oligonucleotide probes via Cu(I)-catalyzed alkyne-azide cycloaddition (CuAAC) click chemistry by Vasilyeva, S. V., Burakova, E. A., Zhdanova, L. G., Anisimenko, M. S., Stetsenko, D. A.

“…We describe an approach to the synthesis of TaqMan oligonucleotide probes that is based on Cu(I)-catalyzed alkyne-azide cycloaddition (CuAAC) click chemistry…”
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Identification of new differentiation inducing factors from Dictyostelium discoideum by Saito, Tamao, Taylor, Graham W., Yang, Ji-Chun, Neuhaus, David, Stetsenko, Dmitry, Kato, Atsushi, Kay, Robert R.

“…Developing Dictyostelium discoideum amoebae form a stalked fruiting body in which individual cells differentiate into either stalk cells or spores. The major…”
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A Convenient Solid-Phase Method for Synthesis of 3‘-Conjugates of Oligonucleotides by Stetsenko, Dmitry A, Gait, Michael J

“…We present a new procedure for the preparation of 3‘-conjugates of oligonucleotides through solid-phase synthesis. A suitable universal solid support was…”
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Phosphate-modified CpG oligonucleotides induce in vitro maturation of human myeloid dendritic cells by Ostanin, A. A., Leplina, O. Y., Burakova, E. A., Tyrinova, T. V., Fokina, A. A., Proskurina, A. S., Bogachev, S. S., Stetsenko, D. A., Chernykh, E. R.

“…Myeloid dendritic cells (DCs) play an important role in the immune response; therefore, the search for compounds that can effectively activate DCs is a needful…”
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