Search Results - "Sterneck, Esta"

PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells by Sheshadri, Namratha, Poria, Dipak K., Sharan, Shikha, Hu, Ying, Yan, Chunhua, Koparde, Vishal N., Balamurugan, Kuppusamy, Sterneck, Esta

“…Cancer cells experience endoplasmic reticulum (ER) stress due to activated oncogenes and conditions of nutrient deprivation and hypoxia. The ensuing unfolded…”
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MAPK3/1 (ERK1/2) in Ovarian Granulosa Cells Are Essential for Female Fertility by Fan, Heng-Yu, Liu, Zhilin, Shimada, Masayuki, Sterneck, Esta, Johnson, Peter F, Hedrick, Stephen M, Richards, JoAnne S

“…A surge of luteinizing hormone (LH) from the pituitary gland triggers ovulation, oocyte maturation, and luteinization for successful reproduction in mammals…”
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Slug and E-Cadherin: Stealth Accomplices? by Sterneck, Esta, Poria, Dipak K., Balamurugan, Kuppusamy

“…During physiological epithelial-mesenchymal transition (EMT), which is important for embryogenesis and wound healing, epithelial cells activate a program to…”
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The Janus kinase 1 is critical for pancreatic cancer initiation and progression by Shrestha, Hridaya, Rädler, Patrick D., Dennaoui, Rayane, Wicker, Madison N., Rajbhandari, Nirakar, Sun, Yunguang, Peck, Amy R., Vistisen, Kerry, Triplett, Aleata A., Beydoun, Rafic, Sterneck, Esta, Saur, Dieter, Rui, Hallgeir, Wagner, Kay-Uwe

“…Interleukin-6 (IL-6)-class inflammatory cytokines signal through the Janus tyrosine kinase (JAK)/signal transducer and activator of transcription (STAT)…”
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Identification of a Src Tyrosine Kinase/SIAH2 E3 Ubiquitin Ligase Pathway That Regulates C/EBPδ Expression and Contributes to Transformation of Breast Tumor Cells by Sarkar, Tapasree Roy, Sharan, Shikha, Wang, Jun, Pawar, Snehalata A., Cantwell, Carrie A., Johnson, Peter F., Morrison, Deborah K., Wang, Ju-Ming, Sterneck, Esta

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C/EBPδ deficiency sensitizes mice to ionizing radiation-induced hematopoietic and intestinal injury by Pawar, Snehalata A, Shao, Lijian, Chang, Jianhui, Wang, Wenze, Pathak, Rupak, Zhu, Xiaoyan, Wang, Junru, Hendrickson, Howard, Boerma, Marjan, Sterneck, Esta, Zhou, Daohong, Hauer-Jensen, Martin

“…Knowledge of the mechanisms involved in the radiation response is critical for developing interventions to mitigate radiation-induced injury to normal tissues…”
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C/EBPδ targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression by Pawar, Snehalata A, Sarkar, Tapasree Roy, Balamurugan, Kuppusamy, Sharan, Shikha, Wang, Jun, Zhang, Youhong, Dowdy, Steven F, Huang, A. Mei, Sterneck, Esta

“…The transcription factor CCAAT/enhancer binding protein δ (C/EBPδ, CEBPD, NFIL-6β) has tumor suppressor function; however, the molecular mechanism(s) by which…”
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SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases by THANGARAJU, Muthusamy, GOPAL, Elangovan, MARTIN, Pamela M, ANANTH, Sudha, SMITH, Sylvia B, PRASAD, Puttur D, STERNECK, Esta, GANAPATHY, Vadivel

“…Tumor cells up-regulate glycolysis but convert pyruvate into lactate instead of oxidizing it. Here, we show that pyruvate, but not lactate, is an inhibitor of…”
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Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancer by Balamurugan, Kuppusamy, Poria, Dipak K, Sehareen, Saadiya W, Krishnamurthy, Savitri, Tang, Wei, McKennett, Lois, Padmanaban, Veena, Czarra, Kelli, Ewald, Andrew J, Ueno, Naoto T, Ambs, Stefan, Sharan, Shikha, Sterneck, Esta

“…Metastatic progression of epithelial cancers can be associated with epithelial-mesenchymal transition (EMT) including transcriptional inhibition of E-cadherin…”
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Transcriptional up-regulation of SOD1 by CEBPD: A potential target for cisplatin resistant human urothelial carcinoma cells by Hour, Tzyh-Chyuan, Lai, Yan-Liang, Kuan, Ching-I, Chou, Chen-Kung, Wang, Ju-Ming, Tu, Huang-Yao, Hu, Huei-Ting, Lin, Chang-Shen, Wu, Wen-Jeng, Pu, Yeong-Shiau, Sterneck, Esta, Huang, A-Mei

“…Bladder cancer is the fourth most common type of cancer in men (ninth in women) in the United States. Cisplatin is an effective agent against the most common…”
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CCAAT/enhancer binding protein delta (C/EBPδ, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage by Wang, Jun, Sarkar, Tapasree Roy, Zhou, Ming, Sharan, Shikha, Ritt, Daniel A, Veenstra, Timothy D, Morrison, Deborah K, Huang, A. Mei, Sterneck, Esta

“…Maintenance of genomic integrity is an essential cellular function. We previously reported that the transcription factor and tumor suppressor CCAAT/enhancer…”
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CCAAT/Enhancer Binding Protein-β is a Mediator of Keratinocyte Survival and Skin Tumorigenesis Involving Oncogenic Ras Signaling by Zhu, Songyun, Yoon, Kyungsil, Sterneck, Esta, Johnson, Peter F., Smart, Robert C.

“…The basic leucine zipper transcription factor CCAAT/enhancer binding protein-β (C/EBPβ) is expressed in many cell types, including keratinocytes. C/EBPβ…”
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An Essential Role for a MEK-C/EBP Pathway during Growth Factor-Regulated Cortical Neurogenesis by Ménard, Catherine, Hein, Paul, Paquin, Annie, Savelson, Aviva, Yang, Xiu Ming, Lederfein, Doron, Barnabé-Heider, Fanie, Mir, Alain A, Sterneck, Esta, Peterson, Alan C, Johnson, Peter F, Vinson, Charles, Miller, Freda D

“…Mammalian neurogenesis is determined by an interplay between intrinsic genetic mechanisms and extrinsic cues such as growth factors. Here we have defined a…”
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The many faces of C/EBPδ and their relevance for inflammation and cancer by Balamurugan, Kuppusamy, Sterneck, Esta

“…The CCAAT/enhancer binding protein delta (CEBPD, C/EBPδ) is a transcription factor that modulates many biological processes including cell differentiation,…”
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Loss of CCAAT/enhancer binding protein δ promotes chromosomal instability by HUANG, A-Mei, MONTAGNA, Cristina, SHARAN, Shikha, YAJUN NI, RIED, Thomas, STERNECK, Esta

“…The transcription factor CCAAT/enhancer binding protein delta (Cebpd, also known as C/EBPdelta, CRP3, CELF, NF-IL6beta) is implicated in diverse cellular…”
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Interleukin-6-Specific Activation of the C/EBPδ Gene in Hepatocytes Is Mediated by Stat3 and Sp1 by Cantwell, Carrie A., Sterneck, Esta, Johnson, Peter F.

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C/EBPβ Modulates the Early Events of Keratinocyte Differentiation Involving Growth Arrest and Keratin 1 and Keratin 10 Expression by Zhu, Songyun, Oh, Hye-Sun, Shim, Minsub, Sterneck, Esta, Johnson, Peter F., Smart, Robert C.

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The Cebpd (C/EBPdelta) gene is induced by luteinizing hormones in ovarian theca and interstitial cells but is not essential for mouse ovary function by Huang, A-Mei, Rudelius, Martina, Sharan, Shikha, McAllister, Jan M, Raffeld, Mark, Christenson, Lane K, Sterneck, Esta

“…The CCAAT/enhancer binding protein (CEBP) family of transcription factors includes five genes. In the ovary, both Cebpa and Cebpb are essential for granulosa…”
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Selectively Enhanced Contextual Fear Conditioning in Mice Lacking the Transcriptional Regulator CCAAT/Enhancer Binding Protein δ by Sterneck, Esta, Paylor, Richard, Jackson-Lewis, Vernice, Libbey, Megan, Przedborski, Serge, Tessarollo, Lino, Crawley, Jacqueline N., Johnson, Peter F.

“…CCAAT/enhancer binding protein δ (C/EBPδ ) is a transcriptional regulator implicated in the hepatic acute phase response and in adipogenic and myeloid cell…”
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The Lymphatic System in Mammary Gland Biology and Breast Cancer by Lyons, Traci R., Sterneck, Esta

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