Search Results - "Sternlicht, Himan"

TCP1 complex is a molecular chaperone in tubulin biogenesis by Yaffe, Michael B, Farr, George W, Miklos, David, Horwich, Arthur L, Sternlicht, Mona L, Sternlicht, Himan

“…A role in folding of newly translated proteins in the cytosol of eukaryotes has been proposed for t-complex polypeptide-1 (TCP1), although its molecular…”
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The t-Complex Polypeptide 1 Complex is a Chaperonin for Tubulin and Actin in vivo by Sternlicht, Himan, Farr, George W., Sternlicht, Mona L., Driscoll, Jane K., Willison, Keith, Yaffe, Michael B.

“…A role in folding newly translated cytoskeletal proteins in the cytosol of eukaryotes has been proposed for t-complex polypeptide 1 (TCP1). In this study, we…”
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The Possible Role of Aromatic Residues of Clostridium acidi-urici Ferredoxin in Electron Transport by Packer, Elliot L., Sternlicht, Himan, Rabinowitz, Jesse C.

“…The13C-resonances of the 2′,6′-ring carbon atoms of both tyrosyl residues of Clostridium acidi-urici ferredoxin are shifted downfield in the oxidized and…”
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Interactions of Saccharides with Concanavalin A by Brewer, Curtis F., Marcus, Donald M., Grollman, Arthur P., Sternlicht, Himan

“…Previous studies (Kalb, A. J., and Levitzki, A. (1968) Biochem. J. 109, 669; Shoham, M., Kalb, A.J., and Pecht, I. (1973) Biochemistry 12, 1914) were…”
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Evidence That β-Tubulin Induces a Conformation Change in the Cytosolic Chaperonin Which Stabilizes Binding:  Implications for the Mechanism of Action by Dobrzynski, Jane K, Sternlicht, Mona L, Peng, Isaac, Farr, George W, Sternlicht, Himan

“…The class II chaperonin CCT facilitates protein folding by a process that is not well-understood. One striking feature of this chaperonin is its apparent…”
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Newly-Synthesized β-Tubulin Demonstrates Domain-Specific Interactions with the Cytosolic Chaperonin by Dobrzynski, Jane K, Sternlicht, Mona L, Farr, George W, Sternlicht, Himan

“…Tubulin folding requires two chaperone systems, i.e., the 900 kDa cytosolic chaperonin referred to as the TCP-1 complex or TRiC which facilitates folding of…”
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Site-directed mutagenesis of the GTP-binding domain of beta-tubulin by Farr, G W, Sternlicht, H

“…Tubulin binds guanine nucleotides with high affinity and specificity. GTP, an allosteric effector of microtubule assembly, requires Mg2+ for its interaction…”
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Carbon-13 nuclear magnetic resonance study of microtubule protein: evidence for a second colchicine site involved in the inhibition of microtubule assembly by Ringel, Israel, Sternlicht, Himan

“…A 13C nuclear magnetic resonance study of bovine microtubule protein was carried out at 43 kG in the presence and absence of colchicine 13C labeled at the…”
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A model of the nucleotide-binding site in tubulin by Sternlicht, Himan, Yaffe, Michael B., Farr, George W.

“…Tubulin uses GTP to regulate microtubule assembly and is thought to be a member of a class of GDP/GTP-binding proteins (G-proteins) as defined by Hughes…”
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α-Tubulin Influences Nucleotide Binding to β-Tubulin: An Assay Using Picomoles of Unpurified Protein by Farr, George W., Yaffe, Michael B., Sternlicht, Himan

“…Tubulin binds guanine nucleotides tightly within its β subunit. Whether the α subunit influences binding to this site has been unknown. This question was…”
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Expression of a human .alpha.-tubulin: properties of the isolated subunit by Yaffe, Michael B, Levison, Bruce S, Szasz, Joseph, Sternlicht, Himan

“…We examined the in vitro expression and biochemical properties of the isolated alpha subunit of tubulin both in rabbit reticulocyte lysates and in Escherichia…”
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Microtubule assembly is dependent on a cluster of basic residues in α-tubulin by SZASZ, J, YAFFE, M. B, ELZINGA, M, BLANK, G. S, STERNLICHT, H

“…Previous studies have shown that tubulin, a major protein component of the microtubule, is rendered assembly incompetent when a highly reactive lysine residue…”
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Ethoxyformylation of tubulin with [3H]diethyl pyrocarbonate: a reexamination of the mechanism of assembly inhibition by Levison, Bruce S, Wiemels, Joseph, Szasz, Joseph, Sternlicht, Himan

“…In this study we reexamined the basis for the profound inhibitory effects of low concentrations of diethyl pyrocarbonate (DEP) on tubulin's ability to assemble…”
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Structure-activity study of the inhibition of microtubule assembly in vitro by podophyllotoxin and its congeners by Loike, J D, Brewer, C F, Sternlicht, H, Gensler, W J, Horwitz, S B

“…This study investigates the inhibition of microtubule assembly in vitro by podophyllotoxin and its derivatives, which include in part the antitumor compounds…”
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Conformational analysis of podophyllotoxin and its congeners. Structure-activity relationship in microtubule assembly by Brewer, C. Fred, Loike, John D, Horwitz, Susan B, Sternlicht, Himan, Gensler, Walter J

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Metal ion binding to adenosine triphosphate. III. Kinetic analysis by Sternlicht, Himan, Jones, Daniel E, Kustin, Kenneth

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Scope and mechanism of carbohydrase action: stereospecific hydration of D-glucal catalyzed by α- and β-glucosidase by Hehre, Edward J, Genghof, Dorothy S, Sternlicht, Himan, Brewer, Curtis F

“…A unique demonstration is presented of the capacity of glycosidases to create anomeric configuration de novo. Purifed Candida tropicalis alpha-glucosidase and…”
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Carbon-13 nuclear magnetic resonance studies of heterogeneous systems. Amino acids bound to cationic exchange resins by Sternlicht, Himan, Kenyon, George L, Packer, E. L, Sinclair, James

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The possible structural and functional role of aromatic residues in bacterial ferredoxins by Packer, E L, Sternlicht, H, Rabinowitz, J C

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Microtubule assembly is dependent on a cluster of basic residues in .alpha.-tubulin by Szasz, Joseph, Yaffe, Michael B, Elzinga, Marshall, Blank, Gregory S, Sternlicht, Himan

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