Search Results - "Sterovsky, Thomas"
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Generation of biologically active multi-sialylated recombinant human EPOFc in plants
Published in PloS one (25-01-2013)“…Hyperglycosylated proteins are more stable, show increased serum half-life and less sensitivity to proteolysis compared to non-sialylated forms. This applies…”
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Heterologous protein production using euchromatin-containing expression vectors in mammalian cells
Published in Nucleic acids research (18-09-2015)“…Upon stable cell line generation, chromosomal integration site of the vector DNA has a major impact on transgene expression. Here we apply an active gene…”
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Expression of functionally active sialylated human erythropoietin in plants
Published in Biotechnology journal (01-03-2013)“…Recombinant human erythropoietin (rhEPO), a glycohormone, is one of the leading biopharmaceutical products. The production of rhEPO is currently restricted to…”
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4
Powerful expression in Chinese Hamster Ovary cells using bacterial artificial chromosomes: parameters influencing productivity
Published in BMC proceedings (04-12-2013)“…Doc number: P25…”
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Protein-free transfection of CHO host cells with an IgG-fusion protein: Selection and characterization of stable high producers and comparison to conventionally transfected clones
Published in Biotechnology and bioengineering (15-04-2007)“…In order to improve the current techniques of cell cultivation in the absence of serum, we have developed a protein‐free transfection protocol for CHO cells,…”
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SNEV overexpression extends the life span of human endothelial cells
Published in Experimental cell research (01-04-2006)“…In a recent screening for genes downregulated in replicatively senescent human umbilical vein endothelial cells (HUVECs), we have isolated the novel protein…”
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