Search Results - "Steshina, Ekaterina Y"
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Transformation of the cerebellum into more ventral brainstem fates causes cerebellar agenesis in the absence of Ptf1a function
Published in Proceedings of the National Academy of Sciences - PNAS (29-04-2014)“…Model organism studies have demonstrated that cell fate specification decisions play an important role in normal brain development. Their role in human…”
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Early dorsomedial tissue interactions regulate gyrification of distal neocortex
Published in Nature communications (15-11-2019)“…The extent of neocortical gyrification is an important determinant of a species’ cognitive abilities, yet the mechanisms regulating cortical gyrification are…”
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Lmx1a is a master regulator of the cortical hem
Published in eLife (19-09-2023)“…Development of the nervous system depends on signaling centers - specialized cellular populations that produce secreted molecules to regulate neurogenesis in…”
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Phenotypic and genetic analysis of the cerebellar mutant tmgc26, a new ENU-induced ROR-alpha allele
Published in The European journal of neuroscience (01-09-2010)“…ROR‐alpha is an orphan nuclear receptor, inactivation of which cell‐autonomously blocks differentiation of cerebellar Purkinje cells with a secondary loss of…”
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Loss of Ptf1a Leads to a Widespread Cell-Fate Misspecification in the Brainstem, Affecting the Development of Somatosensory and Viscerosensory Nuclei
Published in The Journal of neuroscience (02-03-2016)“…The brainstem contains diverse neuronal populations that regulate a wide range of processes vital to the organism. Proper cell-fate specification decisions are…”
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Loss of imprinting at the Dlk1-Gtl2 locus caused by insertional mutagenesis in the Gtl2 5' region
Published in BMC genetics (03-10-2006)“…The Dlk1 and Gtl2 genes define a region of mouse chromosome 12 that is subject to genomic imprinting, the parental allele-specific expression of a gene…”
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A 178-kb BAC transgene imprints the mouse Gtl2 gene and localizes tissue-specific regulatory elements
Published in Genomics (San Diego, Calif.) (01-08-2004)“…The regulation of genomic imprinting, the allele-specific expression of an autosomal gene, is complex and poorly understood. Imprinted genes are organized in…”
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A mouse model for juvenile hydrocephalus
Published in Developmental biology (15-07-2009)Get full text
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