Search Results - "Stern, Hannah R"

Mammalian DNA Polymerase Kappa Activity and Specificity by Stern, Hannah R, Sefcikova, Jana, Chaparro, Victoria E, Beuning, Penny J

“…DNA polymerase (pol) kappa is a Y-family translesion DNA polymerase conserved throughout all domains of life. Pol kappa is special6 ized for the ability to…”
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Engineering Polymerases for New Functions by Coulther, Timothy A, Stern, Hannah R, Beuning, Penny J

“…DNA polymerases are critical tools in biotechnology, enabling efficient and accurate amplification of DNA templates, yet many desired functions are not readily…”
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Characterization of Nine Cancer-Associated Variants in Human DNA Polymerase κ by Antczak, Nicole M, Walker, Alice R, Stern, Hannah R, Leddin, Emmett M, Palad, Carl, Coulther, Timothy A, Swett, Rebecca J, Cisneros, G. Andrés, Beuning, Penny J

“…Specialized DNA damage-bypass Y-family DNA polymerases contribute to cancer prevention by providing cellular tolerance to DNA damage that can lead to mutations…”
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Probing the role of distal residues in DinB and Pol Kappa in the extension step of DNA damage bypass by Stern, Hannah R., Mills, Caitlyn L., Ondrechen, Mary Jo, Beuning, Penny

“…DNA is constantly subjected to damage from endogenous and exogenous sources. Replicative DNA polymerases are typically unable to replicate damaged DNA, but…”
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Role of Pol κ and DinB distal residues on extension step of TLS by Stern, Hannah R, Mills, Caitlyn L, Ondrechen, Mary Jo, Beuning, Penny J

“…Abstract only DNA is subject to damage from endogenous and exogenous sources. Replicative DNA polymerases are typically unable to replicate damaged DNA, but…”
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