Search Results - "Stern, P.H"

Dose-dependent differential effects of risedronate on gene expression in osteoblasts by Wang, J., Stern, P.H.

“…Bisphosphonates have multiple effects on bone. Their actions on osteoclasts lead to inhibition of bone resorption, at least partially through apoptosis…”
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Cyclosporine A and FK506 induce osteoclast apoptosis in mouse bone marrow cell cultures by Igarashi, K, Hirotani, H, Woo, J.-T, Stern, P.H

“…Studies were carried out to characterize the effects of cyclosporines and FK506 on the formation and survival of osteoclasts deriving from mouse bone marrow…”
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Antagonist minigenes identify genes regulated by parathyroid hormone through G protein-selective and G protein co-regulated mechanisms in osteoblastic cells by Wang, J., Gilchrist, A., Stern, P.H.

“…Parathyroid hormone (PTH) is the major hormone regulating bone remodeling. Binding of PTH to the PTH1 receptor (PTH1R), a heterotrimeric G protein coupled…”
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MicroCT quantification of in vitro bone resorption of neonatal murine calvaria exposed to IL-1 or PTH by Stock, S.R., Ignatiev, K.I., Foster, S.A., Forman, L.A., Stern, P.H.

“…This study investigated how effectively a laboratory microCT (X-ray micro-computed tomography) system can quantify bone resorption in an in vitro calvarial…”
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Endothelin-stimulated Ca2+signaling and endothelin receptor expression are decreased by parathyroid hormone treatment in UMR-106 osteoblastic osteosarcoma cells by Semler, D.E., Morris, D.L., Stern, P.H.

“…Modulation of endothelin (ET-1)-induced [Ca2+]itransients and receptor expression by parathyroid hormone (PTH) was studied in UMR-106 osteoblastic osteosarcoma…”
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RAT LIVER AND PLASMA LIPIDS AFTER CARBON TETRACHLORIDE ADMINISTRATION by STERN, P H, FURUKAWA, T, BRODY, T M

“…Oral administration of CCl4 to rats produced (a) decreased cholesterol, phospholipid, and triglyceride plasma concentrations and elevated triglyceride levels…”
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Parathyroid hormone stimulates translocation of protein kinase C isozymes in UMR-106 osteoblastic osteosarcoma cells by Dossing, D.A, Radeff, J.M, Sanders, J, Lee, S.-K, Hsieh, M.-R, Stern, P.H

“…Studies with antagonists have provided evidence that protein kinase C (PKC) is involved in several of the actions of parathyroid hormone (PTH) on bone. PTH…”
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In vitro mechanical and cellular responses of neonatal mouse bones to loading using a novel micromechanical-testing device by Kunnel, J G, Gilbert, J L, Stern, P H

“…Mechanical stimulation is critical for the maintenance of bone architecture and bone mass. These effects are dependent on the magnitude, duration, and rate of…”
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Cadmium Accelerates Bone Loss in Ovariectomized Mice and Fetal Rat Limb Bones in Culture by Bhattacharyya, M. H., Whelton, B. D., Stern, P. H., Peterson, D. P.

“…Loss of bone mineral after ovariectomy was studied in mice exposed to dietary cadmium at 0.25, 5, or 50 ppm. Results show that dietary cadmium at 50 ppm…”
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In vivo-Like Drug Responses of Human Tumors Growing in Three-Dimensional Gel-Supported Primary Culture by Vescio, Robert A., Redfern, Charles H., Nelson, Theodora J., Ugoretz, Scott, Stern, Peter H., Hoffman, Robert M.

“…An in vitro test of cell sensitivity to drugs that indicates in vivo response is an important need in cancer therapy and cancer drug development. Toward this…”
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Circadian rhythms in postmenopausal healthy and osteoporotic subjects by Lakatos, P., Balint, E., Luigitsch, I., Kiss, L., Földes, J., Steczek, K., Poteczin, E., Feher, T., Tarjan, G., Stern, P.H.

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Evaluation of the role of second messenger systems in tumor necrosis factor-stimulated resorption of fetal rat limb bones by Shankar, G, Stern, P H

“…Tumor necrosis factor (TNF) actions in target tissues are mediated by various signalling pathways. The effect of TNF to stimulate resorption in fetal rat limb…”
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Effects of gallium nitrate on calcium transients in UMR-106 rat osteoblastic osteosarcoma cells by Lakatos, P, Tatrai, A, Stern, P H

“…Gallium nitrate is an effective antihypercalcemic and antiresorptive agent. Although its effects on osteoclasts are well documented, the mechanism of action of…”
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Comparison of fetal rat limb bones and neonatal mouse calvaria: effects of parathyroid hormone and 1,25-dihydroxyvitamin D3 by Stern, P.H, Krieger, N.S

“…The relative responses of fetal rat limb bones and neonatal mouse calvaria to parathyroid hormone (PTH) and 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) were…”
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Biological activity of 1,25-dihydroxyvitamin D sub 2 and 24-epi-1,25-dihydroxyvitamin D sub 2 by DeLuca, H.F., Sicinski, R.R., Tanaka, Y., Stern, P.H., Smith, C.M.

“…The biological activity of 1,25-dihydroxyvitamin D{sub 2} (1,25(OH){sub 2}D{sub 2}) and 24-epi-1,25-dihydroxyvitamin D{sub 2} (24-epi-1,25(OH){sub 2}D{sub 2})…”
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Biological activity of 1,25-dihydroxyvitamin D2 and 24-epi-1,25-dihydroxyvitamin D2 by DeLuca, H.F, Sicinski, R.R, Tanaka, Y, Stern, P.H, Smith, C.M

“…The biological activity of 1,25-dihydroxyvitamin D2 [1,25(OH)2D2] and 24-epi-1,25-dihydroxyvitamin D2 [24-epi-1,25(OH)2D2] has been determined in vitamin…”
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Abnormal regulation of circulating 25-hydroxyvitamin D in the Williams syndrome by Taylor, A B, Stern, P H, Bell, N H

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The chemical synthesis of high specific-activity [35S]adenosylhomocysteine by Stern, P H, Hoffman, R M

“…The study of the family of transmethylases, critical to normal cellular function and often altered in cancer, can be facilitated by the availability of a high…”
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Bone resorbing activities of 24-hydroxy stereoisomers of 24-hydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 by Stern, P H, DeLuca, H F, Ikekawa, N

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24-Oxo and 26,23-lactone metabolites of 1,25-dihydroxyvitamin D3 have direct bone-resorbing activity by Stern, P H, Rappaport, M S, Mayer, E, Norman, A W

“…The biological activities of several 24-oxo and 26,23-lactone metabolites of vitamin D were determined in bone organ cultures. The 24-oxo metabolites were…”
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